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The Effect Of The Degree Of Cationic Charge On The Binding Strength Of A Cationic Starch-Kaolin Clay Coating, Hugh K. Myers

Masters Theses

No abstract provided.

The Kinetics Of The Metal Exchange Reaction Between Biseminodiacetatonickelate (Ii) And Copper (Ii), Stephen H. Erickson

Masters Theses

No abstract provided.

Kinetics Of The Metal Exchange Reaction Between N, N'-Bis (2-Picolyl) Ethylenediaminenickel (Ii) And Copper (Ii), Craig Lee Barsuhn

Masters Theses

No abstract provided.

Rate Of Initiation Of Pyrolysis Of Pentachloroethane Using The Toluene Carrier Gas Technique, Teodomiro Cuzcano

Masters Theses

No abstract provided.

The Synthesis And Reactions Of Some Α, Β-Unsaturated Diazoketones, Virendra K. Sood

Masters Theses

No abstract provided.

Rotationally Inelastic Molecular Scattering. Computational Tests Of Some Simple Solutions Of The Strong Coupling Problem, Thomas P. Tsien, Gregory A. Parker, Russell T. Pack

Faculty Publications

Partial cross sections (opacity functions) for rotational transitions in atom-diatom collisions are computed in the infinite-order sudden (IOS) approximation and compared with accurate close-coupling (CC) calculations. Agreement is good in the dominant coupling (small total angular momentum J) region. Simple methods for calculating integral inelastic cross sections are discussed, and it is found that accurate cross sections can often be computed very simply, even when large numbers of channels are coupled together, by using IOS or first-order sudden (FOS) approximations for small J and CC or exponential Born (EBDW) methods for large J.

Synthesis Of Some N2-Alkyl- And Dialkylsubstituted 2'-Deozyguanosines, Carl D. Carter

Chemistry and Chemical Biology ETDs

Various N²-alkyl- and dialkylsubstituted 2’-deoxyguanosines have been synthesized. After future conversion into nucleotides, these compounds are to be used for incorporation into DNA. The modified DNA is expected to be useful in complexing studies with actinomycin. The presence of the 2-amino group in a purine has earlier been shown to be required for binding of actinomycin. Possible reasons for this requirement are an electronic effect or a precise steric fit involving hydrogen bonding. By comparing the relative stability of the complex formed between actinomycin and modified DNA versus actinomycin and normal DNA a better understanding of the mechanism …

The Synthesis And Reactivity Of Pyrrolopyridazines, Phillip Dan Cook

Chemistry and Chemical Biology ETDs

A new general synthetic sequence and cyclization method was developed which utilizes parts of both the Reissert and Madelung indole cyclization methods and leads to substituted pyrrolo[2,3-d]pyridazines,pyrrolo[3,2-c]-pyridazines, and pyrrolo[2,3-c]pyridazines. Thus, ethyl pyridazinylpyruvatel-oxides substituted with an ethyl formimidate or acetimidate group adjacent to the pyruvate group provides immediate precursors to pyrrolopyridazines. Mild acid hydrolysis of the acylimidate and subsequent cyclodehydration. Parallel to the latter stage of the Reissert indole cyclization method, affords ethyl pyrrolopyridazine carboxylates in high yields. On the other hand, treatment of the acylimidates with base provided ethyl pyrrolopyridazine glyxalates in high yields in a manner similar to the …

Case Studies In Systems Chemistry, George Fleck

Open Educational Resources: Textbooks

This publication was produced as a teaching tool for college chemistry.The book is a text for a computer-based unit on the chemistry of acid-base titrations, and is designed for use with FORTRAN or BASIC.computer systems, and with a programmable electronic calculator, in a variety of educational settings. The text attempts to present computer programs that are relatively free of reliance on specialized large computer systems programs. The case-study approach presented is highly research and laboratory oriented. Similar subject matter is conventionally taught in most introductory college chemistry courses, but this text material attempts greater depth of instruction through utilization of …

The Role Of Mannosyl-Phosphoryl-Dihydropolyisoprenol In The Synthesis Of Mammalian Glycoproteins, John W. Baynes, An-Fei Hsu, Edward C. Heath

Faculty Publications

A mouse myeloma tumor was used as a model system to study the biochemical steps involved in the incorporation of mannose into glycoproteins. This tumor, MOPC-46B, synthesizes a K-type immunoglobulin light chain (K-46) which is a glycoprotein with a single oligosaccharide side chain containing mannose as one of its constituent sugars. MOPC-46B microsomal preparations contain enzymes which transfer mannose from the sugar nucleotide, GDPmannose, to endogenous lipid and protein acceptors. Formation of the mannolipid proceeds by the reversible transfer of mannose from GDP-mannose to an endogenous phospholipid. The mannolipid was purified and characterized by chemical methods and mass spectrometry as …

15th Annual Rocky Mountain Spectroscopy Conference

Rocky Mountain Conference on Magnetic Resonance

Program and abstracts from the 15th annual meeting of the Rocky Mountain Spectroscopy Conference, sponsored by the Rocky Mountain Section of the Society for Applied Spectroscopy. Held in Denver, Colorado, August 20-21, 1973.

Electron Transfer Rate Between Cobalt(Ii)-Cobalt(Iii) Polypyridyl Complexes In Nonaqueous Solvents, William Prow

Masters Theses & Specialist Projects

Numerous studies have been made in recent years on electron transfer reactions of transition metal complexes which proceed by either an inner- or an outer-sphere mechanism. However, except for the Fe(II)/ Fe(III) isotopic electron exchange system, few of the studies have been conducted in other than aqueous media. This study was undertaken to examine solvent effects on redox reactions of transition metal complexes which proceed by an outer-sphere mechanism.

During this study, the electron exchange rate between the bis(2,2',2"-tripyridyl)cobalt(II) complex and the tris(2,2'-dipyridyl) cobalt(III) complex was measured in a number of nonaqueous solvents. Rate measurements were made at three or …

Separation Of Copper (Ii) And Silver (I) By Differential Rates Of Extraction & Extraction Rate Studies Of Copper(Ii), Jon Hines

Masters Theses & Specialist Projects

It was the purpose of this work to study the extraction of Cu(II) and Ag(I) with dithizone in chloroform. This particular pair of elements was chosen for study for several reasons. The most prominent of these reasons is that these two elements are found together in nature and are often found combined in manufactured products. Being in the same periodic group, they exhibit similar chemical characteristics making them difficult to separate without special procedures. These similar chemical characteristics make the analysis of these elements difficult when in the presence of each other. Finally, it is of importance that both elements …

The Reactions Of Carbyl Sulfate With Weak Organic Bases, Cheryl Geiger

Masters Theses & Specialist Projects

The objective of this thesis is the study of the reactions of carbyl sulfate with two classes of weak bases: alcohols and nitriles. Of lesser maonitude the thesis will present a syncpsis of the probable mechanism of the reactions of carbyl sulfate.

The Intensity Of Ligand Absorption, Shing-Bong Chen

Masters Theses & Specialist Projects

The ultraviolet absorption spectra of a number of aryl phosphines and amines and transition metal complexes of triphenylphosphine have been determined. These data indicate that the intensity of the Õ* ¬ Õ phenyl ring transition is not only sensitive to the central atom attached to the ring but is also affected by the metal ion in the complex. Since the degree of covalency depends on the degree of back donation, the oxidation state of the metal ion was found to be the most important factor in determining the intensity of the absorption. The more covalent the metal-phosphine bond, the lower …

State Of Bacterial Dna After Uptake Into The Roots Of Germinating Barley Seeds, Larry Dale Lawson

Theses and Dissertations

Germinating barley seeds have been shown to take up Bacillus subtilis DNA labelled with 5-bromouracil and tritiated thymidine and retain the DNA in the root system without substantially degrading it. The percentage of bacterial DNA recovered from the total root DNA was independent of the amount of bacterial DNA available for uptake. Four observations indicated the stability of bacterial DNA after uptake into barley roots: (1) the bacterial DNA retained its transforming ability after recovery from the roots; (2) the labelled B. subtilis DNA showed similar CsCl density gradient patterns before uptake and after uptake; (3) most of the radioactivity …

Triplet-Triplet Energy Transfer In Indolylketones, Larry E. Hewitt

Dissertations

No abstract provided.

I. An Isothermal Titration Microcalorimeter. Ii. Importance Of Micronutrients In Nutrition. Iii. Zinc Bibliography, John Willard Gardner

Theses and Dissertations

I. An isothermal titration microcalorimeter having a colume of 4 ml and capable of temerature control to ±2 x 10-5°C is described. Major components include a constant temperature water bath controlled to ±3 x 10-4°C, a platinum reation vessel, and an isothermal control circuit consisting of constant Peltier thermoelectric cooling and variable Joule heating controlled by a thermistor in an AC Wheatstone bridge circuit. The calorimeter was tested by measuring the heat of ionization of water and was found to produce data accurate to ± 0.1% where small samples are used such as in the investigation of many biological systems.

Simultaneous Knudsen- And Torsion-Effusion Measurements Of The Vapor Pressures Of Tetraphenyl Silane And Hexaphenyl Disilane, Luz Marina Calle

Masters Theses

No abstract provided.

The Internal Chemical Shift. A Key To Bonding In Aromatic Molecules. I. Internal Shift Correlations, Donald W. Beistel, Holger E. Chen, P. J. Fryatt

Chemistry Faculty Research & Creative Works

The study of proton shift behavior in nine families of disubstituted benzenes has provided quantitative correlations of internal and meta shifts among all families. The equations of correlation are useful in the prediction of shifts to an error of 0.015 ppm. The studies demonstrate shift additivity for the 4-substituted halobenzenes and suggest a chain rule relationship for substituent effects in those compounds. For that reason, previous theories of substituent interactions involving inductive and resonance contributors appear incorrect when applied to proton shift data. In decreasing order of up field shift at the ortho protons the substituents studied include N(CH3)2, NH2, …

Synthesis And Selected Reactions Of [Pi]-(Arene) Chromium Tricarbonyls, Anthony L. Scaggs

Master's Theses

This project was concerned wit hthe preparation of two pi-(arene)-chromium tricarbonyl compounds that could serve as a synthetic intermediates to more complex systems. These intermediates would be particularly well-suited for the preparation of mono-complexed diaryl compounds. The two intermediates selected were pi-(acetophenone) chromium tricarbonyl and pi-(benzyl bromide) chromium tricarbonyl. After the intermediates had been synthesized, their utility in several selected reactions was to be examined.

Complexes Of The 2,2'-Bisacylhydrazide Of 3,3'-Bipyridine And The Dipicolinic Acid Dihydrazide Ligand Systems, William Leo Johnson Iii

Chemistry & Biochemistry Theses & Dissertations

The copper(II) complexes of the picolinic acid bydrazide (PH), the dipicolinic acid dibydrazide (DPH), and the 2,2'-bisacylbydrazide of 3,3'-bipyridine (DAR) ligand systems have been prepared and have been characterized by infrared spectroscopy. Coordination has been proposed to occur between the terminal amine, the amide nitrogen, and the ring nitrogen in each of the respective complexes.

Evidence for the loss of the amide hydrogen upon complexation of PH, DPH, and DAH with copper(II) has been observed by the n.m.r. study of the zinc(II) complexes of the PH and DAH ligand systems. This is in support of the structures proposed above for …

Aromatic Solvent Induced Shifts Of Trifluoromethyl Pyrazoles, Manuel Constantine Bourlas

Master's Theses

Nuclear Magnetic Resonance (NMR) has been used to study the keto-enol equilibrium in a number of trifluoro­methyl S-diketones as well as the dihydropyrazoles obtained when these S- diketones are reacted with thiosemicarbazide. The technique of Aromatic Solvent-Induced Shifts (ASIS) has been used to study the geometry of the collision complex and the strength of the association between solute and solvent. From the data presented, the stereochemistry of these pyrazoles has been determined and a reaction mechanism for their formation has been proposed.

The Growth And Toxicity Of The Florida Red Tide Organism, Gymnodinium Breve, Marion Tilton Doig Iii

USF Tampa Graduate Theses and Dissertations

Mass mortalities of marine organisms in the Gulf of Mexico have been associated with blooms of the unarmored dinoflagellate, Gymnodinium breve. This investigation concerns the factors affecting the growth of G. breve and the properties of a toxin produced by the organism.

A modification of the Flask Test of the Provisional Algal Assay Procedure of the Joint Industry/Government Task Force on Eutrophication was used to determine the response of G. breve to various natural waters and enrichments. The growth-promoting potential of natural waters obtained from areas where outbreaks of G. breve frequently occur was greater than that of waters …

Solution Diffusion Coefficients -- New And Improved Methods For Their Determination, Newton C. Fawcett

Chemistry and Chemical Biology ETDs

The previously existing method of determining diffusion coefficients (D values) by diffusion from capillaries is critically reviewed. A differential error analysis of the method is given, and a formula is derived for the upper error bound on D as a function of capillary length, time span of the experiment, and ratio of final to initial diffusant concentrations. It is concluded that when the initial concentration and capillary length are not corrected for convective loss of diffusant solution from the capillary, the errors in concentration and length are additive and can significantly affect the accuracy of D. A new method (the …

The Development Of A Defense System Against Coxsackievirus B5 Infection In Suckling Mice, Neal Shadoff

Senior Scholar Papers

There are many viruses that are able to infect the alimentary tract of man. Little is known, however, about the mechanism of infection itself or the pathophysiology of the gut during infection. 'The research reported here is concerned with the differences in susceptibility among suckling mice of various ages inoculated by the intraperitoneal and intragastric routes. Since the normal mode of entry of many viruses to the gut is via the oral route, Coxsackievirus B5, a human enterovirus which does attack this way, was utilized. It is a non-tumor producing RNA virus that has been shown to act similarly in …

Kinetic Properties Of Partially Purified Isocitrate Dehydrogenase, Devji Dedhia

Masters Theses & Specialist Projects

Within the past few years kinetic studies of NADP⁺- specific isocitrate dehydrogenase have been conducted extensively following isolation from bacteria, yeast and vertebrates. However, the kinetic properties of NADP⁺ - specific isocitrate dehydrogenase have not been adequately characterized in filamentous fungi. Therefore, the present study was undertaken to examine the kinetic behavior of partially purified NADP⁺ - specific isocitrate dehydrogenase enzyme isolated from Phycomyces blakesleeanus.

During this study Michaelis constants (Km) and maximum velocities (Vmax) were determined for threo-Ds-isocitrate, NADP⁺, and Mn²⁺ as well as the number of binding sites of these …

An Nmr Study Of Substituent Effects In Ortho-Substituted Aryl Methyl Sulfides, Luba Anne Pacala

Chemistry Honors Papers

This 51 page thesis involved the synthesis of a series of ortho substituted methyl phenyl sulfides and the subsequent interpretation of their nmr spectra to see if a linear correlation of reported ortho sigma constants with carbon 13-proton coupling constants or S-methyl chemical shifts existed. It was also the object of this study to determine a new set of ortho substituent constants based upon these data.

The Synthesis Of Imidazo [4, 5-C] Pyridazines And Pyridazino-As-Triazines, Dennis King Chesney

Chemistry and Chemical Biology ETDs

The preparation of the first examples of imidazo[4, 5-c]­pyridazine-2, 7-dithiones is described herein. Several of the S-methyl and S-benzyl derivatives have been prepared and the conditions required for the selective monoalkylation of the 2, 7-dithione have been determined. Several new derivatives of imidazo[4, 5-c]pyridazine and imidazo[4, 5-c]pyridazine-2 or 7-thione are also described. The preparation of several examples of the previously unknown heterocyclic ring systems, 1, 2-dihydropyridazino[4, 5-c]­-as-triazine and 3, 4-dihydropyridazino[4, 3-e]-as-triazine, is described. The preparation, isolation, and structure determination of the products from the reaction of methylamine with 3, 4, 5-tri­chloropyridazine are described. It was found that the reaction of …

New Techniques In Precision Gamma Scanning: Application To Fast Breeder Reactor Fuel Pins, John R. Phillips

Chemistry and Chemical Biology ETDs

A new precision gamma scanning system is described. The system is designed for the thorough, detailed, nondestructive characterization of irradiated fast reactor fuel pins. Gamma scanning data are given for failed fuel pin , transfer mechanisms of fission products, quantitative isotopic scan­ning, and differential burnup profiles.

The system consists of a scanning mechanism for the precise positioning (±0.001 in.) of the irradiated fuel pin, high density tungsten alloy collimators for defining the volume segment from which the gamma-ray spectra are collected, a large high resolution an anticoincidence detector assembly for resolving complex gamma-ray spectra, and a computer con­trolled data acquisition …