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Battling Infertility, Shirah Abrahams

The Science Journal of the Lander College of Arts and Sciences

Infertility is a complex condition that affects men and women equally and is defined by failure to achieve pregnancy after a year of trying to conceive. This paper addresses both environmental contributions to infertility, such as the effects of smoking, poor nutrition, and exposure to radiation, as well as biological contributors. Biological factors that contribute to infertility include sperm DNA fragmentation, chromosomal mutations, anovulatory dysfunction, and tubule blockages. This paper delves into various treatment options to improve fertility in both males and females, including medications, lifestyle adaptations, and surgeries. These treatment options can restore and improve ovulatory function, sperm motility …

Full Issue: Volume 18, Number 2, Spring 2025

The Science Journal of the Lander College of Arts and Sciences

Complete .pdf file of Volume 18, Number 2 of The Science Journal of the Lander College of Arts and Sciences. Published Spring 2025.

Does Prenatal Stress Have Prenatal And Life-Long Effects?, Miriam Lavizadeh

The Science Journal of the Lander College of Arts and Sciences

Maternal prenatal stress (MPS) has a unique impact on the developing fetus and the child’s life post birth. Pregnancy is a highly anxious time for a lot of women. Many have pregnancy related concerns as well as overall stress from environmental and societal factors. However, this takes a toll on the fetus’s development which can later cause different cognitive and health outcomes in the child. During a time of stress, one’s HPA axis gets activated causing the release of various hormones, particularly cortisol and catecholamines. These hormones can cross the placental barrier called HSD11B2-11β-hydroxysteroid dehydrogenase 2, exposing the sensitive and …

The Role Of The Gut–Brain Axis In Irritable Bowel Syndrome, Malky Weiss

The Science Journal of the Lander College of Arts and Sciences

The gastrointestinal (GI) system and the brain share a highly integrated relationship mediated by the gut–brain axis, with implications across a range of medical disciplines. Irritable bowel syndrome (IBS) is the most prevalent disorder of gut brain interaction (DGBI) which affects a significant portion of the global population, yet its pathophysiology has historically been poorly understood. This review examines the development and maintenance of IBS, drawing on literary sources to explore the gut–brain axis and disease expression which occurs as a result of its dysfunction. Common pathological features of IBS include visceral hypersensitivity, altered serotonin signaling, inappropriate immune activation, and …

Heterospecific Coprophagy In The White-Tailed Deer Odocoileus Virginianus (Zimmermann, 1780) In Costa Rica, Mora Manuel Jose, Juan De Dios Astorga-Acuña

Biology Faculty Publications and Presentations

Animals may engage in coprophagy, including heterospecific coprophagy, where they consume the feces of other species. The white-tailed deer, Odocoileus virginianus, primarily feeds on plant material, such as tender forbs and shrub shoots. This report documents a case of heterospecific coprophagy by the white-tailed deer in Costa Rica, where two individuals were observed consuming domestic horse feces. The reasons for heterospecific coprophagy in ruminants like the white-tailed deer are unclear. Nutritional supplementation, microbial transfer, or other ecological factors may play a role in this behavior. However, such a behavior also poses risks, including the transmission of diseases and parasites from …

Toll-Like Receptor Signaling In Neurons Modulates C. Elegans Feeding Behavior In A Hunger State-Dependent Manner, Neel Patel, Joseph Rios, Retwika Ganguly, Cindy Mutafoglu, Nour Shalash, Karla Gallardo, Malak Saleh, John Chahine, Emily Kopecky, Gursimran Gujral, Kamya Shah, Christos Suriano

Department of Biology Faculty Scholarship and Creative Works

Animals face the risk of encountering pathogenic microbes while foraging for resources. Assessing the risk of nutrition vs. infection can result in the behavioral regulation of immune processes. Behavioral immunity in the nematode roundworm Caenorhabditis elegans (C. elegans) is regulated, in part, by the innate immune molecule TOL-1: a homolog of vertebrate Toll-like Receptor (TLR) proteins that influences C. elegans pathogen avoidance behaviors by promoting the development of CO2-detecting chemosensory neurons. While TOL-1′s role in pathogen avoidance is well established, its role in an opposing behavior – foraging – has not been examined. In addition to pathogenic bacteria, preferred food …

“Nice To See You”: Addressing Plant Awareness Disparity With Locally Specific Ecological And Cultural Plant Education, Cecilia Muecke

Pomona Senior Theses

Plants form the basis of life on Earth. However, due to the phenomenon of plant awareness disparity, a self-perpetuating cycle whereby plants are overlooked on an individual and global level ensues. Lack of plant awareness leads to a lessened emphasis on plants in sustainability and conservation as well as biology education, resulting in negative impacts on biodiversity and food security. The severity of plant awareness disparity is dependent on cultural context, and Indigenous and/or traditional societies are less likely to experience plant awareness disparity because of they are typically more connected to plants for their everyday needs. Native plants are …

Florida Scrub Is Nuts (And Drupes): Fruit Production And Consumption In Florida’S Fire-Prone, Xeric Uplands, Warren G. Abrahamson Ii

Faculty Journal Articles

This is a story about how plant size, fire, and climate affect fruit and nut production (i.e., mast) in Florida’s fire-prone, xeric uplands and the importance of mast as food for wildlife. To set the stage, let’s first explore the primary mast-producing plants of Florida’s xeric uplands: oaks, hickory, and palmettos.

Larval Environments Affect The Implementation Of The Sterile Insect Technique On Aedes Mosquitoes, Katherine G. Evans

Theses and Dissertations

Sterile Insect Technique (SIT) is an effective method for controlling pests and has been increasing in popularity to control Aedes mosquitoes. SIT involves inundating an area with sterilized male mosquitoes to reduce egg hatch and ultimately the number of wild adults. Previous research indicates that enacting mortality early in the larval life of Aedes mosquitoes can result in counter-productive effects, due to reduced competition among developing larvae. I hypothesize that the effectiveness of SIT at reducing adult populations is modified by densitydependent mortality and density-dependent growth among larvae. I performed two field-to-lab studies and developed an individual-based model to test …

Programming Carcass Composition Through Gestational Nutrition, Sydni Elise Borders

Electronic Theses and Dissertations

The objective of this study was to evaluate the influence of maternal nutrient restriction during mid-gestation on the performance of the dam, feeding performance, carcass composition, and genetic expression in the offspring. Cows (n = 46) were randomly assigned to one of two treatments based on global nutrient intake: 1) fed to achieve and/or maintain a BCS of 5 or 6 (Positive Energy Status [PES]; n = 24) or 2) fed to lose one BCS during 99 days of mid-gestation (Negative Energy Status [NES]; n = 22). Cows in NES had greater decreases (P < 0.05) in body fat stores and muscle mass, elevated NEFA concentrations, and displayed decreased (P < 0.05) DMI, HP, and GHG emissions. There were no differences in milk components or volume produced between treatments (P > 0.05). There were no differences in …

Host-Associated Beneficial Gut Microbiota Boosts Induced Immunity And Limits Immune Deployment Costs In Bumblebees, Austin C. Calhoun, Teni Shosanya, Brenna K. Long, Jade K. Rehberger, Ben M. Sadd

Faculty Publications – Biological Sciences

1. Ecological immunology posits that variation in host resistance to infection may be attributed partly to the ecological and evolutionary costs of immunity. While the deployment of immune defence is necessary to combat pathogenic infection, hosts pay energetic and other costs for activation.
2. Host-associated beneficial microbiota have been shown to affect multiple host traits, including immunity, but how interactions with these microbial communities may mitigate the costs of immune activation remains an open question. For apid bees, including eusocial bumblebees, core members of the adult gut microbiota contribute to a variety of fitness-relevant traits and provide a key ecological and evolutionary …

Behavioral Response Of House Flies (Diptera: Muscidae) To 3 Bittering Agents, Panchalie B. Gunathunga, Bethia H. King, Christopher J. Geden

Faculty Articles, Papers, and Other Scholarship

House flies, Musca domestica L., are pests at livestock facilities. House fly numbers are controlled mainly by manure management and chemical controls, like use of toxic baits. Some toxic baits contain denatonium benzoate as a bittering agent, to avoid poisoning of children. House fly behavioral response to denatonium benzoate was examined, using 2 different diluents, sucrose solution or orange juice. Response of flies to quinine and sucrose octaacetate, 2 other bittering agents, was also examined in sucrose. Sucrose is the sweetener in commercially available toxic house fly baits. The proboscis extension response of both male and female flies was significantly …

Timing Of Migration And Seasonal Movements Of Arctic Grayling (Thymallus Arcticus) In Relation To Water Temperature In The Kakisa River And Upper Mackenzie River, Nwt: Results From An Acoustic Telemetry Study., Levi Snook

Theses and Dissertations (Comprehensive)

Arctic grayling (Thymallus arcticus) are a cold-water salmonid that inhabit waterbodies throughout the circumpolar regions of the northern hemisphere. In the last decade, Ka'a'gee Tu First Nation members as well as local sport fishers, have observed lower catches of Arctic grayling during their annual spawning run in the Kakisa River, NWT. Many potential causes of this decline have been hypothesized including climate change and over harvesting. Outside of the general annual spawning activity in the headwaters of the Kakisa River, the ecology of the population, including post-spawn habitat use and migratory patterns, remained understudied. To address these knowledge gaps, acoustic …

Cultivation Of Winged Kelp (Alaria Marginata) In Humboldt Bay, Evan C. Simpson

Cal Poly Humboldt theses and projects

The cultivation potential of the winged kelp (Alaria marginata) was evaluated in Humboldt Bay, California, to further develop sustainable aquaculture in the region. Seasonality, depth, and system design were evaluated in regard to harvest biomass and quality. Results suggested that single-longline configurations at shallow depths (< 2 m) produced greater total biomass than a multi-longline system, suggesting enhanced water flow and reduced self-shading improved growth. Kelp grew best with a winter outplanting period (December-April), most likely due to environmental conditions (e.g., temperature, nutrients, and salinity) being within the kelp’s tolerable range, with as much as 2.24 kg/meter of kelp being harvested. These findings demonstrate that while the estuarine system has more variable conditions than predicted, A. marginata can be successfully cultivated in Humboldt Bay and highlight its potential as a viable crop for northern California’s emerging seaweed industry. Future work targeting the optimization of single-longline design and deployment timing may further improve yield and support regional goals for sustainable aquaculture and food security.

Journal Of Earth And Life Science, Academic Year 2024-2025, Megan Boche, Nathan D. Pyburn, Ben Hoover, Jayden R. Alsleben, Hector Montoya, Jr, Reed Cumberland, Rose Kuhlmann, Ray Anderson, Ellie Isakson, Seth Sisneros-Martinez, Zanden Mellen, Quady Bernu, Cian Verbridge, Benjamin D. Strei, Madelaine Adamich, Arian Garcia, Tegwen Romportl, Sandra J. Marcu, Bemidji State University

Journal of Earth and Life Science

No abstract provided.

Age Class Is Not Related To Size Or Composition Of Home Ranges Among Suburban White-Tailed Deer During Parturition, Nathan D. Pyburn

Journal of Earth and Life Science

How white-tailed deer use the landscape in an urban environment can help us understand the effects of urbanization on deer populations. White-tailed deer form observable matriarchal hierarchies in studied populations. This study examines the matriarchal structure, home range size, and home range composition of 25 collared white-tailed deer within the city limits of Bemidji, MN. The results found no significant difference between age class and home range size or composition. However, movement metrics from yearling and mature age classes were more similar than the juvenile age class females. I propose this is because social acceptance between mature females was higher …

The Influence Of Flower-Microbe Interactions On Bumble Bee Behavior And Gut Microbiome Composition, Success Chiamaka Ekemezie

Graduate Theses/Dissertations

This thesis examines how microbial interactions in floral nectar and environmental variation influence bumble bee (Bombus spp.) foraging behavior and gut microbiome composition. Pollen germination experiments and behavioral assays in the lab tested whether Metschnikowia reukaufii (yeast) and Acinetobacter nectaris (bacteria) induce pollen germination and bursting in nectar and affect bee behavior subsequently. Both microbes reduced intact pollen, but bees did not alter flower preference. Furthermore, the study also assessed how floral and bee community composition shaped gut microbiome composition across six Missouri prairies. Using amplicon-sequenced fungal ITS and bacterial 16S rRNA genes, I found that fungal microbiome composition varied …

Inoculating Soybean Plants At Different Growth Stages: Selecting Bradyrhizobium, Sinorhizobium, Or Both, Matthew R. Knoll

Graduate Theses/Dissertations

Soybean plants rely on nitrogen for growth, however atmospheric nitrogen (N2) is not a usable form and needs to be converted into different forms that are available to the plant. Nitrogen fixing bacteria such as rhizobia form symbiotic relationships with Soybeans in exchange for shelter and excess plant sugars. As a result, the plant can get the nitrogen it needs. There are four main genera of rhizobia that can form root nodules on Soybean including Bradyrhizobium, Sinorhizobium, Mesorhizobium, and Rhizobium. At this point, the effect that age of the host plant has on the selection of …

Restoration Of Giant River Cane (Arundinaria Gigantea) In Southwest Missouri, Lyndsey D. Rightnowar

Graduate Theses/Dissertations

Giant river cane (Arundinaria gigantea), a native bamboo species, once dominated riparian landscapes across the southeastern United States but has declined to approximately 2% of its historic range. This study evaluated restoration techniques for giant cane in southwest Missouri by examining the influence of rhizome source (putative genotype), planting type, and restoration site on restoration success. I compared two planting types: greenhouse-to-field (G2F) transplanting, where rhizomes were first propagated in the greenhouse before planting, and field-to-field (F2F) transplanting, where rhizomes were directly transplanted from source canebrakes to restoration sites. Rhizomes were collected from four existing canebrakes in Taney …

Testing The Life-History Dependence Of Dietary Restriction Effects On Oxidative Molecular Damage In Hornworms, Fahime Taheri

Masters Theses

DR and ambient temperature are two environmental factors widely implicated in shaping organismal maintenance and longevity through effects on metabolic rate and oxidative damage. This study tests whether DR and reduced body temperature independently or interactively reduce oxidative protein damage in the gut of tobacco hornworm larvae, a short-lived ectotherm whose life history may constrain typical DR responses. Larvae hatched from eggs were allocated to two feeding regimes (AL and DR) and to 20 °C and 30 °C. At a defined endpoint, guts dissected and homogenized, and analyzed for protein carbonyl content and total protein. Protein damage was expressed as …

Biotransformation Of Camelina Meal Via Pretreatment And Fermentation For Functional And Nutritional Upgrading, Ram Kumar Bhattarai

Electronic Theses and Dissertations

Camelina sativa, an oilseed crop of the Brassicaceae family, has seen increased cultivation in North America in response to the rising demand for biofuels over the past two decades. With this growth, camelina meal, a byproduct of oil extraction, has emerged as a promising yet underutilized resource, particularly for applications in animal nutrition. This study aimed to evaluate the potential of camelina meal as a substrate for submerged fungal fermentation and to examine how this bioconversion affects its physicochemical and nutritional properties. The influence of mild pretreatments (unwashed, washed only, and washed/dried and ground) on fermentation outcomes was also assessed. …

Chromosome Segregation Dynamics During Meiosis I, Meiosis Ii, And Mitosis Cell Divisions In Acheta Domesticus (House Crickets), Sweta Aryal

Master’s Theses

Chromosomes exhibit diverse types of organization and movement during the cell division process. Meiosis is essential for sexual reproduction, producing haploid cells from diploid precursors. In meiosis I, homologous chromosomes pair up, and separate in anaphase I, with two chromatids moving toward each pole. In meiosis II, the sister chromatids move to opposite poles during anaphase II and produce haploid cells. In contrast, in mitosis, the chromosomes are copied and distributed to produce genetically identical diploid somatic cells. Understanding the behavior of chromosomes during mitosis and meiosis is significant for accurate chromosome segregation to prevent birth defects and diseases like …

Effects Of Diet Composition On Physical Parameters In Danio Rerio, Isabella Hemphill

Williams Honors College, Honors Research Projects

With the use of zebrafish as a common model organism for human health, the reduction of confounding variables in their care is key. Many commercialized zebrafish diets are available for purchase, but each one consists of a different ratio of these crucial macronutrients. This study aimed to determine the effects long-term diets high in one macronutrient would have on the morphometrics, heart, liver, and protein content of zebrafish. Four diets were fed over a period of almost two years- high lipid, high carb, high protein, and a control diet. The control diet was the standard feed used in this lab, …

The Role Of Fruiting Bodies In Protecting A Community Of Myxococcus Xanthus Spores From The Environment, Dave Lall

Wayne State University Dissertations

Environmental microorganisms have evolved a variety of strategies to survive fluctuations in environmental conditions, including the production of biofilms and differentiation into spores. Myxococcus xanthus are ubiquitous soil bacteria that produce starvation-induced multicellular fruiting bodies filled with environmentally resistant spores (a specialized biofilm). Isolated spores have been shown to be more resistant than vegetative cells to heat, ultraviolet radiation, and desiccation. The evolutionary advantage of producing spores inside of fruiting bodies is not clear. Here, we examine a hypothesis that the fruiting body provides additional protection from environmental insults. We developed a high-throughput method to compare the recovery (outgrowth) of …

Enhancing Alfalfa Persistence In Rangelands: Evaluating Morphological Traits Of Medicago Sativa Subsp. Falcata Germplasm, Abdulallah Mohammed Alomair

Electronic Theses and Dissertations

Rangelands cover nearly half of the Earth’s surface, representing about 54% (79 million km2), and occur in different types and climates worldwide. Alfalfa (Medicago sativa L.) is a major component in rangelands and covers about (320 thousand km2), representing about 0.4% of total global rangeland area. As a critical perennial legume crop, alfalfa can improve soil health by fixing approximately 336 kg/ha/year of nitrogen and sequestering up to 614 kg/ha/year of carbon, while enhancing livestock production due to its high content level of vitamins, magnesium, minerals, fiber, and protein. However, environmental stresses such as drought, freezing, and grazing limit alfalfa …

Pesticide And Pathogen Exposure Causes Idiosyncratic Gene Expression Responses Across Four Diverse North American Bumble Bee Species, Rubén Martín-Blázquez, Sydney A. Cameron, Austin C. Calhoun, James P. Strange, Ben M. Sadd

Faculty Publications – Biological Sciences

Bumble bee (Bombus Latreille) populations of certain species have declined precipitously in North America over several decades. Hypotheses for declines include exposure to the pathogen Nosema bombi and neonicotinoid pesticides. Importantly, populations of some bumble bee species remain stable despite their presumed exposure to these same stressors. We hypothesise that declining and stable species exhibit distinct responses to N. bombi and neonicotinoids, detectable as differential gene expression profiles. To test this, we exposed larvae of Bombus occidentalis (declining) and B. impatiens (stable) to N. bombi and to the neonicotinoid imidacloprid, plus a combination of both. RNA-seq analysis revealed almost …

The Responses Of Insect Herbivores And Local Food Webs To Invasive Shrubs, Logan W. Huber

Browse all Theses and Dissertations

Invasive species cause widespread ecological disruption and economic loss. Invasive plants in particular have the potential to reshape forest food webs from the bottom up. However, the extent to which herbivores colonize and assimilate invasive plants into their diets remains unclear. To address this, I surveyed caterpillar abundance, richness, and herbivory on two invasive shrubs, Lonicera maackii and Elaeagnus umbellata, across regions differing in infestation history. Lonicera maackii supported lower overall caterpillar abundance and richness but hosted a more diverse and abundant caterpillar community in the heavily infested region. E. umbellata supported robust caterpillar communities and experienced herbivory levels comparable …

Diabetes Potentiates The Emergence And Expansion Of Antibiotic Resistance, John C. Shook, Benjamin P. Darwitz, Kaleb J. Tyson, Amanda Z. Velez, Sophia K. Bridwell, Joshua B. Parsons, Sarah E. Rowe, Christopher Marshall, Brian P. Conlon, Lance R. Thurlow

Biological Sciences Faculty Research and Publications

Individuals with diabetes mellitus frequently develop severe skin and soft tissue infections (SSTIs) that are recalcitrant to antibiotic treatment. We examined how diabetes affects the emergence of antibiotic resistance in a Staphylococcus aureus SSTI. We determined that S. aureus evolves antibiotic resistance rapidly in diabetic mice, while resistance did not occur in nondiabetic mice over the course of infection. Diabetes-associated immune cell dysfunction plays a minor role in the emergence of resistance, while hyperglycemia plays a dominant role facilitating the expansion and takeover of resistant mutants in diabetic infections. Furthermore, vancomycin intermediate resistant isolates display a pronounced fitness defect in …

Diversity, Genomics And Antimicrobial Resistance Of Coagulase-Negative Staphylococcus: A Literature Review, Kathleen Okeefe

Electronic Theses & Dissertations (2024 - present)

Members of the gram-positive bacterial genus Staphylococcus have historically been classified into coagulase-positive Staphylococcus (CoPS) and coagulase-negative Staphylococcus (CoNS). This classification is based on the ability of clotting of plasma by the coagulase enzyme, which converts fibrinogen to fibrin. CoNS species are ubiquitous commensals that frequently colonize the skin and mucosal surfaces. They are also opportunistic pathogens implicated in many human and animal infections. The evolutionary history of CoNS has generally been overlooked because of the historical lack of recognition for their clinical importance and poor taxonomic sampling. They are often perceived as being less or non-pathogenic, especially compared to …

Methyl-Cpg-Binding Domain As A Protein Interaction Partner In Promoter Regulation And Neurodevelopment Through Evolutionary Expanded Entanglement, Stephanie M. Bilinovich, Surya B. Chhetri, Jackson T. Mitchell, Gage O. Leighton, Vladislav Jdanov, Jacob K. Zieba, Taylor W. Cook, Krysta L. Engel, Robert M. Vaughan, Humza Bhatti, Sadie L. Heeringa, Amy M. Wilstermann, Sophie Vanderweele, Akansha S. Das, Emily C. Sherry, Stephen A. Duncan, Katie L. Uhl, David C. Hinds, Mark Mackiewicz, Sarah K. Meadows, Kimberly M. Newberry, E. Christopher Partridge, Sara G. Cline, C. Joy Shepard, D. Casey Smith, Antonio Bradley, Daniel Vogt, Daniel B. Campbell, Lucas Pozzo-Miller, Caleb P. Bupp, Austin J. Goodyke, Surender Rajasekaran, Rebecca C. Knickmeyer, Benjie Blair

Research, Publications & Creative Work

There is increasing evidence that the methyl-binding domain (MBD) is a protein-protein interaction motif that can function independently of methylated DNA binding. The MBD proteins found throughout plants and invertebrates duplicated into multiple vertebrate DNA and non-DNA-binding members (MBD1, MBD2, MBD3, MBD4, MBD5, MBD6, MECP2, BAZ2A, BAZ2B, SETDB1, andSETDB2). Although many invertebrate species possess MBD proteins that can bind and recognize DNA methylation, the DNA-binding function has been independently lost multiple times, with only minor alterations to the protein interaction residues. The nucleosome remodeling and deacetylase (NuRD) complex, which interacts with MBD2/3 and is colocalized with MBD1/4 ChIP-Seq, is maintained …