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Synthesis And Study Of Stable Organic Radicals For Mri Contrast Agents And New Materials, Sabina Dhakal Dec 2025

Synthesis And Study Of Stable Organic Radicals For Mri Contrast Agents And New Materials, Sabina Dhakal

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The first part of this dissertation focuses on the design, synthesis, and characterization of a thermally robust S =1/2 phototetrazolinyl monoradical and the development of synthetic methodologies for a high-spin (S = 1) phototetrazolinyl diradical. Electrochemical studies of the phototetrazolium cation (precursor to the monoradical) revealed a remarkably narrow electrochemical band gap (Ecell ≈ 0.82 V), suggesting promising electrical conductivity. Thermal analysis of the monoradical demonstrated excellent stability, with the onset of decomposition at 232 °C. Building on the excellent thermal stability and promising properties for electrical conductivity of the monoradical, we developed two condensation-based synthetic routes that provide viable …


Method Optimisation And Environmental Analysis Of Methanesulfonic Acid (Msa) In Rainwater By Ion Chromatography, Thomas Levett Dec 2025

Method Optimisation And Environmental Analysis Of Methanesulfonic Acid (Msa) In Rainwater By Ion Chromatography, Thomas Levett

The Plymouth Student Scientist

This research optimised a method of analysis for methanesulfonic acid (MSA) alongside common inorganic anions using ion chromatographic (IC) apparatus developed at the University of Plymouth. The aim was to assess whether MSA could be more easily and routinely monitored alongside common rainwater anions. The method’s analytical quality was evaluated through each development stage of the research and its limitations found. Historical rainwater samples collected at Penlee Point, Plymouth, UK (2015–2018) were also used for testing. The method successfully provided detectable ranges of MSA between 0.001 – 5 mg/L for F-, Cl-, NO2-, Br …


Isolation, Chemical Characterization, And In-Vitro Cytotoxic Evaluation Of Novel Polar Flavonoids From Chromolaena Leivensis, Matthew Tohatsu Tetteh Dec 2025

Isolation, Chemical Characterization, And In-Vitro Cytotoxic Evaluation Of Novel Polar Flavonoids From Chromolaena Leivensis, Matthew Tohatsu Tetteh

Electronic Theses and Dissertations

This study focuses on isolation, chemical characterization, and in-vitro cytotoxic evaluation of novel polar flavonoids from chromolaena leivensis. A 95% ethanolic extract of c. leivensis shipped by Prof. Ruben Torrenegra from University of Applied and Environmental Sciences, Bogota, Colombia, was dissolved in 1:1 methanol/chloroform mixture and its purity analyzed by TLC. The sample was eluted with toluene/methanol in an increasing order of polarity on silica gel, resulting in 49 fractions labelled CLA1 to CLA49. Among these fractions, CLA10 (1) and CLA19 (2) obtained yellow and white crystals. They were analyzed by GCMS, IR, and …


Exploring Halogen Bonding Interactions In Cocrystals And Deep Eutectic Solvents, Madhushi Bandara Dec 2025

Exploring Halogen Bonding Interactions In Cocrystals And Deep Eutectic Solvents, Madhushi Bandara

All Dissertations

Halogen bonding is a noncovalent intermolecular interaction analogous to hydrogen bonding that occurs between an electrophile and a nucleophile. This is often observed in compounds containing heavy halogens such as iodine and bromine. When these halogens are covalently bonded to another atom or molecule, preferably to an electron-withdrawing moiety, an electrophilic region called a sigma hole is created on the halogen atom on the extension of the covalent bond.

The first study of this dissertation presents a comprehensive characterization of eight newly synthesized triiodide salts using single-crystal X-ray diffraction, powder X-ray diffraction, thermal analysis (DSC and TGA), and Raman spectroscopy. …


Novel Radical Chemistry Of Electron-Rich Double Bonds, Claire Allyson Beard Dec 2025

Novel Radical Chemistry Of Electron-Rich Double Bonds, Claire Allyson Beard

Graduate Theses and Dissertations

This work delves into the reactivity of nucleophilic N-heterocyclic carbenes (NHCs) and their ability to form electron-rich alkene intermediates, which can undergo various chemical transformations depending on the nature of the electrophile. Initial reports by Hahn disclosed the NHC promoted radical nature of electron-rich N,N’-benzyltetraazafulvalenes, which led to 2,2’- biimidazoles. We found that N-aryl substituted pyridinium salts also underwent rapid a similar NHC promoted dimerization when exposed to a base, producing 2,2’-bipyridyls. This is likely due to the adept radical nature of the bipyridinylidene intermediate for C-Naryl bond scission. We have also uncovered an unprecedented C-N bond scission of Breslow-like …


Synthesis Of Phenyl-Substituted Zinc Dipyrrin Photosensitizer For Carbon Dioxide Reduction, Stephen Ankomah Dec 2025

Synthesis Of Phenyl-Substituted Zinc Dipyrrin Photosensitizer For Carbon Dioxide Reduction, Stephen Ankomah

Electronic Theses and Dissertations

The release of CO₂ from fossil fuel combustion drives the need for its conversion into more sustainable options like CO and CH₄ via photocatalytic reduction. This process requires a catalyst, sensitizer, and electron donor. Zinc dipyrrin-based complexes are promising photosensitizers, offering an alternative to expensive, rare-metal-based systems. Most first-row transition metal dipyrrin compounds have short excited-state lifetimes due to rapid nonradiative decay, but Zn(II) dipyrrin complexes stand out. With a d¹⁰ configuration, they lack deactivating ligand field states and can access long-lived triplet states through a charge-separated intermediate. A phenyl-substituted Zn(II) dipyrrin complex was synthesized and studied using NMR to …


Divergent Responses Of Branched-Chain And Straight-Chain Lipid Membranes To Butanol Stress Revealed By All-Atom Molecular Dynamics Simulations, Joshua Olaf Aggrey Dec 2025

Divergent Responses Of Branched-Chain And Straight-Chain Lipid Membranes To Butanol Stress Revealed By All-Atom Molecular Dynamics Simulations, Joshua Olaf Aggrey

Electronic Theses and Dissertations

Membrane integrity under chemical stress is critical to cellular survival and industrial microbial bioproduction, yet the molecular basis of bilayer resilience remains poorly understood. Using all-atom molecular dynamics simulation, we compare the effect of increasing concentrations of 1‑butanol on membranes composed of straight-chain (1,2-dipalmitoyl-sn-glycero-3-phosphocholine, DPPC) and branched-chain (1-anteiso-palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine, APPC) lipids, which differ in the point of attachment of a single methyl group. In the absence of butanol, both membranes exhibit well-ordered architectures consistent with experimental benchmarks; however, under increasing solvent stress, their behaviors diverge markedly. DPPC membranes display gradual thinning, modest area per lipid …


Cosmetic Surgery And Physiological Disorder: You Should Talk To Someone About Your Unwinding Anxiety, Mona Muzammil, Washain Muzammil Dec 2025

Cosmetic Surgery And Physiological Disorder: You Should Talk To Someone About Your Unwinding Anxiety, Mona Muzammil, Washain Muzammil

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Body dysmorphic disorder is a mental health condition in which you can't stop thinking about one or more perceived defects or flaws in your appearance — a flaw that appears minor or can't be seen by others. But you may feel so embarrassed, ashamed and anxious that you may avoid many social situations.

When you have body dysmorphic disorder, you intensely focus on your appearance and body image, repeatedly checking the mirror, grooming or seeking reassurance, sometimes for many hours each day. Your perceived flaw and the repetitive behaviors cause you significant distress and impact your ability to function in …


Ring-Opening And Monofunctionalization Study On Spiro Cyclic Aminals And N, O-Acetals System Via Nitrogen-Centered Radical Intermediates, Chujun Zhou Dec 2025

Ring-Opening And Monofunctionalization Study On Spiro Cyclic Aminals And N, O-Acetals System Via Nitrogen-Centered Radical Intermediates, Chujun Zhou

Graduate Theses and Dissertations

The nitrogen-centered radical has been drawing increasing attention among researchers. Radical polarity is one of the key factors in studying nitrogen-centered radicals’ reactivity, and the functional groups attached to the nitrogen atom are of vital importance. Among different types of nitrogen-centered radicals, aminium radical and metal aminium radical are electrophilic due to the positive charge on the intermediate. The sulfonamide radical, amidyl radical, and cyanide amine radical are also electrophilic since the nitrogen is adjacent to electron electron-withdrawing group. The neutral amino radical, iminyl radical, masked nitrogen radical are nucleophilic because of the electron-donating groups. After classifying the nitrogen-centered radical, …


Terrestrial And Lacustrine Organic Matter Biomolecular Transformations Via Thermal Maturation And Oxidative Degradation, Louis Connor Bondurant Dec 2025

Terrestrial And Lacustrine Organic Matter Biomolecular Transformations Via Thermal Maturation And Oxidative Degradation, Louis Connor Bondurant

Chemistry & Biochemistry Theses & Dissertations

The most abundant source of fossil fuel-forming kerogen on Earth is classified as Type II kerogen, believed to originate from marine biomass. However, a significant amount of lacustrine and terrigenous carbon is transported to the ocean through fluvial discharge. Less than half of the exported organic carbon is observed in coastal regions and the open ocean. There is a great need for an explanation of what is happening to this organic carbon during transport and deposition. Traditionally, the marine organic matter in coastal regions accumulates to eventually be buried and transformed into petroleum over millions of years due to its …


Biocompatible And Antibacterial Pcl-Tio2@Ag/Γ-Cd Mof Nanocomposite Coating For Corrosion Resistance Of Magnesium Alloy In Simulated Body Fluid, Sara Dehghan-Chenar, Hamid R. Zare, Zahra Mohammadpour, Maryam Sadat Mirbagheri-Firoozabad Nov 2025

Biocompatible And Antibacterial Pcl-Tio2@Ag/Γ-Cd Mof Nanocomposite Coating For Corrosion Resistance Of Magnesium Alloy In Simulated Body Fluid, Sara Dehghan-Chenar, Hamid R. Zare, Zahra Mohammadpour, Maryam Sadat Mirbagheri-Firoozabad

Journal of Electrochemistry

Magnesium alloys are promising candidates for bio-implant applications due to their biodegradability and biocompatibility. However, their rapid corrosion remains a critical limitation. This study presents the development of a multifunctional nanocomposite coating designed to enhance the corrosion resistance and antibacterial properties of magnesium alloy implants. The coating comprised γ-cyclodextrin metal-organic frameworks (γ-CD MOFs) decorated with TiO2@Ag core-shell nanoparticles, embedded in a polycaprolactone (PCL) matrix. Immersion tests in a simulated body fluid (SBF) revealed an initially higher corrosion rate for the PCL-TiO2@Ag/γ-CD MOF coating compared to the coating without TiO2@Ag nanoparticles; however, it demonstrated significant …


Exploring Inorganic And Organometallic Chemistry, W. Christopher Boyd Phd Nov 2025

Exploring Inorganic And Organometallic Chemistry, W. Christopher Boyd Phd

MSL Academic Endeavors eBooks

This textbook, Exploring Inorganic and Organometallic Chemistry, covers the fundamentals of inorganic and organometallic chemistry for undergraduate and graduate students. Both theories of structure and bonding and reaction chemistry are covered, with applications to the catalysis of organic reactions, biochemistry, and drug design. A modular approach allows for basic materials of each chapter to be covered in an undergraduate course, with more advanced material suitable for M.S. and Ph.D. students."


Novel Eco-Friendly Synthesis Of Coo Nps: Evaluation Of Their Diode Laser-Enhanced Inhibitory Activity Through Combined In Silico And In Vitro Approaches., Arshad Mahdi Hamad, Sahar Naji Rashid Nov 2025

Novel Eco-Friendly Synthesis Of Coo Nps: Evaluation Of Their Diode Laser-Enhanced Inhibitory Activity Through Combined In Silico And In Vitro Approaches., Arshad Mahdi Hamad, Sahar Naji Rashid

Karbala International Journal of Modern Science

In our study, for the first time worldwide, to the best of our knowledge, cobalt oxide nanoparticles (CoO NPs) were synthesized using naringin (Nar) extracted from citrus peels. The properties of the prepared Nar-CoO NPs were studied using field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDX), ultraviolet-visible (UV-Vis), X-ray diffraction (XRD), and Fourier transform infrared (FTIR) spectroscopy. All the test results demonstrated the efficiency and success of the nanofabrication process. The solution was then exposed to three types of diode lasers: red (650 nm), green (532 nm), and blue (405 nm). The purpose of this study was …


Postmortem Vitreous Humor As An Alternative Matrix To Peripheral Blood For Benzodiazepine Detection, Sara Bussey Nov 2025

Postmortem Vitreous Humor As An Alternative Matrix To Peripheral Blood For Benzodiazepine Detection, Sara Bussey

Honors Theses

Benzodiazepines are commonly prescribed secondary drugs of abuse that cause Central Nervous System depression through the neurotransmitter gamma aminobutyric acid. While not commonly fatal on their own, benzodiazepines have a minor risk for physical dependence and abuse. They also can have cumulative effects with other medications that can lead to overdose situations; thus, they are considered secondary drugs of abuse. While peripheral blood is considered the standard for xenobiotic detection in postmortem forensic toxicology, it is important to consider the validity of alternative matrices that could be analyzed in the event that blood was not available due to circumstances like …


Synthesis And Characterization Of Eco-Engineered Hollow Fe2o3/Carbon Nanocomposite Spheres: Evaluating Structural, Optical, Antibacterial, And Lead Adsorption Properties, Islam Gomaa, Nikita Yushin, Mekki Bayachou, Vojislav Stani´, Inga Zinicovscaia Nov 2025

Synthesis And Characterization Of Eco-Engineered Hollow Fe2o3/Carbon Nanocomposite Spheres: Evaluating Structural, Optical, Antibacterial, And Lead Adsorption Properties, Islam Gomaa, Nikita Yushin, Mekki Bayachou, Vojislav Stani´, Inga Zinicovscaia

Chemistry Faculty Publications

This work presents a facile mechano-thermal route for the synthesis of carbon-decorated, hollow, mesoporous alpha-Fe2O3 microspheres. Comprehensive characterization (XRD, XPS, FT-IR, SEM/EDX, TGA, zeta-potential) confirmed the formation of phase-pure hematite with nanoscale crystallites (similar to 19 nm), substantial residual surface carbon (similar to 40 wt%) consistent with Fe-O-C linkages, and a positive surface charge (+15.9 mV). The hierarchical hollow/mesoporous architecture enables fast ion transport and provides extensive interior binding sites, resulting in rapid Pb(II) uptake that reaches 92% removal in approximate to 15 min at pH 5.0. The adsorption follows a Langmuir isotherm (q(max) approximate to 70.6 mg/g) and pseudo-second-order …


Multiplexed Integrin Detection And Cancer Cell Classification Using Multicolor Gap-Enhanced Gold Nanorods And Machine Learning Algorithm, Suprava Shah, Reed Youngerman, Alberto Luis Rodriguez-Nieves, Mitchell Lee Taylor, William Rodney Bantom, David Thompson, Jingyi Chen, Yongmei Wang, Xiaohua Huang Nov 2025

Multiplexed Integrin Detection And Cancer Cell Classification Using Multicolor Gap-Enhanced Gold Nanorods And Machine Learning Algorithm, Suprava Shah, Reed Youngerman, Alberto Luis Rodriguez-Nieves, Mitchell Lee Taylor, William Rodney Bantom, David Thompson, Jingyi Chen, Yongmei Wang, Xiaohua Huang

Chemistry & Biochemistry Faculty Publications and Presentations

Integrins, cell-surface adhesion receptors involved in tumor progression, invasion, and metastasis, serve as crucial biomarkers for cancer diagnosis and therapeutic targeting. Multiplexed detection of integrins and cancer cell classification at the single-cell level allows for comprehensive profiling, facilitating precise identification and categorization of tumor cells that are heterogeneous in integrin expression and cell subtype. In this study, we developed a five-plex detection platform and demonstrated integrin profile for cancer cell classification leveraging surface-enhanced Raman scattering (SERS) with gap-enhanced gold nanorods (GENRs) in conjunction with advanced computational analysis. Specifically, we synthesized GENRs bearing five distinct Raman nanotags, each producing a unique …


Analysis Of An Effective Training Curriculum: Solutions Toincrease Participants' Interest In Training Teachingmaterials, Maulidya Husnul Khatimah, Yoto Yoto Nov 2025

Analysis Of An Effective Training Curriculum: Solutions Toincrease Participants' Interest In Training Teachingmaterials, Maulidya Husnul Khatimah, Yoto Yoto

Jurnal Pendidikan Sains

This research is important because it analyzes the curriculum as a primary tool for generating and maintaining participant interest. Curricula that are irrelevant, monotonous, or misaligned with participant needs are often the main causes of low motivation and participation. Furthermore, this research encourages the exploration and implementation of more innovative teaching methods and materials in training curricula. External pressure in the form of demands or instructions, rather than internal motivation, drives most training activities. This can reduce engagement and learning effectiveness. To overcome this, training institutions need to design programs that are relevant, flexible, and able to encourage participants' intrinsic …


Augmented Reality-Assisted E-Module On Temperature Andheat Content (Emarks), Tetri Sabrina, Ika Mustika Sari, Dedi Sasmita Nov 2025

Augmented Reality-Assisted E-Module On Temperature Andheat Content (Emarks), Tetri Sabrina, Ika Mustika Sari, Dedi Sasmita

Jurnal Pendidikan Sains

Temperature and heat content (calor) material in physics often involves concepts and phenomena that are difficult to observe directly or are abstract (such as energy transfer, particle movement, and changes in state). EMARKS (AR-based E-modules) are important because Augmented Reality (AR) allows the visualization of these abstract concepts in the form of interactive 3D models in the user's real environment. This helps students understand the concepts more concretely and easily. The development of E-modules is an innovation in learning media that is relevant to the demands of the digital era and the needs of modern students. The use of advanced …


The Effect Of Guided Inquiry Model With Deep Learningapproach On Student’S Hots In Elements, Compounds,And Mixtures At Junior High School, Friska Pakpahana, Retno Dwi Suyanti Nov 2025

The Effect Of Guided Inquiry Model With Deep Learningapproach On Student’S Hots In Elements, Compounds,And Mixtures At Junior High School, Friska Pakpahana, Retno Dwi Suyanti

Jurnal Pendidikan Sains

The current education curriculum places a strong emphasis on developing HOTS skills (such as analyzing, evaluating, and creating) to prepare students for the challenges of the 21st century. School learning often focuses on lower-level cognitive domains (memorizing and understanding). This research seeks to address this gap by offering a potentially effective learning model. The guided inquiry model positions students as active participants in learning, encouraging them to investigate, discover, and formulate concepts independently with teacher guidance. This strongly supports the development of critical thinking and problem-solving skills. Therefore, this study aims to analyze the effect of the guided inquiry model …


Development Of Problem-Based Learning Worksheet Toenhance Ecoliteracy: Human Impact On Ecosystem, Ulina M.S. Simangunsong, B. Manurung, Martina Asiati Napitupulu Nov 2025

Development Of Problem-Based Learning Worksheet Toenhance Ecoliteracy: Human Impact On Ecosystem, Ulina M.S. Simangunsong, B. Manurung, Martina Asiati Napitupulu

Jurnal Pendidikan Sains

Ecoliteracy (ecological literacy) is an individual's ability to understand basic ecological principles and make environmentally responsible decisions. Improving ecoliteracy is a crucial foundation for realizing Education for Sustainable Development (ESD), which prepares students to become proactive citizens in protecting the environment. The problem-based learning model helps students learn on their own by using real-world environmental cases to get them to think critically and solve problems. Therefore, this research aims to determine the effectiveness of using problem-based learning worksheets to enhance the ecoliteracy of seventh-grade students. The development model used is 4-D. The research instruments include expert validation forms for subject, …


Development Of E-Lkpd Assisted By Phet Colorado Basedon Discovery Learning: Critical Thinking Skills On Lightmaterial At Junior High School, Flora Yani Saragih, Pintor Simamora Nov 2025

Development Of E-Lkpd Assisted By Phet Colorado Basedon Discovery Learning: Critical Thinking Skills On Lightmaterial At Junior High School, Flora Yani Saragih, Pintor Simamora

Jurnal Pendidikan Sains

Critical thinking is necessary for 21st-century pupils, but PISA data suggest that Indonesian students, especially junior high school students, lack it. The junior high science/physics light material is abstract and involves in-depth reasoning (reflection, refraction, and shadow generation). Without critical thinking, kids memorize formulas or notions without analyzing real phenomena. Discovery learning involves pupils discovering concepts via observation and experimentation. Critical thinking requires initiative, exploration, and reasoning, which these foster. Therefore, this study aims to develop E-LKPD based on Discovery Learning assisted by an interactive simulation of PhET Colorado to strengthen the critical thinking skills of grade VIII students on …


Guided Inquiry Learning Assisted By Crossword Puzzlemedia: Student Scientific Literacy And Critical Thinkingability For Middle School, Agis Putri Niswa, Mariati Purnama Simanjuntak, Ramlan Silaban, Fauziyah Harahap, Ridwan Abdullah Sani Nov 2025

Guided Inquiry Learning Assisted By Crossword Puzzlemedia: Student Scientific Literacy And Critical Thinkingability For Middle School, Agis Putri Niswa, Mariati Purnama Simanjuntak, Ramlan Silaban, Fauziyah Harahap, Ridwan Abdullah Sani

Jurnal Pendidikan Sains

Scientific literacy and critical thinking skills are two fundamental competencies that students need in the 21st century. Scientific literacy is essential for students to understand and use scientific knowledge to make informed decisions, while critical thinking trains students to analyze information, evaluate arguments, and solve problems logically. Therefore, the intent of this study was to determine the effect of the guided inquiry learning model assisted by crossword puzzle media on students’ scientific literacy and critical thinking skills. The type of research used was quasi-experimental with a two-group pretest-posttest design. The sample consisted of two classes: class VII-8 as the control …


Importance Of S-Doped Porous Carbon Acidity And Visible Light Photoactivity For Its Antibacterial Activity, Danela Sadikaj, Abanob Fekri, Isabelle Bautista, Nafisatu Davis, Tasnim Agha Alkla, Muhammad Moueed Haider Mirza, Jiaying Wang, Phillip Stallworth, Natalie Hudson-Smith, Teresa J. Bandosz, Xiaojun Yu, Steven Greenbaum, Wanlu Li Nov 2025

Importance Of S-Doped Porous Carbon Acidity And Visible Light Photoactivity For Its Antibacterial Activity, Danela Sadikaj, Abanob Fekri, Isabelle Bautista, Nafisatu Davis, Tasnim Agha Alkla, Muhammad Moueed Haider Mirza, Jiaying Wang, Phillip Stallworth, Natalie Hudson-Smith, Teresa J. Bandosz, Xiaojun Yu, Steven Greenbaum, Wanlu Li

Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works

Bactericidal activity of sulfur-doped carbon has been investigated against a common Gram-negative bacterium, Escherichia coli K-12 (E. coli), in aqueous solution. Under dark conditions, 1 h contact of carbon with bacteria resulted in a 3–4 log decrease from the initial concentration of 7 log. When exposed to visible light, a 6–7 log decrease in E. coli was observed. The bactericidal activity under dark conditions was linked to the effects of functional groups, particularly sulfonic groups, which released protons that contributed to bacterial death. Even though under visible light no reactive oxygen species (ROS) were detected in electron paramagnetic …


Electrochemical Breath Sensors In Medical Diagnostics: Emerging Trends And Future Directions, Natalie E. Strom, Courtney J. Weber, Olja Simoska Nov 2025

Electrochemical Breath Sensors In Medical Diagnostics: Emerging Trends And Future Directions, Natalie E. Strom, Courtney J. Weber, Olja Simoska

Faculty Publications

With the rising prevalence of metabolic diseases, infections, and mental health disorders, there is a growing demand for noninvasive diagnostic tools that enable early detection and continuous health monitoring. In this context, exhaled breath biomarkers provide insight into physiological and pathological processes. Electrochemical breath sensors (EBSs) have emerged as a promising platform for rapid, real-time, and cost-effective disease tracking via the detection of volatile breath biomarkers, such as NH3, NO, and CO2. Recent advancements in electrode materials, biological recognition elements, and sensor architectures—spanning nanomaterials, enzymes, aptamers, and molecularly imprinted polymers—have enhanced the analytical performance of EBSs. …


Electrochemical Breath Sensors In Medical Diagnostics: Emerging Trends And Future Directions, Natalie E. Strom, Courtney J. Weber, Olja Simoska Nov 2025

Electrochemical Breath Sensors In Medical Diagnostics: Emerging Trends And Future Directions, Natalie E. Strom, Courtney J. Weber, Olja Simoska

Faculty Publications

With the rising prevalence of metabolic diseases, infections, and mental health disorders, there is a growing demand for noninvasive diagnostic tools that enable early detection and continuous health monitoring. In this context, exhaled breath biomarkers provide insight into physiological and pathological processes. Electrochemical breath sensors (EBSs) have emerged as a promising platform for rapid, real-time, and cost-effective disease tracking via the detection of volatile breath biomarkers, such as NH3, NO, and CO2. Recent advancements in electrode materials, biological recognition elements, and sensor architectures—spanning nanomaterials, enzymes, aptamers, and molecularly imprinted polymers—have enhanced the analytical performance of EBSs. …


Bioaccumulation Pattern Of Per- And Polyfluoroalkyl Substances (Pfas) In Fish Tissues From Two Freshwater Systems, Margaret D. Taiwo, Husam Kafeenah, David D. Duvernell, Michael O. Eze Nov 2025

Bioaccumulation Pattern Of Per- And Polyfluoroalkyl Substances (Pfas) In Fish Tissues From Two Freshwater Systems, Margaret D. Taiwo, Husam Kafeenah, David D. Duvernell, Michael O. Eze

Biological Sciences Faculty Research & Creative Works

Per- and polyfluoroalkyl substances (PFAS) are known for their persistence, ubiquity, bioaccumulation in different matrices of the environment and their detrimental effect on human health. In this study, we used EPA 1633 to examine the prevalence of ten PFAS compounds in two freshwater systems and investigated their bioaccumulation pattern across different tissues of grass carp fish (Ctenopharyngodon idella), common carp (Cyprinus carpio), and flathead catfish (Pylodictis olivaris). Among the PFAS compounds analyzed, PFBS exhibited the highest concentration in the freshwater sample, exceeding the U.S. EPA regulatory limit of 4 ng/L for drinking water. The total PFAS concentrations in the muscle, …


Versatile Nitration Of Bodipy Dyes Using No₂Bf₄: Effects Of Nitro Substituents On Spectroscopic And Self-Assembly Properties, Caroline Sarange Gwaro Oct 2025

Versatile Nitration Of Bodipy Dyes Using No₂Bf₄: Effects Of Nitro Substituents On Spectroscopic And Self-Assembly Properties, Caroline Sarange Gwaro

LSU Master's Theses

This study explores the regioselective nitration of BODIPY dyes at the 2, 3- and 2,6-positions using nitronium tetrafluoroborate (NO₂BF₄), offering a high-yielding and mild synthetic route. The introduction of nitro groups significantly alters the dyes’ photophysical and self-assembly properties. Mono-nitrated BODIPYs exhibit hypsochromic shifts in absorption and emission spectra, increased dipole moments, enhanced Stokes shifts, and reduced molar absorptivity. In contrast, di-nitrated analogs show bathochromic shifts and decreased dipole moments in both ground and excited states. Spectroscopic characterization was performed using UV-vis and fluorescence spectroscopy, supported by density functional theory (DFT) calculations. Self-assembly behavior was investigated in polar (acetonitrile) and …


Direct And Indirect Effects Of Water-Table Levels On Redox-Active Organic Matter Reduction In An Alaskan Rich Fen, J. E. Rush, E. S. Kane, Jason K. Keller, J. C. Bowen, Cassandra A. Zalman, E. S. Euskirchen, K. H. Wyatt, A. R. Rober, E. S. Hinckley Oct 2025

Direct And Indirect Effects Of Water-Table Levels On Redox-Active Organic Matter Reduction In An Alaskan Rich Fen, J. E. Rush, E. S. Kane, Jason K. Keller, J. C. Bowen, Cassandra A. Zalman, E. S. Euskirchen, K. H. Wyatt, A. R. Rober, E. S. Hinckley

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Redox-active organic matter (RAOM) reduction is an important control on methane production in northern peatlands, but it is unclear how global climate change will affect RAOM reduction. We investigated the effects of water-table levels on RAOM reduction by leveraging a long-term water-table manipulation experiment in an Alaskan fen, which includes Lowered and Raised treatment plots relative to a Control. Common substrate peat was incubated in each plot during one summer of experimental manipulation and another summer of site-wide flooding. During experimental manipulation, common substrate RAOM was more reduced in the Raised plot than the Lowered plot at both 10–20 cm …


Enzymes Of Calendula Officinalis L. As Affected By Foliar Application Of Nano-Nitrogen And Potassium Fertilizers, Under Water Stress Conditions, Aqeel Abdulabbas Alsudani, Qais Hussain Abbas Al-Semmak Oct 2025

Enzymes Of Calendula Officinalis L. As Affected By Foliar Application Of Nano-Nitrogen And Potassium Fertilizers, Under Water Stress Conditions, Aqeel Abdulabbas Alsudani, Qais Hussain Abbas Al-Semmak

Karbala International Journal of Modern Science

Water stress is a major environmental factor that limits the growth and productivity of Calendula officinalis L. To alleviate its negative effects, recent approaches have increasingly focused on nano-fertilizers that enhance plant antioxidant defenses. This study therefore aimed to evaluate the effect of foliar application of nano-nitrogen (0, 2, and 4 mL L⁻¹) and nano-potassium (0, 2, and 4 g L⁻¹) fertilizers under two irrigation regimes (100% and 50% of field capacity) on the activity of key antioxidant enzymes, including catalase (CAT), superoxide dismutase (SOD), and peroxidase (POD). The results revealed that irrigation at 50% field capacity significantly increased CAT, …


Development Trends And Priority Research Fields Of Electrochemical Discipline In The 15th Five Year Plan Period, Lin Zhuang, Wen-Bin Cai, Heng-Xing Ji, Qing Li, Gong-Wei Wang, Sen Xin, Qing Zhao, Fang-Yi Cheng, Yu-Guo Guo, Lan-Qun Mao, Yang Tian, Fei Wu, Li-Min Zhang, Yan Xiang, Jin-Song Hu, Rui Cao, Li Xiao, Hua-Bing Tao, Wei Xing, Dong-Ping Zhan, Hong-Gang Liao, Mei-Ling Xiao, Bin Ren, Zhang-Quan Peng, Rui Wen, Xiang Wang, Yue-Feng Song, Hou-Fu Lv, Bao-Yu Xia, Guo-Xiong Wang, Jun Cheng, Zhi-Pan Liu, Min Zhou, Bing Huang, Cun-Pu Li, Yu-Qin Zou, Shuang-Yin Wang, Hai-Bo Lin, Zi-Dong Wei Oct 2025

Development Trends And Priority Research Fields Of Electrochemical Discipline In The 15th Five Year Plan Period, Lin Zhuang, Wen-Bin Cai, Heng-Xing Ji, Qing Li, Gong-Wei Wang, Sen Xin, Qing Zhao, Fang-Yi Cheng, Yu-Guo Guo, Lan-Qun Mao, Yang Tian, Fei Wu, Li-Min Zhang, Yan Xiang, Jin-Song Hu, Rui Cao, Li Xiao, Hua-Bing Tao, Wei Xing, Dong-Ping Zhan, Hong-Gang Liao, Mei-Ling Xiao, Bin Ren, Zhang-Quan Peng, Rui Wen, Xiang Wang, Yue-Feng Song, Hou-Fu Lv, Bao-Yu Xia, Guo-Xiong Wang, Jun Cheng, Zhi-Pan Liu, Min Zhou, Bing Huang, Cun-Pu Li, Yu-Qin Zou, Shuang-Yin Wang, Hai-Bo Lin, Zi-Dong Wei

Journal of Electrochemistry

In fulfillment of the national science-and-technology development agenda, the Department of Chemical Sciences of the National Natural Science Foundation of China (NSFC) convened the Strategic Symposium on the Fifteenth Five-Year (2026–2030) Development Plan for Electrochemistry held in Xiamen on 29 August, 2025—the culminating year of the Fourteenth Five-Year (2021–2025) Development Plan. More than forty leading experts in the field of electrochemistry participated with spanning nine thematic fronts: Interfacial Electrocatalysis, Interfacial Electrochemistry for Energy Storage, Bioelectrochemistry, Electrochemistry of Hydrogen Energy, Electrochemical Micro-/Nano-Manufacturing, Operando Electrochemical Characterization, Electro-Thermal Coupling Catalysis, Theoretical and Computational Electrochemistry, and Electrochemical Synthesis. The forum assembled China’s foremost electrochemical …