Digital Commons Network^™

Gnnsynergy: A Multi-View Graph Neural Network For Predicting Anti-Cancer Drug Synergy, Zhifeng Hao, Jianming Zhan, Yuan Fang, Min Wu, Ruichu Cai

Research Collection School Of Computing and Information Systems

Drug combinations play very important roles in cancer therapy, as they can enhance curative efficacy and overcome drug resistance. Due to the increasing size of combinatorial space, experimental screening for all the drug combinations becomes infeasible in practice. Therefore, there is a great need to develop accurate computational approaches that can predict potential drug combinations to direct the experimental screening. In this paper, we propose a novel method called GNNSynergy to learn drug embeddings for drug synergy prediction. Given a specific cancer cell line, we propose a multi-view graph neural network framework which considers the current cell line as main …

Defending Federated Recommender Systems Against Untargeted Attacks: A Contribution-Aware Robust Aggregation Scheme, Ruicheng Liang, Yuanchun Jiang, Feida Zhu, Ling Cheng, Huiwen Liu

Research Collection School Of Computing and Information Systems

Federated recommender systems (FedRSs) effectively tackle the tradeoff between recommendation accuracy and privacy preservation. However, recent studies have revealed severe vulnerabilities in FedRSs, particularly against untargeted attacks seeking to undermine their overall performance. Defense methods employed in traditional recommender systems are not applicable to FedRSs, and existing robust aggregation schemes for other federated learning-based applications have proven ineffective in FedRSs. Building on the observation that malicious clients contribute negatively to the training process, we design a novel contribution-aware robust aggregation scheme to defend FedRSs against untargeted attacks, named contribution-aware Bayesian knowledge distillation aggregation (ConDA), comprising two key components for the …

Charge Your Clients: Payable Secure Computation And Its Applications, Cong Zhang, Liqiang Peng, Weiran Liu, Shuaishuai Li, Meng Hao, Lei Zhang, Dongdai Lin

Research Collection School Of Computing and Information Systems

The online realm has witnessed a surge in the buying and selling of data, prompting the emergence of dedicated data marketplaces. These platforms cater to servers (sellers), enabling them to set prices for access to their data, and clients (buyers), who can subsequently purchase these data, thereby streamlining and facilitating such transactions. However, the current data market is primarily confronted with the following issues. Firstly, they fail to protect client privacy, presupposing that clients submit their queries in plaintext. Secondly, these models are susceptible to being impacted by malicious client behavior, for example, enabling clients to potentially engage in arbitrage …

Application Of Machine Learning And Large Language Models In Healthcare For Data Prediction And Summarization, Chiazam Chisom Izuchukwu

College of Graduate Studies: Theses & Dissertations

This study aims to examine the use of machine learning (ML) and large language models (LLMs) in healthcare to enhance disease prediction, clinical decision-making, and information management. Five supervised ML models—Logistic Regression (LR), Support Vector Machine (SVM), Random Forest (RF), Decision Trees (DT), and Naïve Bayes (NB)—on three different computing platforms—Google Colab, Databricks, and Snowflake—were employed for disease classification. Data preprocessing included treating missing values, encoding categorical variables utilizing one-hot-encoding, feature scaling when needed, and tackling class imbalance with Synthetic Minority Over-sampling Technique (SMOTE) before an 80-20 train-test separation. Models were created with Scikit-learn (Google Collab), Spark MLlib (Databricks), and …

Machine Learning Methods For Intrusion Detection And Response In Network Security, Ayomide Oyemaja

College of Graduate Studies: Theses & Dissertations

Intrusion Detection Systems (IDS) play a crucial role in computer network security by identifying malicious activities and potential cyberattacks. This thesis combines machine learning and cybersecurity by applying Reinforcement Learning (RL) in intrusion detection and response using the NSL-KDD dataset.

We designed and implemented a Q-learning framework where an agent learns to classify network traffic over time by interacting with the environment and receiving rewards based on detection accuracy. We also look at the importance of feature selection and classification techniques and how effective they are in improving model performance, reducing the complexity of computation, and producing more desirable results. …

Enhancing Adhd Diagnosis In College Students Using Multimodal Integration Of Nicats And Iva-2 Tools, Rushmila Shabneen

College of Graduate Studies: Theses & Dissertations

This study explores enhanced methods for accurately identifying Attention Deficit Hyperactivity Disorder (ADHD) indicators in college students. ADHD, a neurodevelopmental disorder, impacts attention, impulse control, and emotional regulation, often leading to academic and social difficulties. Many students remain undiagnosed due to symptom overlap with stress and other factors. Traditional tools like the IVA-2 assess behavioral responses but may not fully capture ADHD complexity. This research integrates IVA-2 data with multimodal metrics from the Non-Intrusive Classroom Attention Tracking System (NiCATS), which monitors facial expressions, eye movements, and computer interactions. Preliminary results show that combining these tools improves ADHD detection, reduces false …

Marrying Top-K With Skyline Queries: Operators With Relaxed Preference Input And Controllable Output Size, Kyriakos Mouratidis, Keming Li, Bo Tang

Research Collection School Of Computing and Information Systems

The two most common paradigms to identify records of preference in a multi-objective setting rely either on dominance (e.g., the skyline operator) or on a utility function defined over the records' attributes (typically, using a top-k query). Despite their proliferation, each of them has its own palpable drawbacks. Motivated by these drawbacks, we identify three hard requirements for practical decision support, namely, personalization, controllable output size, and flexibility in preference specification. With these requirements as a guide, we combine elements from both paradigms and propose two new operators, ORD and ORU. We perform a qualitative study to demonstrate how they …

Performance Evaluation Of Newsql Databases In A Distributed Architecture, Zhiyao Zhang, Alan @ Ali Madjelisi Megargel, Lingxiao Jiang

Research Collection School Of Computing and Information Systems

In the last decade, application architectures have evolved drastically, moving from monolithic architectures to distributed architectures where deployment has shifted from dedicated on-premises servers to the cloud. Distributed architectures and cloud computing has enabled businesses to scale their application components across different geographical locations. While it is easy to scale the application layer, scaling its database layer that relies on traditional SQL databases is challenging and often is a common source of bottlenecks when it comes to application performance. This paper evaluates the performance characteristics between two NewSQL databases solutions, MySQL NDB Cluster vs. TIBCO ActiveSpaces IMDG. Serving as an …

Bi-Objective Dynamic Tugboat Scheduling With Speed Optimization Under Stochastic And Time-Varying Service Demands, Xiaoyang Wei, Hoong Chuin Lau, Zhe Xiao, Xiuju Fu, Xiaocai Zhang, Zheng Qin

Research Collection School Of Computing and Information Systems

With the growing emphasis on green shipping to reduce the environmental impact of maritime transportation, optimizing fuel consumption with maintaining high service quality has become critical in port operations. Ports are essential nodes in global supply chains, where tugboats play a pivotal role in the safe and efficient maneuvering of ships within constrained environments. However, existing literature lacks approaches that address tugboat scheduling under realistic operational conditions. To fill the research gap, this is the first work to propose the bi-objective dynamic tugboat scheduling problem that optimizes speed under stochastic and time-varying demands, aiming to minimize fuel consumption and manage …

Attribute-Based Encryption With Searchable Encryption, Yang Yang

Research Collection School Of Computing and Information Systems

Attribute-based encryption (ABE) with searchable encryption is a notion that inherits the advantages of both ABE (Goyal et al., 2006) and searchable encryption (SE) (Boneh et al., 2004; Boneh and Waters, 2007) mechanisms to realize secure share and search for the outsourced data. ABE creates fine-grained access control system to prevent sensitive data from being accessed by unauthorized user or external attacker (Bethencourt et al., 2007). SE generates encrypted index for outsourced data such that it can be searched by a keyword trapdoor (or token) (Shi et al., 2007; Naveed et al., 2014), where the outsourced content and search keyword(s) …

A Survey Of Multilingual Large Language Models, Libo Qin, Qiguang Chen, Yuhang Zhou, Zhi Chen, Yinghui Li, Lizi Liao, Min Li, Wanxiang Che, Philip S. Yu

Research Collection School Of Computing and Information Systems

Multilingual large language models (MLLMs) leverage advanced large language models to process and respond to queries across multiple languages, achieving significant success in polyglot tasks. Despite these breakthroughs, a comprehensive survey summarizing existing approaches and recent developments remains absent. To this end, this paper presents a unified and thorough review of the field, highlighting recent progress and emerging trends in MLLM research. The contributions of this paper are as follows. (1) Extensive survey: to our knowledge, this is the pioneering thorough review of multilingual alignment in MLLMs. (2) Unified taxonomy: we provide a unified framework to summarize the current progress …

Ai Characterisations And Their Legal Implications, Jerrold Tsin Howe Soh

Research Collection Yong Pung How School Of Law

This chapter examines the difficult legal characterisation problems that artificially intelligent systems raise and explores how different characterisations of artificial intelligence (AI) shape practical legal outcomes. Three reasons are offered for the legal difficulty with characterising AI. First, answers to characterisation problems are inherently subjective and perspective-driven, particularly when the subject is an intangible technological system. Second, AI technology is especially difficult to define since the field typically proceeds on inexact anthropomorphic metaphors. Third, AI characterisation problems raise difficult sub-problems, particularly in determining how autonomous an AI system is. The chapter thus argues that a range of plausible AI characterisations …

Sogar: Self-Supervised Spatiotemporal Attention-Based Social Group Activity Recognition, Naga Venkata Sai Raviteja Chappa, Pha Nguyen, Alexander H. Nelson, Han-Seok Seo, Xin Li, Page Daniels Dobbs, Khoa Luu

Electrical Engineering and Computer Science Faculty Publications and Presentations

Social group activity recognition is crucial for various applications including surveillance, human-robot interaction, and behavioral analysis. Current approaches often require extensive manual annotations and rely heavily on pre-trained detectors, limiting their practical applications. Additionally, existing methods struggle to effectively model long-term spatiotemporal relationships in group activities. This paper introduces a novel approach to Social Group Activity Recognition (SoGAR) using Self-supervised Transformers network that can effectively utilize unlabeled video data. To extract spatio-temporal information, we create local and global views with varying frame rates. Our self-supervised objective ensures that features extracted from contrasting views of the same video are consistent across …

Last Digit Tendency: Lucky Number And Psychological Rounding In Mobile Transactions, Hai Wang, Tian Lu, Yingjie Zhang, Yue Wu, Yiheng Sun, Jingran Dong, Wen Huang

Research Collection School Of Computing and Information Systems

The distribution of digits in numbers obtained from different sources reveals interesting patterns. The well-known Benford’s law states that the first digits in many real-life numerical data sets have an asymmetric, logarithmic distribution in which small digits are more common; this asymmetry diminishes for subsequent digits, and the last digit tends to be uniformly distributed. In this paper, we investigate the digit distribution of numbers in a large mobile transaction data set with 835 million mobile transactions and payments made by approximately 460,000 users in more than 300 cities. Although the first digits of the numbers in these mobile transactions …

Normalizing Images In Various Weather And Lighting Conditions Using Colorpix2pix Generative Adversarial Network, Sanjida Tasnim, Ashif Mahmud Mostafa, Azmain Morshed, Namreen Shaiyaz, Shakib Mahmud Dipto, Saad Aloteibi, Mohammad Ali Moni, Md. Golam Rabiul Alam, Md. Ashraful Alam

Computer Science Faculty Publications

Autonomous vehicles (AVs) are widely regarded as the future of transportation due to their tremendous benefits and user comfort. However, the AVs have been struggling with very crucial challenges, such as achieving reliable accuracy in object detection as well as faster computation required for quick decision-making. In recent years, perception systems in driverless cars have been significantly enhanced, mainly due to advances in deep-learning-based object detection systems. However, these perception systems are still heavily affected by environmental variables, such as changes in illumination, refractive interference, and adverse weather conditions, which may compromise their reliability and safety. This research proposes an …

Coming Back Differently: An Exploratory Case Study Of Near Death Experiences Of Webpages, Lesley Frew, Michael L. Nelson, Michele Weigle

Computer Science Faculty Publications

In this case study, we use web archives to analyze 8,824 webpages that were taken offline and subsequently put back online, thus experiencing a “near death experience.” We enumerate the stages of a webpage’s near death experience, including the change from a successful HTTP status code to non-successful and back, the intermediate stage with markers such as an under construction banner, and an analysis of how the pages came back differently.

Insights In Adaptation: Examining Self-Reflection Strategies Of Job Seekers With Visual Impairments In India, Akshay Kolgar Nayak, Yash Prakash, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok

Computer Science Faculty Publications

Significant changes in the digital employment landscape, driven by rapid technological advancements and the COVID-19 pandemic, have introduced new opportunities for blind and visually impaired (BVI) individuals in developing countries like India. However, a significant portion of the BVI population in India remains unemployed despite extensive accessibility advancements and job search interventions. Therefore, we conducted semi-structured interviews with 20 BVI persons who were either pursuing or recently sought employment in the digital industry. Our findings reveal that despite gaining digital literacy and extensive training, BVI individuals struggle to meet industry requirements for fulfilling job openings. While they engage in self-reflection …

Geometric Gnns For Charged Particle Tracking At Gluex, Ahmed Hossam Mohammed, Kishansingh Rajput, Simon Taylor, Denis Furletov, Sergey Furletov, Malachi Schram

Computer Science Faculty Publications

Nuclear physics experiments are aimed at uncovering the fundamental building blocks of matter. The experiments involve high-energy collisions that produce complex events with many particle trajectories. Tracking charged particles resulting from collisions in the presence of a strong magnetic field is critical to enable the reconstruction of particle trajectories and precise determination of interactions. It is traditionally achieved through combinatorial approaches that scale worse than linearly as the number of hits grows. Since particle hit data naturally form a point cloud and can be structured as graphs, graph neural networks (GNNs) emerge as an intuitive and effective choice for this …

A Bibliographic And Topic Modeling Analysis Of The P-Adic Theory Literature Using Latent Dirichlet Allocation, Humberto Llinás, Ismael Gutiérrez, Anselmo Torresblanca, Javier De La Hoz, Brian Llinás

Computer Science Faculty Publications

P-adic analysis, introduced by Kurt Hensel in the early 20th century, has developed into a fundamental area of mathematical research with broad applications in number theory, algebraic geometry, and mathematical physics. This study aims to examine the thematic evolution and scholarly impact of p-adic research through a comprehensive topic modeling and bibliometric analysis. Using classical bibliometric techniques (e.g., performance analysis, co-authorship, and co-citation networks) combined with Latent Dirichlet Allocation (LDA), we analyzed 7388 peer-reviewed documents published between 1965 and 2024. The computational workflow was conducted using R (version 4.4.1) and VOSviewer (version 1.6.20), which enabled the identification of 20 distinct …

Quickque: Enabling Quick Access To Information In User Reviews For Screen Reader Users, Mohan Sunkara, Akshay Kolgar Nayak, Sandeep Kalari, Yash Prakash, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok

Computer Science Faculty Publications

Efficiently perusing online customer reviews is presently challenging for blind users, who rely on a screen reader that supports predominantly one-dimensional narration of content via keyboard shortcuts. To address this, with restaurant reviews as seminal case study, we developed QuickCue, a browser extension prototype that enables screen reader users to quickly obtain the positives and negatives regarding different aspects of a restaurant (e.g., food quality, hygiene, ambiance), without having to sift through numerous reviews containing redundant information. At its core, QuickCue utilizes a large language model to perform aspect and sentiment-based joint classification of reviews to group them based on …

Adversarially Attacking Graph Properties And Sparsification In Graph Learning, Chunjiang Zhu, Blake Gaines, Jing Deng, Jinbo Bi

Computer Science Faculty Publications

Graph neural networks and graph transformers explicitly or implicitly rely on fundamental properties of the underlying graph, such as spectral properties and shortest-path distances. However, it is still not clear how these graph properties are vulnerable to adversarial attacks and what impacts this has on the downstream graph learning. Moreover, while graph sparsification has been used to improve computational cost of learning over graphs, its susceptibility to adversarial attacks has not been studied. In this paper, we study adversarial attacks on graph properties and graph sparsification and their impacts on downstream graph learning, paving the way for how to protect …

Adapting Online Customer Reviews For Blind Users: A Case Study Of Restaurant Reviews, Mohan Sunkara, Akshay Kolgar Nayak, Sandeep Kalari, Yash Prakash, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok

Computer Science Faculty Publications

Online reviews have become an integral aspect of consumer decision-making on e-commerce websites, especially in the restaurant industry. Unlike sighted users who can visually skim through the reviews, perusing reviews remains challenging for blind users, who rely on screen reader assistive technology that supports predominantly one-dimensional narration of content via keyboard shortcuts. In an interview study, we uncovered numerous pain points of blind screen reader users with online restaurant reviews, notably, the listening fatigue and frustration after going through only the first few reviews. To address these issues, we developed QuickCue assistive tool that performs aspect-focused sentiment-driven summarization to reorganize …

Deepssetracer 2.0: Improved Deep Learning Model Performance For Protein Secondary Structure Segmentation From Cryo-Em Maps, Bryan Hawickhorst, Thu Nguyen, Willy Wriggers, Jiangwen Sun, Jing He

Computer Science Faculty Publications

DeepSSETracer is a method for segmenting protein secondary structure from medium-resolution (5-10Å) cryogenic electron microscopy (cryo-EM) density maps. We conducted experiments and ablation studies to examine the effects of normalization methods, max-pooling, activation functions, and loss calculation region on DeepSSETracer. By combining multiple technical improvements, the performance of the new version, DeepSSETracer 2.0, was significantly enhanced compared to DeepSSETracer 1.1. On a set of 77 test cases, the weighted average per-voxel F1 score increased from 62.1% to 70.3% for helix detection, and from 47.8% to 62.5% for β-sheet detection. While each of the five modifications in the network enhanced the …

From Philosophy To Nlu: Evolving Definitions Of Research Hypotheses, Jian Wu, Sarah Rajtmajer

Computer Science Faculty Publications

Over the past decades, alongside advancements in natural language processing, significant attention has been paid to training models to automatically extract, understand, test, and generate hypotheses in open and scientific domains. However, interpretations of the term hypothesis for various natural language understanding (NLU) tasks have migrated from traditional definitions in the natural, social, and formal sciences. Even within NLU, we observe differences defining hypotheses across literature. In this paper, we overview and delineate various definitions of hypothesis. Especially, we discern the nuances of definitions across recently published NLU tasks. We highlight the importance of well-structured and well-defined hypotheses, particularly as …

Can Llms Beat Humans On Discerning Human-Written And Llm-Generated Science News, Dominik Soós, Meng Jiang, Jian Wu

Computer Science Faculty Publications

Science news is increasingly important in connecting scientists and the public by sharing discoveries and innovations. With the rise of large language models (LLMs), there is potential to automate science news creation, but concerns exist about the quality of LLM-generated news versus human-written news. This paper explores whether LLMs can outperform humans in distinguishing between human-written and LLM-generated news. Inspired by the Chain-of-Thought prompting method, we designed a simple yet effective variant called Guided Few-shot (GFS), which encodes the characteristics of news of two types with examples. Our experiments indicated that GFS with just a single example effectively boosted the …

Benchmarking And Improving Foundation Model Dietary Estimates From Meal Images, Yongcheng Mu, Jiangwen Sun, Jing He

Computer Science Faculty Publications

Accurate quantifying dietary contents, such as calories, proteins, carbohydrates, and fats, from an image of a meal plate is vital for managing diabetes. Recently, Large Multimodal Models (LMMs) have excelled in complex vision-language tasks due to their use of very large, highly diverse data. This study benchmarked the use of seven LMMs that include full and lightweight models of GPT, Gemini, and Llama for nutrition estimation based on Google's Nutrition5k dataset and our own phone-collected DonateAndLearn dataset. We analyzed the performance of LMMs and the RGB-D fusion model, in which the RGB-D model was specifically trained using Nutrition5k data. On …

Energy-Based Deep Incomplete Multi-View Clustering, Ziyu Wang, Yiming Du, Rui Ning, Lusi Li

Computer Science Faculty Publications

Incomplete multi-view clustering (IMVC) deals with real-world scenarios where certain views are partially missing, posing significant challenges to effective clustering. Most existing IMVC approaches face a trade-off: imputation-free methods suffer from information bias and imbalance, while full-imputation methods risk introducing and propagating noise. To overcome these limitations, we propose Energy-Based Deep Incomplete Multi-View Clustering (Energy-DIMC), a novel selective-imputation framework that leverages energy-based models (EBMs) to guide reliable imputations and robust clustering. EBMs assess data compatibility by assigning lower energy to more coherent structures, effectively modeling complex inter-view and inter-sample dependencies. Inspired by EBMs, Energy-DIMC integrates four key components: 1) a …

Understanding Pii Leakage In Large Language Models: A Systematic Survey, Shuai Cheng, Zhao Li, Shu Meng, Mengxia Ren, Haitao Xu, Shuai Hao, Chuan Yue, Fang Zhang

Computer Science Faculty Publications

Large Language Models (LLMs) have demonstrated exceptional success across a variety of tasks, particularly in natural language processing, leading to their growing integration into numerous facets of daily life. However, this widespread deployment has raised substantial privacy concerns, especially regarding personally identifiable information (PII), which can be directly associated with specific individuals. The leakage of such information presents significant real-world privacy threats. In this paper, we conduct a systematic investigation into existing research on PII leakage in LLMs, encompassing commonly utilized PII datasets, evaluation metrics, and current studies on both PII leakage attacks and defensive strategies. Finally, we identify unresolved …

Delivery Of Medical Supplies To Remote Locations Via Unmanned Aerial Vehicles: Approaches, Challenges, And Solutions, Meshari Aljohani, Ravi Mukkamala, Stephanie Olariu

Computer Science Faculty Publications

Unmanned Aerial Vehicles (UAVs) are becoming more important in improving healthcare logistics, in particular due to their cost effectiveness, minimized risk, and versatile operational capabilities. This study explores the deployment of autonomous UAVs to deliver medical supplies to remote areas. Advances in ledger technology, smart contracts, and machine learning have transformed tasks previously managed by human teams or manually controlled UAVs into fully autonomous missions. We present a comprehensive analysis of the challenges and initial solutions vital for the effective use of autonomous UAVs in the delivery of medical supplies. In addition, we propose a machine-learning model to optimize UAV …

Nexus: Network Exploration For Exploiting Unsafe Sequences In Multi-Turn Llm Jailbreaks, Javad Rafiei Asl, Sidhant Narula, Mohammad Ghasemigol, Eduardo Blanco, Daniel Takabi

Computer Science Faculty Publications

Large Language Models (LLMs) have revolutionized natural language processing, yet remain vulnerable to jailbreak attacks—particularly multi-turn jailbreaks that distribute malicious intent across benign exchanges, thereby bypassing alignment mechanisms. Existing approaches often suffer from limited exploration of the adversarial space, rely on hand-crafted heuristics, or lack systematic query refinement. We propose NEXUS (Network Exploration for eXploiting Unsafe Sequences), a modular framework for constructing, refining, and executing optimized multi-turn attacks. NEXUS comprises: (1) ThoughtNet, which hierarchically expands a harmful intent into a structured semantic network of topics, entities, and query chains; (2) a feedback-driven Simulator that iteratively refines and prunes these chains …