Digital Commons Network^™

Study On The Seasonal Endobacterial Profile Of Avicennia Officinalis, Focusing On Core Bacterial Consortia Within Mangrove Pneumatophores, Devi R R, Vinod Prabhakar

Karbala International Journal of Modern Science

Microhabitats are smaller pockets of ecosystems with unique conditions and they serve as major contributors of species richness. Mangrove plants offer a diverse array of such microhabitats (rhizosphere, phyllosphere, endosphereetc), and the inhabitant bacteria benefit the host by providing better salinity tolerance, faster and better nutrient mobilization, protection from phytopathogens and assistance in seed germination. Identification of such beneficial bacteria,their growth requirementsandmetabolism, willhave direct application in the field of agriculture and ecosystem restoration. Hence in this study, effort has been made to elucidate the seasonal numerical and compositional profile of pneumatophore bacterial consortia of Avicennia officinalis, from the mangrove …

Isolation And Characterization Of Lignin From Oil Palm Shells Using A Precipitation Method With Sulfuric Acid And Polyaluminum Chloride As Coagulant, Eny Kusrini, Ria Yolanda Arundina, Anwar Usman, Resti Marlina, Bambang Subiyanto, Volkan Degirmenci, Nofrijon Sofyan, Yudan Whulanza

AUIQ Complementary Biological System

Lignin has useful and significant properties such as stiffness, resistance to UV radiation, antioxidant, antimicrobial, high thermal stability, and high carbon content. Due to these properties, lignin can be used for several applications including wood adhesive, carbon-based material, and can be developed as a functional material composite. Isolation and utilization of lignin from lignocellulosic biomass offers significant opportunities in various now and future industrial applications mainly for development advanced materials. In this study, isolation and characterization of lignin from oil palm shells (OPS) was conducted. Lignin was isolated from OPS using the precipitation method with sulfuric acid and coagulation using …

Greenspace Variation And Its Effect On Telomere Length In The American Robin Dna, Valentina Rodriguez-Munoz, Elise Mittlestat, Mikus Abolins-Abols

The Cardinal Edge

Green spaces is a crucial component of our environment, and a contributor to relieving stress in human and wildlife health. Stress is one of the causing factors for a shorter lifespan in humans and other animals by directly accelerating the shortening length of the telomeres in our DNA. In this study we investigated to what extent urban vegetation explain telomere length in the American Robins Turdus migratorius living in the Louisville area. Specifically, we predicted that lower amount of vegetation will be associated with shorter telomeres. We caught the birds using mist nets, we collected blood samples, extracted DNA, and …

The Impact Of Air Pollution On The Cardiovascular System In American Robins: No2 Levels' And Ultrafine Particulate Levels' Correlation To The Ratio Of Immature To Mature Erythrocytes, Lauren A. Stine, Mikus Abolins-Abols

The Cardinal Edge

Abstract

Humans and animals, especially in an urban environment, are constantly ingesting air pollution. Since the industrial lifestyle is preferred or simply mandatory for many, the exact impacts of concentrated air pollution ingestion, especially on the cardiovascular system, needs to be unambiguous. It has already been seen that high levels of exposure to air pollution are correlated with increased rates of anemia in humans (Honda et al., 2017), (Morales-Ancajima et al., 2019), (Elbarbary et al., 2020), (Mehta et al., 2021). Further data indicates that air pollution ingestion may even directly cause some detrimental pro-inflammatory and oxidant-inducing effects on the cardiovascular …

Effects Of Sex, Cadmium, And High-Fat Diet On Accumulation Of Essential Metals In Mouse Kidneys., Justin Y. Xu, Adam Gaweda, Michelle Barati, Micheal Merchant, Jun Cai, Lu Cai, Madhavi J. Rane

The Cardinal Edge

Effects of cadmium and obesity on accumulation of essential metals in mouse kidney were evaluated. Starting in utero and continuing until 24 weeks postweaning, male/female mice were exposed to cadmium (0, 0.5, or 5 ppm) and were fed on Normal Diet (ND)/High-Fat Diet (HFD) post weaning. ICP-MS analysis was performed to evaluate cadmium and essential metals absorbed in the kidneys of aforementioned mice. Metals data obtained was analyzed using MANOVA with multiple comparisons (Bonferroni correction with p

Old Vs. New: An Experiment On The Efficacy Of Complexity-Focused Reproductive Biology Lectures For Undergraduate Biology Students, Ive N. Muse, Shraddha Patel, Linda Fuselier

The Cardinal Edge

Old vs. New: An Experiment on the Efficacy of Complexity-focused Reproductive Biology Lectures for Undergraduate Biology Students

Muse, Ive N.; Patel, Shraddha; Fuselier, Linda

Abstract

Undergraduate reproductive biology courses are traditionally taught in a reductive manner, prioritizing a binary understanding of sex which oversimplifies reproductive behaviors and reproductive system development across diverse taxa. Although this binary approach to lessons on reproduction is intended to benefit students in learning foundational human reproductive concepts, it does not teach the most recent research in reproductive biology, which identifies reproductive variation as the norm. The current study designed and implemented a lesson on reproductive …

North American Sucker Fish Diets In The Face Of Ecological Challenges (Catostomidae), Anesa Hozdic, Matthew Kolmann

The Cardinal Edge

Basic biological information, like fecundity, age at maturity, habitat occupation and range size, are critically important for conserving species under threat. However, funding for this sort of research is limited, especially for aquatic vertebrates like fishes, which have restricted ranges and are under threat from changes in land-use and watershed alteration. The suckers (Family Catostomidae) are freshwater fishes native to North America (and one species from China). Most species are presumed to be detritivorous, that is, feed on decaying plant and animal matter; however, the diet diversity of this family has never been analyzed at an evolutionary scale. Suckers are …

The Anti-Diabetic Drug Metformin Disrupts Feeding And Sleeping Behaviors In Drosophila Melanogaster, Lucas Fitzgerald

The Cardinal Edge

Dimethylbiguanide, also known as metformin, is the single most prescribed oral treatment for non-insulin dependent diabetes mellitus, or type 2 diabetes, in western countries. The primary mechanism of action that metformin acts through is the activation of AMP kinase, an important regulator of energy homeostasis. While the anti-diabetic effects of metformin are well documented, its effects on feeding and sleeping behaviors are not well characterized. Using the model organism Drosophila melanogaster, the mean daily quantity of food consumed was measured and compared between groups treated with several dosages of metformin. Feeding interactions such as meal frequency and length were …

Restoring History: Evaluating The Rehydration Potential Of Fish Specimens From A Forgotten Ichthyology Collection, Joseph Donohue, Matthew Kolmann, Emmy Delekta

The Cardinal Edge

Natural history collections are invaluable resources that document the record of Earth’s biodiversity. Such collections house physical specimens that can often be used in research and education (e.g., teaching tools for classes and public outreach events). The William Clay Ichthyology Collection at the University of Louisville contains thousands of fish specimens collected over the past century from locations in and around Kentucky, North America, Central and South America, and even Lake Malawi in Africa. Despite the incredible assortment of specimens present, this collection fell into disarray as departmental interests shifted over the last twenty-five years. This led to the desiccation …

How Medical Students Address Mental Health During Standardized Patient Interactions, Bhoomi S. Shah, Laura Weingartner, Emily J. Noonan

The Cardinal Edge

How Medical Students Address Mental Health during Standardized Patient Interactions

Bhoomi Shah B.S. Candidate; Emily J Noonan, PhD, MA; Laura A. Weingartner, PhD, MS

BACKGROUND:

As mental health needs are increasingly recognized around the world, it has become an increasingly important topic within medical education to ensure that medical professionals are well-prepared to address these concerns and provide adequate mental health care to patients. Our research examines the language that medical students used to assess and address mental health concerns during clinical skills training.

METHODS:

We observed standardized patient interactions with 85 medical students from the University of Louisville School …

The Effect Of Prenatal Vape Exposure On Liver Gene Expression In Weanling Mice, Mindy Yin, Selma Podbicanin, Bella Fieger, Nina Pauig, Katelyn Chism, Lucas Georges, Isaiah Burciaga, Cynthia Corbitt, Rachel Neal

The Cardinal Edge

The use of E-cigarettes is a fairly recent phenomenon. Vaping is thought of as the “healthier” alternative to smoking cigarettes, yet we know little about the developmental toxicity of commercially available vaping products. The Barker Hypothesis (or the Developmental Basis of Adult Disease Hypothesis) proposes that developmental nutrient restriction or toxicant exposure increases the risk of diseases later in life such as cardiovascular disease, fatty liver, and metabolic diseases. In this study, adult female C57Bl/6 mice were exposed to Vuse™ Alto Golden Tobacco pods (5% nicotine) 4 days before mating and throughout gestation (GD19) for 1 hour/day each day. Offspring …

The Role Of Adhd As A Risk Factor In Alzheimer's Disease, Evelyn Fulmer

The Cardinal Edge

In recent years, the prevalence of attention-deficit/hyperactivity disorder (ADHD) and Alzheimer’s disease (AD) has increased significantly. While these disorders initially seem unrelated, ADHD and AD pose similarities that indicate a more involved relationship between them. To understand this relationship, this review delves into the current research proposing ADHD as a potential risk factor in the development of Alzheimer's disease, examining genetic predispositions, shared risk factors, and affected mechanistic pathways that influence the aging process.

A Hopeful Overview On Aging, Rafael Demarco

The Cardinal Edge

N/A

Sdf-1Α Mediates Primary Tumor Escape In Glioblastoma Through Activation Of Mesenchymal Transitions, Charles T. Froman-Glover

The Cardinal Edge

Glioblastoma (GBM), a highly aggressive primary brain tumor originating in glial cells, poses a significant challenge due to its rapid growth and invasive nature within healthy brain tissue.

Current treatments involve surgical resection, chemotherapy, and radiation. These treatments alone are not enough to cure this disease, and a better understanding of the mechanics of the tumor's micro-environment is imperative to furthering the field of cancer research. This research focuses on understanding the tumor microenvironment's impact, specifically investigating the role of stromal cell-derived factor 1 (SDF-1) mechanics on GBM aggressiveness. SDF-1 is known to facilitate disease progression by facilitating chemotaxis toward …

Largemouth Bass Neurocranium, Owen Duerbeck, Ian Thelwell, Oliva Weeks

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Black Grouper Neurocranium, Angelina Trapani-Banyra, Victoria Bruno, Mason Schleicher

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Tissue Proteomics Of Feline Mammary Carcinoma: Identification Of Potential Biomarkers Based On Metastatic Status And Histopathological Characteristics, Weejarin Paphussaro, Sittiruk Roytrakul, Narumon Phaonakrop, Sawanya Charoenlappanit, Anudep Rungsipipat, Theerawat Tharasanit, Gunnaporn Suriyaphol Assoc. Prof.

The Thai Journal of Veterinary Medicine

Feline mammary carcinoma (FMC) is a prevalent and aggressive cancer with high metastatic potential. Few tissue biomarkers have been reported to help evaluate disease progression in FMC. This study aimed to analyze the tissue proteomic profiles of metastatic feline mammary carcinoma (mFMC) and non-metastatic FMC (NmFMC) across various histological grades (HGs) and histological types (HTs) using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Tissue samples were collected from 13 NmFMC, 26 mFMC and 13 healthy controls (CTRL). Samples were trypsinized and subjected to LC-MS/MS. Proteome results were analyzed based on the metastatic status, HGs and HTs of the samples. The findings revealed …

Dog Sniffing Biomechanic Responses In An Odor Detection Test Of Odorants With Differing Physical Properties, Lydia Burnett, Nicholas Hebdon, Pete A. Stevens, Monica Moljo, Lindsay D. Waldrop, Lauryn Degreeff

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Dogs are utilized in forensic science for their extensive scent detection capabilities. They are often considered the “gold standard” in field detection for targets such as illicit drugs and explosives. Despite their prevalence in the field, relatively little is known about how dogs interact with and transport volatile organic compounds through their olfactory system. In this study, two groups of dogs were utilized – Sport detection dogs (n=19) that participate in the National Association of Canine Scent Work and have achieved advanced standing through training and successful search competitions and law enforcement explosive detection dogs (n=8) which were included for …

Phagolysosomes Break Down The Membrane Of A Non-Apoptotic Corpse Independent Of Macroautophagy, Shruti Kolli, Cassidy J. Kline, Kimya M. Rad, Ann M. Wehman

Biological Sciences: Faculty Scholarship

Cell corpses must be cleared in an efficient manner to maintain tissue homeostasis and regulate immune responses. Ubiquitin-like Atg8/LC3 family proteins promote the degradation of membranes and internal cargo during both macroautophagy and corpse clearance, raising the question how macroautophagy contributes to corpse clearance. Studying the clearance of non-apoptotic dying polar bodies in Caenorhabditis elegans embryos, we show that the LC3 ortholog LGG-2 is enriched inside the polar body phagolysosome independent of autophagosome formation. We demonstrate that ATG-16.1 and ATG-16.2, which promote membrane association of lipidated Atg8/LC3 proteins, redundantly promote polar body membrane breakdown in phagolysosomes independent of their role …

Exploring Pcat3 Expression In Arthritis: Proinflammatory Marker Patterns And P53 Involvement, Aida H. Alobaidi, Entkhab M. A. Alanisi, Khalid A. Alyodawi

AUIQ Complementary Biological System

This study investigated the role of long non-coding RNA (lncRNA) PCAT3 in arthritis, focusing on its impact on proinflammatory markers. Researchers analyzed both mRNA and protein levels of various proinflammatory markers (TNF-α, IL-1β, IL-4, IL-6, IL-8, IL-10, and IL-13) in arthritis patients and compared them to healthy controls. Additionally, PCAT3 expression was assessed in both patient groups and further investigated using siRNA knockdown in the human synovial cell line SW982. Results revealed distinct expression patterns of proinflammatory markers in arthritis patients, with TNF-α and IL-6 showing the highest levels. PCAT3 expression was significantly elevated in arthritis patients compared to controls. …

Snakehead Neurocranium, Alexis K. Crass, Megan E. Martiello, Matthew D. Gassmann, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Place, Space, And Shifting Views Of Nature, Rachel Tracey

Runkle Woods Symposia

In her reflective presentation, Rachel Tracy explores her evolving relationship with nature and wilderness. Initially disinterested and uncomfortable in natural settings, she describes how her perspective shifted through class discussions, personal reflection, and immersive experiences in the outdoors. Concepts such as “space versus place” helped her understand the emotional and historical significance of natural environments. Through this journey, she discovered joy in simply being present in nature, ultimately gaining a deeper appreciation for the natural world and its ability to exist and thrive without human involvement.

Culture, Nature, And Reflection: The Settler’S Impact On Life Today, Erin Thomas

Runkle Woods Symposia

Erin Thomas, a senior English major at Wright State University, reflects on the intersection of wilderness, identity, and cultural erasure. Drawing from her Indigenous heritage and experiences in the course Woods and Wilderness, she critiques the romanticized, Eurocentric view of nature as untouched and separate from humanity. Instead, Thomas highlights how wilderness has been shaped by settler colonialism and exclusionary narratives that often ignore Indigenous presence and histories. Her presentation calls for a more inclusive and honest understanding of wilderness—one that honors marginalized voices and acknowledges the land’s complex cultural past.

Wilderness Myth And Reality: Human Views And Uses Of Nature, Evan Hardern

Runkle Woods Symposia

In his essay and presentation, Wright State English major Evan Harder critically examines modern conceptions of wilderness and challenges the Romantic ideal that moral purity and personal virtue are inherently tied to time spent in nature. Drawing on writers such as Wordsworth, Emerson, and Thoreau, Harder interrogates the cultural myth of wilderness as a pristine, untouched realm separate from civilization. He argues that our understanding of nature is a constructed concept—born from the development of cities and agriculture—and often overlooks the long histories of human habitation in places now designated as “natural” or “wild.” Through examples like Cuyahoga Valley National …

The Concept Of Wilderness In Western Culture And Its Sacredness, Shannon Doyal

Runkle Woods Symposia

Shannon Doyal, a Professional Writing student at Wright State, explores how wilderness has been perceived throughout American history—as both a physical space and a powerful spiritual symbol. Drawing from Indigenous perspectives, early settler narratives, Transcendentalist writings, and American literature, she traces the evolving cultural and emotional significance of wilderness. From a place of fear and survival to one of introspection and sacred connection, wilderness reflects our changing relationship with nature and ourselves. As someone whose spirituality honors the cycles of nature, Doyal argues that reclaiming wilderness as a sacred and emotional space is vital—not only for environmental preservation but also …

Endangered Bats In The Runkle Woods, Volker Bahn

Runkle Woods Symposia

Since 2019, Dr. Volker Bahn’s lab has been monitoring bat populations in the Runkle Woods and nearby sites, using acoustic detectors to track species presence and activity over time. With bats representing about 20% of all mammal species globally, their ecological role—particularly in insect control—is vital. The presentation highlights the diversity of local bat species, with 10 of Ohio's 11 expected species documented, ranging from the abundant big brown and red bats to the federally endangered Indiana and northern long-eared bats. Dr. Bahn discusses patterns in bat activity across years, potential drivers such as precipitation, and the concerning declines in …

Water Quality Management In The Runkle Woods, Krystal Demarco, Donavon Mishler-Laporte, Cassie Dunn, Parneet Dhillon, Reagan Hardyman

Runkle Woods Symposia

This project addresses the growing issue of salt pollution in Wright State Woods, with a specific focus on sodium chloride runoff from deicing agents. Elevated salt levels, stemming from university parking lots and surrounding infrastructure, have been linked to soil degradation, vegetation stress, and aquatic habitat damage. By analyzing salt flow patterns and assessing ecological impacts, including EPA-reported chloride violations, the team identified critical areas of concern such as Outfall #2. Proposed mitigation strategies include the use of salt-tolerant tree species, alternative deicers (e.g., acetate- or carbohydrate-based), physical barriers, and expanded retention ponds and filter dams.

Invertebrates As Indicators Of Water Quality In The Runkle Woods, Dillynn Blevins, Bhavishya Ratnavelu, Lauren Stetz, Corey Walls

Runkle Woods Symposia

This project investigates water quality and aquatic invertebrate habitat health in the Wright State Woods, aiming to assess current conditions and implement targeted conservation strategies. Using indicators such as dissolved oxygen, nutrient concentrations, and the presence of sensitive macroinvertebrates (e.g., mayflies, stoneflies, caddisflies), the team evaluates stream health. Data collection follows established protocols, including EPT indexing and seasonal surveys. Conservation recommendations include stream aeration maintenance, removal of non-native vegetation, soil inoculation, and the construction of rain gardens and green roofs to reduce runoff.

An Accessible Trail For The Runkle Woods, Sarah Bingham, Terri Dozier, Logan Huber, Nicole Owino, Nathan Shafer

Runkle Woods Symposia

This presentation outlines a student-led initiative to enhance a pre-existing trail in the Runkle Woods with educational conservation projects and signage. The project aims to increase accessibility and student engagement with Wright State’s natural areas. Three key conservation efforts are highlighted along the trail: prairie restoration to support native biodiversity and pollinators, erosion and runoff mitigation using native vegetation and riff-raff, and bat conservation through habitat preservation and installation of artificial roosts. The project emphasizes experiential learning, sustainability, and community involvement in environmental stewardship.

Management Of The Invasive Honeysuckle (Lonicera Maackii), Mesa Grine, Daniel Hazelett, Cassie Healy, Padma Deepika Kandregula

Runkle Woods Symposia

This presentation addresses the ecological threat posed by invasive honeysuckle in the Runkle Woods on Wright State's campus. Originally from Europe and Asia, honeysuckle aggressively outcompetes native flora due to its rapid growth, shade tolerance, and allelopathic properties. The students observed widespread honeysuckle in both new and old growth forest areas, with greater density in younger regions. Ineffective control methods—such as cutting without herbicide—often worsen infestations. Drawing on a regional study, the students propose a targeted management plan involving cutting and herbicide application, stem injection for larger plants, and reintroducing native species like spicebush. Their strategy aims to reduce honeysuckle …