Digital Commons Network^™

Acquisition Behavior Response: Investigating The Ability Of Leptoglossus Phyllopus To Choose Between A “Good” Versus “Sub-Optimal” Strain Of Caballeronia, Irene L. Pham

2026 Spring Honors Capstones Projects

Leptoglossus phyllopus is a polyphagous pest that primarily feasts on citrus, tomatoes, and legumes. They must form a mutualistic symbiosis with Caballeronia every generation by ingesting the bacterium from their environment. However, not all species of Caballeronia confer the same fitness on the L. phyllopus host, raising the question of whether L. phyllopus possesses a partner choice mechanism that would allow it to distinguish between a good (GAOX1) and a suboptimal (Lep1P3) symbiosis partner. This was examined by conducting a choice experiment in which the two symbionts (GAOX1 vs. Lep1P3) were placed in a plastic box, and the bug’s roaming …

Attentional Mechanisms Of Language In Infants With Down Syndrome, Fragile X Syndrome And Siblings Of Children With Autism, Isabelle Robinson

Caravel Undergraduate Research Journal

Children with Down syndrome (DS), fragile X syndrome (FXS), or younger siblings of a child with autism spectrum disorder (ASIB) often exhibit atypical object exploration and social engagement, which can affect important learning opportunities. The purpose of this study was to examine group differences in social attention shifting and attentional disengagement between infants with DS, FXS, and ASIBs. This study utilized data from a longitudinal study collected from 12-month-old infants with DS (n = 13), FXS (n = 14), and ASIBs (n = 24). No group differences were seen for social attention shifting. However, infants with DS …

Examining Biobehavioral Indicators Of Adhd In Children With Fxs, Hannah Pressler, Kayla Smith, Ramsey Coyle, Elizabeth Will, Jane E. Roberts

Caravel Undergraduate Research Journal

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention and hyperactivity/impulsivity behaviors that are inconsistent with developmental age. Children with fragile X syndrome (FXS), a genetic neurodevelopmental disorder, are often diagnosed with comorbid ADHD (53–59% of males with FXS). Despite the prevalence of ADHD in FXS, little is known about the early manifestation of ADHD. The current project aims to explore group differences in play behaviors between children with FXS and typically developing (TD) children as well as the relationship between infant play behavior and heart activity to future ADHD attention outcomes. Participants included male children with FXS and …

Early Behavioral And Physiological Predictors Of Autism In 12-Month-Old Siblings Of Children With Autism, Nicolas Poupore, Kayla Smith, Abigail L. Hogan, Jane E. Roberts Ph.D.

Caravel Undergraduate Research Journal

Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by social-communicative deficits and repetitive behaviors. Complementing behavioral (i.e., The Autism Observation Scale for Infants (AOSI) scores) and physiological markers (i.e., respiratory sinus arrhythmia (RSA), heart rate (HR)) may improve early identification of ASD and provide insights into the neurobiological mechanisms contributing to early ASD symptoms. Younger siblings of a child with ASD (ASIBs) had significantly higher AOSI Total Scores and AOSI Marker Scores in comparison to Low Risk Controls (LRCs). RSA significantly decreased from a Baseline to AOSI for both groups, but only for the ASIB group was a negative …

The Cranial Morphology Of Large Wild Versus Captive Felids, Bryttin Boyde, Hannah Selvey

Caravel Undergraduate Research Journal

Studies have shown that carnivores in captivity that are fed soft diets have more periodontal problems and that the morphology of their skeletons, skulls specifically, responds to environmental and behavior factors. Considering that captive diet affects teeth and gums, we have conducted research on Dr. Adam Hartstone-Rose’s hypothesis that variation will also be discernible through the examination of cranial morphology. We compared captive and wild lions Panthera leo and tigers Panthera tigris to see if differences were present, then analyzed data collected by a microscribe using a 3D morphometric analysis program. Next, Principal Component Analysis was completed to account for …

A Review Of Video Game Effects And Uses, David Corso

Caravel Undergraduate Research Journal

Video games are versatile in their form and function. Whether they’re training doctors or offsetting Alzheimer’s disease, video games can exercise both mental and physical features, train specific skills for a number of jobs, educate players about events and phenomenon in our world, research and understand natural human processes, and they can be designed for a number of other purposes. Multiple studies have demonstrated the effects of video games on physiological and cognitive levels—positive, negative, and everything in between. This paper identifies various physical and psychological effects that video games produce, and it suggests ways in which video games can …

Learning About Learning: Cognitive Gaming As A Technology Of The Self, David Corso

Caravel Undergraduate Research Journal

Humans perceive and interpret video games in various ways. When viewed as a cognitive process, video games facilitate intellectual growth and development. This piece analyzes selected works by French intellectual Michel Foucault and educational game design researcher Kurt Squire to explain how video game play elicits various cognitive and metacognitive processes. The video discusses how gameplay contributes to the development of cognitive skills, such as memory and attention. It explains how gameplay facilitates learning about learning as well as how video games provide transferable knowledge. An interpretation of Foucault’s “technology of the self” indicates how individuals might use gameplay to …

Exploring Microbiome Communities Of Two Belize Coral Species Five Years After Reciprocal Transplant, Lily E. Kratz

Biology Honors Papers

Coral holobionts, which include the coral animal host, dinoflagellate algae, bacteria, etc., support coral reef biodiversity by providing habitat to many marine species. In the face of global change, identifying and understanding the microbial diversity of corals is extremely important because their survival indicates overall ocean health. Coral-associated bacterial and algal communities contribute to the health and survival of a coral species through creating resistance to stressors and supplying essential nutrients. As coral reef environments continue to change, microbial communities must respond to ensure the survival of reef-building corals. To investigate if coral microbiomes possess the ability to acclimatize to …

Bats In A Modified Suburban Landscape, Brittany Morgera

Biology Honors Papers

This research assesses bat species richness and activity across a gradient of suburban habitat modification surrounding Ursinus College and Green Lane Park in Montgomery County, located in southeastern Pennsylvania. Habitat modification was quantified using GIS-based land-cover metrics (e.g. impervious surfaces and canopy cover), and bat activity and species richness were measured though acoustic surveys conducted at 15 sites during the summers of 2024 and 2025. The project tests the hypothesis that increasing habitat modification has a negative correlation with bat species richness and activity.

Stemflows And Preferential Flows: A Historical Review And Challenges For The Future, Keith Beven, John T. Van Stan Ii

Biological, Geological, and Environmental Faculty Publications

This paper provides a historically-grounded review and research agenda on a generally neglected issue in hillslope hydrology and hydrological modelling: the role of stemflow in initiating preferential flow in soils. While stemflow typically represents a small fraction of incident rainfall, it can concentrate water fluxes by up to similar to 20-fold at tree bases, creating localised infiltration intensities that exceed those from throughfall. Some new historical context for throughfall and stemflow studies from the 19th Century is presented, including a summary of stemflow research in a wide range of vegetation types and environments. The evidence for preferential flows resulting from …

Red Lines, Green Blooms: Assessing The Effects Of Historical Environmental Disparity On Algal Communities In The Twin Cities, Mn, Georgia C. Akins

Environmental Studies Honors Projects

Redlining, a discriminatory housing policy from the 1930s, shaped lastng urban inequalites that may extend to environmental conditons. This study examines links between redlining and urban water quality in the Twin Cites using algal communites as indicators. Across 28 water bodies sampled in 2022 and 2024, physical, chemical, and biological metrics were compared by redlining grade. Results show limited relatonships between redlining and most variables, with only surface water temperature differing significantly. Nutrients and algal diversity were unrelated to redlining, instead reflectng present-day conditons. These findings suggest contemporary factors play a stronger role than redlining in shaping urban freshwater ecosystems.

Employing Zebrafish To Understand Genetic Drivers Of Epilepsy-Related Comorbid Behaviors, Chinwendu Ononuju, Kharma Hall, Olivia Beatty, Scott C. Baraban, Colleen Carpenter-Swanson

Biology Faculty Publications

Children with epilepsy frequently experience a range of significant comorbidities beyond seizures, such as motor dysfunction, cognitive impairment, and neurodevelopmental delays. In some cases, these comorbidities contribute more significantly to overall disease burden than the seizures themselves. To improve quality-of-life (QOL) for these children, treatment options should be selected that control seizures and ameliorate comorbidities. Unfortunately, such therapeutics remain largely elusive. Addressing this issue requires suitable preclinical models. Here we used CRISPR-generated zebrafish with single-gene mutations linked to pediatric epilepsy and applied clinically-relevant behavioral assays to study the effects of these mutations. Using high-throughput locomotion-based assays, we uncovered errors in …

The Impacts Of High Protein Diet On Sleep And Mood In Women With Polycystic Ovary Syndrome (Pcos), Lily G. Hiegel

Biological Sciences Undergraduate Honors Theses

The objective of this study is to determine whether adherence to a high protein diet over a sixteen-week period leads to improvements in sleep quality and mood in women with PCOS. It is hypothesized that individuals following the high protein diet will demonstrate significantly better sleep quality and more favorable mood profiles compared to individuals not following the high protein diet. By targeting insulin resistance and dietary carbohydrate intake, this intervention may influence multiple pathways involved in PCOS symptomatology, including hormonal regulation, metabolic function, sleep physiology, and psychological wellbeing.

Long-Term Stimulant Use Is Associated With Normalized White Matter Integrity In The Vta-Nacc Pathway In Adolescents, Isaac T. Arsenault

Biological Sciences Undergraduate Honors Theses

Medical practitioners are diagnosing Attention-Deficit/Hyperactivity Disorder (ADHD) at a high and ever-increasing rate. The use of stimulant medication to treat ADHD is also increasing and is associated with changes in the brain. Past research found that children with ADHD have lower volume in reward neurocircuitry, such as the ventral tegmental area (VTA) and the nucleus accumbens (NAcc). Research has also found that stimulant usage in those with ADHD might “normalize” the reward circuits. However, few longitudinal studies have directly tested the long-term effects of stimulant medication on brain development. Here we tested whether long-term stimulant use is associated with changes …

Status Of The Potentially Invasive Australian Redclaw Crayfish (Cherax Quadricarinatus), Margaret (Addie) Munn

Biology Theses

The introduction of invasive species, including crayfish, is common through aquaculture and aquarium trade pathways and is an important factor causing the decline and/or extinction of native species. Invasive species cause billions of dollars in damages annually and threaten almost half of the native species in the United States. Australian Redclaw Crayfish (Redclaws) are a species of large individuals that originated in Australia and New Guinea and have been introduced specifically for aquaculture and the aquarium trade. Redclaws are known to thrive in tropical and subtropical locations. They can tolerate high temperatures and low oxygen and are generalist omnivores that …

Structure Of The Spoiie Protein In Clostridioides Difficile, Robert B. Bauer

Biological Sciences Undergraduate Honors Theses

Clostridioides difficile is an opportunistic pathogen responsible for severe gastrointestinal infection. C. difficile-related infection is extremely prevalent in healthcare facilities, causing roughly 30,000 deaths annually in the United States alone. Its main mechanism of virulence is sporulation, which is directed by the SpoIIE protein. This makes SpoIIE an attractive target for the remedy and prevention of infections. The objective of this study was to analyze its structure using both lab techniques and artificial intelligence modeling. A truncated version of this protein, SpoII∆TM, was expressed and analyzed using optimal conditions previously determined in the lab. SDS-PAGE results and analyses confirmed …

From Chaos To Clockwork: Investigating The Role Of Circadian Genes In Metabolic Development Of 2nd And 3rd Instar Drosophila Larvae, Elliott R. Ruegsegger, Stephanie Hood, Amy Poe

Biological Sciences Undergraduate Honors Theses

Circadian clocks regulate daily physiological and metabolic rhythms across many organisms. In Drosophila melanogaster, the molecular clock involving period (per) and timeless regulates gene expression across 24-hour cycles. Circadian rhythms are well characterized in adult, mature organisms, but their emergence during early developmental stages remain poorly understood. In D. melanogaster, the circadian regulation of sleep and feeding rhythms emerges during the 3rd instar larval stage. This suggests that the circadian regulation of metabolism may also arise during this stage. Further, the metabolic consequences of circadian clock disruptions during this developmentally rich period remain unclear. This research aimed to …

Decomposition In Urban Forest Patches Across A New York-New Jersey Urbanization Gradient, Cailee Sprouse

Theses, Dissertations and Culminating Projects

"Urbanization causes habitat fragmentation, pollution, homogenization of soil profiles, and replacement of native flora and fauna, which can alter vital ecological processes like decomposition. It is essential to investigate the impacts urbanization may have on ecosystem functioning to better inform urban land management. Studies have shown conflicting results on the impacts of urbanization on soil decomposition rates, with some showing higher, lower, or similar decomposition rates in urban soils compared to rural soils. This study aims to investigate the effects of urbanization and soil characteristics on decomposition rates in three urban forest patches in New Jersey and New York using …

How Does Five Days Of Tapering Effect Rates Of Fatigue And Recovery In Collegiate Male Swimmers?, Riley Yerks

Celebrating Scholarship and Creativity Day (2018-)

This study was conducted on the members of the 2025-26 St. John's "Johnnies" swim and dive team. This study used both subjective surveys and objective HRV readings that the swimmers took before and after practice. The first day of testing occurred on the last day of the regular training season, and the second day of testing occurred on the last day of tapered training. Results of the surveys and HRV readings were compared between pre and post-practice, and pre and post-taper. The subjective surveys showed how the swimmers themselves felt in terms of physical and mental energy and fatigue, and …

Ai×Life 2026: Advances In Computational Biology Across Scales For Life & Health Sciences, Suma Mohan S., Devika N. T., Pranavathiyani G.

Conference Proceedings

Book of Abstracts of the International Conference, AIxLife 2026: Advances in Computational Biology Across Scales for Life & Health Sciences, held on 17–18 April 2026, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, INDIA 

About the Conference

Conventional computational biology laid the foundation for biological data analysis through statistical models, algorithms, and curated databases, enabling insights into genes, proteins, and pathways. Today, the integration of artificial intelligence, spanning machine learning, deep learning, and large language models (LLMs) is driving a transformative shift across biological scales, from atomic and molecular interactions to pathways, cellular systems, organisms, and populations.

AI-powered approaches …

Group B Streptococcus In Pregnant Women: Universal Guidelines And Protocols, Dania Presteguin

Undergraduate Honors Thesis Collection

Background: Group B Streptococcus (GBS) is a leading cause of maternal sepsis and neonatal mortality globally. Variability in screening and treatment guidelines influences global disease burden.

Objective: This study uses a cross-national analysis to compare screening and treatment guidelines and their impact on prevalence, screening, intrapartum antibiotic prophylaxis (IAP), and maternal-neonatal clinical manifestations Methodology: A systematic review of secondary literature was conducted using PubMed, Scopus, and CINAHL (2010-2025). Inclusion criteria include maternal GBS colonization and one or more measures of interventions and neonatal infection rates. No geographic or demographic restrictions were applied. A total of 67 studies were screened, and …

Assessing The Conservation Needs Of Native Texas Crayfish Species Through Distribution Analysis And Species Distribution Modeling, Elizabeth J. Croft

Biology Theses

Crayfish have essential roles in ecosystems because they are ecosystem engineers and keystone species. However, crayfish species are threatened by degradation and loss of habitats, introduction of invasive species, and high levels of endemism. Texas provides no legal protections for crayfish, despite its large number of species and endemics in the state. The overall goal of this study is to clarify the distributions of native Texas crayfish species using literature records, citizens science, and field sampling data, and highlight species in need of more conservation research. Occurrence records from all collected data were combined to visualize the distributions of species …

A Series Of Investigations On The L. Cornutus Host System And Bivesiculid Sp. Cercariae, Briana K. Zaffiro

All HCAS Student Capstones, Theses, and Dissertations

Rising global temperatures are likely modulating parasite-host interactions, yet the direction and magnitude of these changes remain uncertain. Rarely are these interactions viewed from both a host and parasite perspective. Using both CT_max, or Critical Thermal Maximum, and Clark-type polarographic oxygen microelectrodes, the physiological metabolic effects are investigated. CT_max is examined in Common Shiners, Luxilis cornutus, and is shown to be modulated by parasitism: uninfected fish had the highest CT_max average of 37.0°C, whereas heavily infected fish had decreased CT_max averaging 35°C. Prior to the parasite metabolic investigation, a suitable medium was determined, as …

Shape Variation In The Mandible Of The Borophagine Canids And Implications For Predatory Behavior, Benjamin Neavear

Theses, Dissertations and Culminating Projects

The borophagines are an extinct lineage of canids that inhabited North America for more than 20 million years. This group included genera such as Aelurodon, Borophagus, and Epicyon. Borophagines are commonly referred to as “bone-crushing dogs” because their skull morphology converged with that of extant hyenas, predators capable of consuming bone. The purpose of this study was to determine whether convergence was present in the mandible, an anatomical structure strongly correlated with feeding behavior, particularly in the genera Aelurodon and Borophagus. It was hypothesized that most borophagine taxa possessed mandibular shapes similar to those of hyenas. Numerous mandibular characters were …

Structural Evidence For Innervation Of A Single Epitheliomuscular Cell By Multiple Sensory Neurons In The Sea Anemone Nematostella Vectensis, Aparajita Das

Graduate Theses and Dissertations

Abstract Here, I report new ultrastructural evidence for multineuronal innervation (many-one) of a single epithelia-muscular cell in sea-anemone cnidarian Nematostella vectensis. Using Serial Block-Face Scanning Electron Microscopy (SBF-SEM) and ImageJ, I found that EMCs are located at the base of ectoderm, with an elongated cell body that includes basal processes, a bilobed nucleus, and myofibrils aligned parallel to the basal surface along with their structural quantification. Notably, I found multiple mechanosensory neurons form synapses with a single EMC. These findings enhance our understanding of cnidarian neuromuscular organization and reveal that coordination between sensory and contractile systems in N. vectensis is …

Identifying The Role Of Human Dna Polymerase Delta During Human Cytomegalovirus Genome Synthesis, Rachel Laree Dansereau

Dartmouth College Master’s Theses

Human cytomegalovirus (HCMV) is a large double stranded DNA virus and member of the Herpesviridae family. Like all herpesviruses, HCMV presents with characteristics of persistent, lifelong infections that transition between lytic and latent states. The replication of the viral genome is traditionally thought to occur by a rolling circle mechanism, but this model is supported by little evidence. It is known that HCMV actively recruits several host proteins to viral replication compartments (RCs), including proteins involved in the DNA damage response (DDR). The exact mechanisms of how these proteins are used and in what ways they help the virus remain …

Using The Flexon Approach To Rnai For Analysis Of Gene Function In Gonadal Development In C. Elegans, Andrew D. Spalding

Undergraduate Theses

C. elegans, a nematode worm, was used as a model organism to analyze the developmental effects of knocking down the expression of genes that are both essential to worm viability and highly enriched in reproductive tissues. In earlier research, approximately 70 C. elegans genes were identified that are both gonad-enriched and essential. To prioritize which genes should be the focus of future studies, a new strain of C. elegans was produced with three specific genetic variations that: 1) silence essential, somatic gonad-enriched gene expression, 2) limit the effects of this gene silencing to the gonad, and 3) yield a …

Hormonal, Cytokinetic, And Skeletal Response To A Single Weighted Vest Exercise Treatment: A Pilot Study To Determine Weighted Vest “Rucking” Treatment For Osteoporosis In Post-Menopausal Women, Eleanor Pell

Master's Theses

Osteoporosis is characterized by a deteriorating of bone tissue leading to brittleness and increased fracture risk that affects both men and women as they age. Postmenopausal women are of particular interest due to high risk of declining bone density, a characteristic of this population. Treatments for osteoporosis range from menopause hormone therapy, bisphosphonates, biologics, nutritional changes, and exercise. Load bearing exercise interventions have shown effectiveness for stimulating bone growth, but many factors such as lack of access, motivation, self-confidence or knowledge, prevent long term compliance. “Weighted vest rucking” refers to a variation of rucking, which is a form of exercise …

Investigating The Taxonomic Uncertainties Of Potentilla Rupincola, Natalie Elizabeth Hieber

Master's Theses

Landscape stewardship is an integral role for land managers that becomes more important when rare or endangered species occur within managed areas. Conservation across the landscape is a primary concern for land managers, but resources allocated for conservation can be limited due to many competing goals. Taxonomic uncertainty surrounding rare and endangered taxa, particularly plant taxa, that have historically been classified solely using morphological features further complicates conservation planning. One such taxon is Potentilla rupincola, a rare plant endemic to the eastern Rocky Mountains in Colorado. For over a century, botanists have debated whether P. rupincola is a distinct species …

Developing Warning Signage For Harmful Algal Blooms At Lake Fayetteville, Abigail R. Evans

Biological Sciences Undergraduate Honors Theses

The presence of harmful algal blooms (HABs) poses many risk factors for human health, and once microcystin concentration has reached a certain level, that water source will be closed for the duration of the bloom. Agencies tend to use static signage with limited information to inform the public about the current status of the water, but a sign similar to the one used by the National Fire Danger Rating System can allow for constant updates detailing specific risk levels for the public. Using previously reported data on Lake Fayetteville, thresholds for risk factors that are easily measurable were determined. The …