Digital Commons Network^™

An Interesting Case Of Modern Day Scurvy, Petar Jen, Jessica Cook, Elise Clark, Laurence Dubensky

East Florida Division GME Research Day 2024

No abstract provided.

Type Ii Diabetes And Keto Diet In Family Medicine Clinic: A Case Report, Dante Paredes, Karos Torres, Joshua Moton

North Texas GME Research Forum 2024

The management of patients with high cardiac risk profiles who require insulin therapy for diabetes can be challenging due to the potential adverse effects of insulin on cardiovascular health. In order to achieve remission of type 2 diabetes mellitus (T2DM) and discontinue the need for insulin, weight loss has long been recognized as a valuable approach. The goal for this case was to implement dietary and lifestyle changes in a safe and efficient manner to induce remission of T2DM, without increasing the sympathetic load often associated with fully dosed ketogenic and other fasting strategies. This case report highlights the successful …

Mcardle Disease Rhabdomyolysis Precipitated By Acetazolamide For Idiopathic Intracranial Hypertension, Shahin Cyrus Owji, Vivian Paraskevi Douglas, Mohammad Pakravan, Chaow Charoenkijkajorn, Andrew G. Lee

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Full Plate Living-Teaching Kitchen: A Sustainable Approach To Employee Health, Amy M. Daniel

Doctor of Nursing Practice Scholarly Projects

Abstract

Insufficient fiber intake is a key contributor to diet-related chronic diseases (DRCD) such as obesity, hypertension, and diabetes. This evidence-based health promotion program evaluated integrating a teaching kitchen with the Full Plate Living Plan (FPL-TK) to increase daily fiber intake. Grounded in the Social Cognitive Theory, the 8-week employee health promotion program included hands-on culinary demonstrations, a structured FPL nutrition curriculum, and fiber tracking tools to help participants engage and participate in weekly health and wellness changes. The program successfully achieved high engagement rates, with 80% of participants reporting high satisfaction with the program and 100% of participants stating …

Devastating Cerebral Injury Prior To Dka Therapy -Case Report, Brittany Bare, Chandler Sapp, Evelyn Fagan, Sunil Keshwah

South Atlantic Division GME Research Day 2024

No abstract provided.

Concepts In Animal Parasitology, Chapter 62: Hirudinea (Subclass): Parasitic Leeches, Alejandro Oceguera-Figueroa, Sebastian Kvist

Concepts in Animal Parasitology

An overview of the parasitic leeches, subclass Hirudinea, including discussion of leeches as parasites, vectors, and hosts, their general morphology, reproduction, zoogeography, classification, phylogeny, medical uses, and preparation of specimens.

Chapter 62 in Concepts in Animal Parasitology, by Alejandro Oceguera-Figueroa and Sebastian Kvist. 2024. S. L. Gardner and S. A. Gardner, editors. Zea Books, Lincoln, Nebraska, United States. doi: 10.32873/unl.dc.ciap062

To Have And To Not Hold: Long-Acting Insulin For Npo Patients With Diabetes, William Hicks, Cindy Iwuagwu, Suzan Khalil, Juan Pablo Meruvia Garron, Cynthia Schwartz, Carlos Botero Suarez, Ashwini Komarla, Mustafa Kinaan

North Florida Division GME Research Day 2024

No abstract provided.

Retrospective Study: Adverse Effects Of Hyperglycemia In Nondiabetic Critically Ill Patients With Myocardial Infarction, Enkhbileg Batbileg, Jourdan Harper, Daniel Moore, Carol Wang, Sarah Barraza

Central & West Texas GME Research Day 2024

No abstract provided.

Improvement Of Diabetes Mellitus Management In A Resident-Run Clinic By Using Continuous Glucose Monitoring (Cgm), Janet Tam, Nathan Holt, Rakahn Haddadin, Ranier Rivera, Yasra Badi, Esar Dini, Andrey E. Manov

Far West Division GME Research Day 2024

No abstract provided.

Case Report: Special Considerations When Initiating Insulin In A Non-English-Speaking Patient With Diabetes: A Social Guide For New Insulin-Prescribing Residents, Jacob Uskavitch, Seth Barker

TriStar Division GME Research Day 2024

No abstract provided.

A Case Report In Hyponatremia As The First Presentation Of Stage Iv Lymphoma; An Opportunity For Earlier Diagnosis, Kathleen Rowe

TriStar Division GME Research Day 2024

No abstract provided.

Squamous Cell Carcinoma Of The Oral Cavity During Intubation, Cherry Liu, Amanda Sniadach, Michael Dinh, Christian Park, Rodd Rezvani

Far West Division GME Research Day 2024

No abstract provided.

Pregnancy Outcome In Assisted Reproductive Technology Pregnancy Complicated By 46 Day Preterm Prelabor Rupture Of Membranes, Type 2 Diabetes Mellitus And Severe Preeclampsia, A Case Report, Dana Rei Cassab, Alexis O'Connell, Maral Darya

East Florida Division GME Research Day 2024

No abstract provided.

Risks And Benefits Of Continuing Metformin During Hospitalization, Joel Speir, Sean Shearan, Kevin Trappett, Elizabeth Uba, Kenneth Krell

Continental, MidAmerica, & Mountain Divisions GME Research Day 2024

No abstract provided.

A Case Of Wernicke's Encephalopathy Due To Cannabinoid Hyperemesis, Jake Allinson, Ryan Bradbury, Paul Stanford

Continental, MidAmerica, & Mountain Divisions GME Research Day 2024

No abstract provided.

Pharmacoepidemiology Of Glp-1 Receptor Agonists, Nicholas E. Woessner

Continental, MidAmerica, & Mountain Divisions GME Research Day 2024

No abstract provided.

Disease Footprints: Understanding Basic Pathophysiology, Jeff Vasiloff, Md, Mph

OHIO Open Faculty Textbooks

Basic pathophysiology explained by Jeffrey Vasiloff, MD, MPH, Associate Clinical Professor, PA Program; Adjunct Professor, PT Program, College of Health Sciences and Professions, Ohio University Dublin Medical Campus; Physician Consultant: Ohio Association of Physician Assistants; Physician Volunteer: Franklin County & Columbus Medical Reserve Corps; Board Certification: Internal Medicine & Diabetes and Endocrinology.

Relationship Between Genotype And Disease Phenotype For Gluten-Related Disorders, Michael Roberts, Nadine Grzeskowiak, Stephen Bricher

Faculty Publications

We investigated gluten-related disorders (GRD) in intestinal biopsy-proven subjects to determine the relation between genotype (i.e., Human Leukocyte Antigen (HLA) DQ alleles) and phenotype (i.e., antibody levels and clearly defined symptoms). Subjects had known DQ genotypes, information on IgA anti-Endomysial antibodies (EMA) and/or anti-tissue Trans Glutaminase (tTG) antibodies (tTGA). Subjects also answered a survey characterizing gastrointestinal, skin, and neural symptoms. Though all were biopsy-proven, HLA genotypes included all combinations of DQ2.5, DQ2.2, DQ8, DQ7.5, DQ5, and DQ6. Subject antibody levels were proportional to the number of DQ2.5 haplotypes, and subjects with non-CD-associated haplotypes did not have positive antibody scores (despite …

Exploring The Effects Of Art Therapy Interventions On Self-Evaluations Of Food Addiction: A Randomized Control Study, Dawn Fiacco

Art Therapy | Doctoral Dissertations

Processed sugar is highly addictive and associated with chronic diseases such as obesity, type 2 diabetes, heart disease, and cancer. Often, people know that eating processed sugar has negative health consequences but continue to do so, possibly for emotional reasons. The gap between knowledge and behavior makes treating eating issues difficult. Art therapy is a nonverbal modality and could possibly circumvent usual rationalizations, making it an effective way to bridge the cognitive and emotional aspects of problematic eating. This randomized control, mixed methods study was conducted to examine whether a 7-week art directive program could help people with self-identified problematic …

Long-Term Cardiometabolic Effects Of Preconceptional And Prenatal Opioid Exposure In The Adult Offspring, Nermin Hassan Mohamed Selim Ahmed

Theses and Dissertations--Pharmacology and Nutritional Sciences

Opioid use disorder (OUD), one of the greatest public health threats in the US, requires urgent attention. In 2022, the CDC reported 107,941 overdose deaths, over 70% attributed to synthetic opioids such as fentanyl (FEN). An alarming increase in opioid use disorder (OUD) diagnoses in pregnant people resulted in a 5-fold rise in cases of neonatal opioid withdrawal syndrome (NOWS). This condition elicits sympathetic overactivity, neural hyperexcitability, and a stress reaction characterized by tachycardia and hypertension. Whether prenatal exposure to fentanyl induces cardiovascular dysfunction in the offspring remains undetermined, impeding the timely development of strategies to mitigate OUD-related health risks …

Step Squad Bundle In Older Adults With Multiple Myeloma Hospitalized For An Autologous Stem Cell Transplant, Nadya Panjwani

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Background: Multiple Myeloma (MM) is a hematological malignancy with demographic disparities. MM is a debilitating cancer mainly affecting older adults, with 66% over the age of 70. Additionally, 33% of older patients with MM are frail with weakness, fatigue, slow gait, weight loss, and malnutrition.

PICOTS: The purpose of this Doctor of Nursing (DNP) scholarly project is to implement an evidence-based practice (EBP) change consisting of a Step Squad Bundle that will identify frailty in older patients with MM hospitalized for an Autologous Stem Cell Transplant (ASCT) to reduce morbidity and mortality and increase the chances of a quality of …

Outpatient Fall Prevention In Ambulatory Adults 65 Years Old And Over, Dorothy L. Osborne-White

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Background: In the United States (U.S.), falls are the leading cause of injury among adults 65 and over, resulting in 36 million falls yearly (Moreland et al., 2020). According to the Centers for Disease Control and Prevention (CDC, 2023), one in four older adults experiences a fall each year. Falls are the world's second most prominent cause of accidental deaths (World Health Organization [WHO], 2021). Falls are the leading cause of both fatal and non-fatal injuries among older adults (Moreland et al., 2020).

Methods: A quality improvement project that included a fall bundle was implemented in a primary clinic. A …

Applying The Evidence: Taste Manipulation As A Dysphagia Management Strategy, Ross M. Westemeyer, Angela M. Dietsch, Rachel W. Mulheren

Department of Special Education and Communication Disorders: Faculty Publications

Purpose: This narrative review aims to summarize the evidence regarding taste manipulation as a dysphagia management strategy within the evidence-based practice framework, with a focus on clinical application for speech-language pathologists.

Method: First, we present background information on the physiology of taste and swallowing. A summary of research evidence on the effect of taste on swallowing is presented, followed by suggested methods for incorporating taste into swallowing evaluation and intervention. An overview of individual factors that can impact taste perception is provided. Finally, we discuss methods of clinical application and future directions for clinicians.

Conclusions: Although taste …

Action Apac: Understanding Perceptions, Attitudes And Behaviours In Obesity And Its Management Across South And Southeast Asia, Kwang Wei Tham, Asma Ahmed, Apussanee Boonyavarakul, Mariana Mercado Garcia, Miroslava Guajardo, Zubaidah Nor Hanipah, Tran Quang Nam, Nemencio A. Nicodemus, Faruque Pathan, Jack Garcia Uranga Romano, Sidartawan Soegonda, Edgardo L. Tolentino, Ambika Gopalakrishnan (A G) Unnikrishnan, Brian J. Oldfield

Ateneo School of Medicine and Public Health Publications

To identify perceptions and attitudes among people with obesity (PwO) and healthcare professionals (HCPs) toward obesity and its management in nine Asia-Pacific (APAC) countries, a cross-sectional online survey was conducted among adult PwO with self-reported body mass index of ≥25 kg/m2 (≥27 kg/m2, Singapore), and HCPs involved in direct patient care. In total, 10 429 PwO and 1901 HCPs completed the survey. Most PwO (68%) and HCPs (84%) agreed that obesity is a disease; however, a significant proportion of PwO (63%) and HCPs (41%) believed weight loss was the complete responsibility of PwO and only 43% of PwO discussed weight …

Non-Coding Rnas Involved In The Molecular Pathology Of Alzheimer’S Disease: A Systematic Review, Reynand Jay Canoy, Jenica Clarisse Sy, Christian Deo Deguit, Caitlin Bridgette Castro, Lyoneil James Dimaapi, Beatrice Gabrielle Panlaqui, Wenzel Perian, Justine Yu, John Mark Velasco, Jesus Emmanuel Sevilleja, Anna Gibson

Ateneo School of Medicine and Public Health Publications

Alzheimer’s disease (AD) is the leading cause of dementia globally, having a pathophysiology that is complex and multifactorial. Recent findings highlight the significant role of non-coding RNAs (ncRNAs), specifically microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and piwi-interacting RNAs (piRNAs) in the molecular mechanisms underlying AD. These ncRNAs are involved in critical biological processes such as cell proliferation, apoptosis, oxidative stress, amyloid-beta aggregation, tau phosphorylation, neuroinflammation, and autophagy, which are pivotal in AD development and progression. This systematic review aims to consolidate current scientific knowledge on the role of ncRNAs in AD, making it the first to encompass …

Pathways To Hypertension Control: Unfinished Journeys Of Low-Income Individuals In Malaysia And The Philippines, Benjamin Palafox, Dina Balabanova, Arianna Maever Loreche, Nafiza Mat-Nasir, Farnaza Ariffin, Mazapuspavina Md-Yasin, Mohamad Rodi Isa, Fadhlina Abd-Majid, Lia M. Palileo-Villanueva, Alicia Renedo, Maureen L. Seguin, Antonio L. Dans, Martin Mckee

Ateneo School of Medicine and Public Health Publications

Background

Reducing inequities in hypertension control among those affected in low- and middle-income countries requires person-centred health system responses based on a contextualised understanding of the choices and care pathways taken by those who rely on the services provided, particularly those from poor and marginalised communities. We examine patterns of care seeking and pathways followed by individuals with hypertension from low-income households in the Philippines and Malaysia. This study aims to fill a significant gap in the literature by analysing the stages at which individuals make decisions that may affect the successful control of their blood pressure.

Methods

This study …

Non-Alcoholic Fatty Liver Disease: Genetic Susceptibility, Shakil A. Saghir, Nicole Shams, Lianette Veliz, Saleh Alfuraih, Yadollah Omidi, Jaleh Barar, Ajay Sharma, Rais Ansari

Pharmacy Faculty Articles and Research

The prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) is increasing, particularly in individuals who consume minimal to no alcohol. Currently, NAFLD affects at least 32% of the global population. Although not all but approximately 5-10% cases of NAFLD progress to non-alcoholic steatohepatitis (NASH), a condition arising from lipotoxicity. Patients with NASH may further develop liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). However, it is important to note that progression from NAFLD to NASH and HCC is not inevitable for all patients. The pathogenesis of HCC in the context of NAFLD and NASH remains poorly understood, however, fat accumulation, often due …

Health And Lifestyle Behavioral Changes To Prevent Myocardial Infarction (Mi): Mixed Methods Approach To Understand Secondary Mi Prevention, Naila Idreesa Saghir

Global Public Health | Senior Theses

Cardiovascular diseases are the leading causes of death globally and about 200,000 individuals experience their second myocardial infarction yearly. There is a lack of understanding about how lifestyle and behavioral changes can prevent secondary myocardial infarction a year in the United States. The objective of this study is to use a mixed methods approach to understand how individuals who have made lifestyle behavioral changes to prevent their secondary myocardial infarction. Surveys and interviews consisted of questions about the participants' health behaviors and health history. Demographics, background information, and lifestyle behavioral changes were measured using Qualtrics. Valid and reliable tools such …

Exploring The Physiology Of Clostridioides Difficile: Selenium-Dependent Catabolism Of Host-Derived Nutrients, Michael A. Johnstone

Graduate Thesis and Dissertation 2023-2024

Clostridioides difficile is a bacterial pathogen that causes pseudomembranous colitis and the majority of antibiotic-associated diarrheal cases. Broad-spectrum antibiotic usage disrupts the normal gut microbiota and thereby compromises colonization resistance, the main defense against C. difficile infection. Treatment options are limited to vancomycin, fidaxomicin, and the fecal microbiota transplant. Addressing the scarcity of these therapeutics, we documented two explorations in C. difficile drug discovery: (i) evaluation of antibacterial and toxin-suppressing activity of (+)-puupehenone and similar derivatives, and (ii) clarification of a discrepancy in the hypothesized mechanism of auranofin against C. difficile. A better understanding of how C. difficile colonizes …

Bringing Awareness To The New Treatment Options For Diabetic Ketoacidosis, Raymond Alvarez, Summer Alvarez, Kristina Ledbetter, Sean Quinonez

West Florida Division GME Research Day 2024

No abstract provided.