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Effects Of Predation Risk, Density And Disease On Energy Efficiency In A Larval Anuran, Sarah Crane Apr 2008

Effects Of Predation Risk, Density And Disease On Energy Efficiency In A Larval Anuran, Sarah Crane

Theses and Dissertations

Predation, density and disease affect behavior, morphology and growth. There is a lack of information on how these changes relate to efficiency of energy transfer in anuran larvae, although previous studies suggest that predation should decrease and competition should increase efficiency. Using a 2 x 2 factorial design, we manipulated predation presence and larval density to test how predation risk and density affect energy efficiency. During the experiment, approximately half of the tadpoles were infected by an unknown disease. Neither predation risk nor density affected assimilation or growth efficiency, despite changes in growth and development. Disease, however, decreased gut length …


Assessment Of A Non-Invasive High-Throughput Classifier For Behaviours Associated With Sleep And Wake In Mice, Kevin D. Donohue, Dharshan C. Medonza, Eli R. Crane, Bruce F. O'Hara Apr 2008

Assessment Of A Non-Invasive High-Throughput Classifier For Behaviours Associated With Sleep And Wake In Mice, Kevin D. Donohue, Dharshan C. Medonza, Eli R. Crane, Bruce F. O'Hara

Biology Faculty Publications

This work presents a non-invasive high-throughput system for automatically detecting characteristic behaviours in mice over extended periods of time, useful for phenotyping experiments. The system classifies time intervals on the order of 2 to 4 seconds as corresponding to motions consistent with either active wake or inactivity associated with sleep. A single Polyvinylidine Difluoride (PVDF) sensor on the cage floor generates signals from motion resulting in pressure. This paper develops a linear classifier based on robust features extracted from normalized power spectra and autocorrelation functions, as well as novel features from the collapsed average (autocorrelation of complex spectrum), which characterize …


Genome Size Scaling Through Phenotype Space, Charles A. Knight, Jeremy M. Beaulieu Apr 2008

Genome Size Scaling Through Phenotype Space, Charles A. Knight, Jeremy M. Beaulieu

Biological Sciences

Background and Aims Early observations that genome size was positively correlated with cell size formed the basis of hypothesized consequences of genome size variation at higher phenotypic scales. This scaling was supported by several studies showing a positive relationship between genome size and seed mass, and various metrics of growth and leaf morphology. However, many of these studies were undertaken with limited species sets, and often performed within a single genus. Here we seek to generalize the relationship between genome size and the phenotype by examining eight phenotypic traits using large cross-species comparisons involving diverse assemblages of angiosperm and gymnosperm …


Maternal Effects Of Carotenoid Consumption In Guppies (Poecilia Reticulata), Gregory F. Grether, Gita R. Kolluru, K. Lin, M. A. Quiroz, G. Robertson, A. J. Snyder Apr 2008

Maternal Effects Of Carotenoid Consumption In Guppies (Poecilia Reticulata), Gregory F. Grether, Gita R. Kolluru, K. Lin, M. A. Quiroz, G. Robertson, A. J. Snyder

Biological Sciences

1. Carotenoids transferred from mother to offspring may enhance the quality of the offspring. Whether such maternal effects occur in guppies (Poecilia reticulata) has an important bearing on mate preference evolution.
2. By raising female guppies from birth on different dietary carotenoid levels, we examined the pattern of carotenoid allocation to maternal tissue (skin) vs. eggs. Skin carotenoid content was only weakly affected by carotenoid intake while egg carotenoid content was strongly affected.
3. We then tested for effects of maternal carotenoid intake on several measures of offspring quality, including size and condition at birth, juvenile growth rate, …


The Role Of Estrogen Receptor Alpha In Neonatal Oocyte Development, Jemella C. Raymore Apr 2008

The Role Of Estrogen Receptor Alpha In Neonatal Oocyte Development, Jemella C. Raymore

Renée Crown University Honors Thesis Projects - All

The development of primordial germ cells into oocytes is important for mammalian reproduction. Female germ cells first undergo a number of cell divisions resulting in the formation of cysts. Germ cell cysts are clusters of cells connected by intercellular bridges, formed by incomplete cytokinesis. The cysts breakdown after birth, resulting in individual oocytes that become surrounded by somatic pre-granulosa cells to form primordial follicles. During cyst breakdown two thirds of the original population of oocytes die. However, the processes by which cells within the cyst are designated to survive or die is not yet known. In addition, it is not …


Lack Of Respiratory Effects Of Nicotine Applied To The Caudal Medullary Raphã©, Nicole Bates Apr 2008

Lack Of Respiratory Effects Of Nicotine Applied To The Caudal Medullary Raphã©, Nicole Bates

Biology Theses - Archive

Breathing is an involuntary and automatic process initiated by a network of neurons within the brainstem. These neurons are affected by a number of factors (mechanical, electrical and chemical) that help modulate the frequency and pattern of breathing. Three respiratory chemosensitive sites have traditionally been described on the ventral medullary surface. These sites are affected by the pH of the cerebrospinal fluid (CSF) bathing the brain and by chemicals dissolved within the CSF. More recently, additional sites have been described with chemosensitive activity and of these the medullary raphé has received the most attention. Although the dangers of smoking is …


Production Of Cftr-Null And Cftr-Δf508 Heterozygous Pigs By Adeno-Associated Virus - Mediated Gene Targeting And Somatic Cell Nuclear Transfer, Christopher S. Rogers, Yanhong Hao, Tatiana Rokhlina, Melissa Samuel, David A. Stoltz, Yuhong Li, Elena Petroff, Daniel W. Vermeer, Amanda C. Kabel, Ziying Yan, Lee Spate, David Wax, Clifton N. Murphy, August Rieke, Kristin Whitworth, Michael L. Linville, Scott W. Korte, John F. Engelhardt, Michael J. Welsh, Randall S. Prather Apr 2008

Production Of Cftr-Null And Cftr-Δf508 Heterozygous Pigs By Adeno-Associated Virus - Mediated Gene Targeting And Somatic Cell Nuclear Transfer, Christopher S. Rogers, Yanhong Hao, Tatiana Rokhlina, Melissa Samuel, David A. Stoltz, Yuhong Li, Elena Petroff, Daniel W. Vermeer, Amanda C. Kabel, Ziying Yan, Lee Spate, David Wax, Clifton N. Murphy, August Rieke, Kristin Whitworth, Michael L. Linville, Scott W. Korte, John F. Engelhardt, Michael J. Welsh, Randall S. Prather

Department of Biology Faculty Scholarship and Creative Works

Progress toward understanding the pathogenesis of cystic fibrosis (CF) and developing effective therapies has been hampered by lack of a relevant animal model. CF mice fail to develop the lung and pancreatic disease that cause most of the morbidity and mortality in patients with CF. Pigs may be better animals than mice in which to model human genetic diseases because their anatomy, biochemistry, physiology, size, and genetics are more similar to those of humans. However, to date, gene-targeted mammalian models of human genetic disease have not been reported for any species other than mice. Here we describe the first steps …


The Mayfly Newsletter, Peter M. Grant Apr 2008

The Mayfly Newsletter, Peter M. Grant

The Mayfly Newsletter

The Mayfly Newsletter is the official newsletter of the Permanent Committee of the International Conferences on Ephemeroptera.


The Dynamic Nature Of Eukaryotic Genomes, Laura Wegener Parfrey, Daniel J.G. Lahr, Laura A. Katz Apr 2008

The Dynamic Nature Of Eukaryotic Genomes, Laura Wegener Parfrey, Daniel J.G. Lahr, Laura A. Katz

Biological Sciences: Faculty Publications

Analyses of diverse eukaryotes reveal that genomes are dynamic, sometimes dramatically so. In numerous lineages across the eukaryotic tree of life, DNA content varies within individuals throughout life cycles and among individuals within species. Discovery of examples of genome dynamism is accelerating as genome sequences are completed from diverse eukaryotes. Though much is known about genomes in animals, fungi, and plants, these lineages represent only 3 of the 60-200 lineages of eukaryotes. Here, we discuss diverse genomic strategies in exemplar eukaryotic lineages, including numerous microbial eukaryotes, to reveal dramatic variation that challenges established views of genome evolution. For example, in …


The Effects Of Epidermal Growth Factor And Basic Fibroblast Growth Factor On Cryopreserved Human Adipose Derived Stem Cells In Culture: Proliferation, Adipogenesis, And Osteogenesis, Teddi Leigh Hebert Apr 2008

The Effects Of Epidermal Growth Factor And Basic Fibroblast Growth Factor On Cryopreserved Human Adipose Derived Stem Cells In Culture: Proliferation, Adipogenesis, And Osteogenesis, Teddi Leigh Hebert

Honors Capstones

No abstract provided.


Responses Of The Sea Catfish, Ariopsis Felis, To Chemical Defenses From The Sea Hare, Aplysia Californica, Sheybani Arman Apr 2008

Responses Of The Sea Catfish, Ariopsis Felis, To Chemical Defenses From The Sea Hare, Aplysia Californica, Sheybani Arman

Honors Capstones

No abstract provided.


Chromosomes And Expression Mechanisms: Bringing Together The Roles Of Dna, Rna And Proteins, Moshe Yaniv, Sarah C.R. Elgin Apr 2008

Chromosomes And Expression Mechanisms: Bringing Together The Roles Of Dna, Rna And Proteins, Moshe Yaniv, Sarah C.R. Elgin

Biology Faculty Research

No abstract provided.


Novel Weapons: Invasive Plant Suppresses Fungal Mutualists In America But Not In Its Native Europe, Ragan M. Callaway, Don Cipollini, Kathryn Barto, Giles C. Thelen, Steven G. Hallett, Daniel Prati, Kristina Stinson, John Klironomos Apr 2008

Novel Weapons: Invasive Plant Suppresses Fungal Mutualists In America But Not In Its Native Europe, Ragan M. Callaway, Don Cipollini, Kathryn Barto, Giles C. Thelen, Steven G. Hallett, Daniel Prati, Kristina Stinson, John Klironomos

Biological Sciences Faculty Publications

Why some invasive plant species transmogrify from weak competitors at home to strong competitors abroad remains one of the most elusive questions in ecology. Some evidence suggests that disproportionately high densities of some invaders are due to the release of biochemicals that are novel, and therefore harmful, to naïve organisms in their new range. So far, such evidence has been restricted to the direct phytotoxic effects of plants on other plants. Here we found that one of North America's most aggressive invaders of undisturbed forest understories, Alliaria petiolata (garlic mustard) and a plant that inhibits mycorrhizal fungal mutualists of North …


Characterization Of Sox Family Members In Sponge Stem Cells And During Development, Karen E. Leeds Apr 2008

Characterization Of Sox Family Members In Sponge Stem Cells And During Development, Karen E. Leeds

Honors Theses

Sponges are considered the oldest and most basal part of the metazoan lineage and therefore possess a unique set of gene families that are highly conserved among all animals. One of these gene families is known as Sox transcription factors. Sox genes are known to play important roles in complex animals such as the specification of the primary layers of the body, determination of sex, and most recently induction of induced pluirpotent stem cells (iPS cells) from both human and mouse fibroblasts with the help of three other transcription factors. We have found that two different demosponge species Halichondria bowerbanki …


A New Reproductive Mode In The Genus Melanzophryniscus Gallardo, 1961 (Anura: Bufonidae) With Description Of A New Species From The State Of Paraná, Brazil, José A. Langone, Magno V. Segallo, Marcos Bornschein, Rafael O. De Sá Apr 2008

A New Reproductive Mode In The Genus Melanzophryniscus Gallardo, 1961 (Anura: Bufonidae) With Description Of A New Species From The State Of Paraná, Brazil, José A. Langone, Magno V. Segallo, Marcos Bornschein, Rafael O. De Sá

Biology Faculty Publications

A new species of bufonid toad of the genus Melanophryniscus is described from a mountaintop that is part of the Serra do Mar in the northeastern State of Paraná, Brazil. Melanophryniscus alipioi sp. nov. is distinguished from other known species by its uniformly dark brown dorsal color and a unique breeding site. The new species reproduces in bromeliads, a reproductive mode previously unknown for this genus. This species might be susceptible to current habitat lost.


The Effect Of Dexmedetomidine On The Mini-Cog Score And High-Mobility Group Box 1 Levels In Elderly Patients With Postoperative Neurocognitive Disorders Undergoing Orthopedic Surgery, Joan M Mastrobattista, Mark A Klebanoff, J Christopher Carey, John C Hauth, Cora A Macpherson, J Ernest, Margaret Cotroneo, Kenneth J Leveno, Ronald Wapner, Michael Varner, Jay D Iams, Atef Moawad, Baha M Sibai, Menachem Miodovnik, Mitchell Dombrowski, Mary J O'Sullivan, J Peter Vandorsten, Oded Langer Apr 2008

The Effect Of Dexmedetomidine On The Mini-Cog Score And High-Mobility Group Box 1 Levels In Elderly Patients With Postoperative Neurocognitive Disorders Undergoing Orthopedic Surgery, Joan M Mastrobattista, Mark A Klebanoff, J Christopher Carey, John C Hauth, Cora A Macpherson, J Ernest, Margaret Cotroneo, Kenneth J Leveno, Ronald Wapner, Michael Varner, Jay D Iams, Atef Moawad, Baha M Sibai, Menachem Miodovnik, Mitchell Dombrowski, Mary J O'Sullivan, J Peter Vandorsten, Oded Langer

Faculty, Staff and Student Publications

Our objective was to determine the effect of body mass index (BMI) on response to bacterial vaginosis (BV) treatment. A secondary analysis was conducted of two multicenter trials of therapy for BV and TRICHOMONAS VAGINALIS. Gravida were screened for BV between 8 and 22 weeks and randomized between 16 and 23 weeks to metronidazole or placebo. Of 1497 gravida with asymptomatic BV and preconceptional BMI, 738 were randomized to metronidazole; BMI was divided into categories: < 25, 25 to 29.9, and > or = 30. Rates of BV persistence at follow-up were compared using the Mantel-Haenszel chi square. Multiple logistic regression was used to evaluate the effect …


Systems Approach Identifies An Organic Nitrogen-Responsive Gene Network That Is Regulated By The Master Clock Control Gene Cca1, Rodrigo A. Gutierrez, Trevor L. Stokes, Karen Thum, Xiaodong Xu, Mariana Obertello, Manpreet S. Katari, Milos Tanurdzic, Alexis Dean, Damion C. Nero, C Robertson Mcclung, Gloria M. Coruzzi Mar 2008

Systems Approach Identifies An Organic Nitrogen-Responsive Gene Network That Is Regulated By The Master Clock Control Gene Cca1, Rodrigo A. Gutierrez, Trevor L. Stokes, Karen Thum, Xiaodong Xu, Mariana Obertello, Manpreet S. Katari, Milos Tanurdzic, Alexis Dean, Damion C. Nero, C Robertson Mcclung, Gloria M. Coruzzi

Dartmouth Scholarship

Understanding how nutrients affect gene expression will help us to understand the mechanisms controlling plant growth and development as a function of nutrient availability. Nitrate has been shown to serve as a signal for the control of gene expression in Arabidopsis. There is also evidence, on a gene-by-gene basis, that downstream products of nitrogen (N) assimilation such as glutamate (Glu) or glutamine (Gln) might serve as signals of organic N status that in turn regulate gene expression. To identify genome-wide responses to such organic N signals, Arabidopsis seedlings were transiently treated with ammonium nitrate in the presence or absence of …


All I Really Needed To Know I Learned During Gastrulation, Scott F. Gilbert Mar 2008

All I Really Needed To Know I Learned During Gastrulation, Scott F. Gilbert

Biology Faculty Works

No abstract provided.


Lack Of Pathology In A Triple Transgenic Mouse Model Of Alzheimer’S Disease After Overexpression Of The Anti-Apoptotic Protein Bcl-2, Troy T. Rohn, Veera Vyas, Tatiana Hernandez-Estrada, Kathryn E. Nichol, Lori-Ann Christie, Elizabeth Head Mar 2008

Lack Of Pathology In A Triple Transgenic Mouse Model Of Alzheimer’S Disease After Overexpression Of The Anti-Apoptotic Protein Bcl-2, Troy T. Rohn, Veera Vyas, Tatiana Hernandez-Estrada, Kathryn E. Nichol, Lori-Ann Christie, Elizabeth Head

Biology Faculty Publications and Presentations

Alzheimer’s disease (AD) is characterized by the accumulation of plaques containing ß-amyloid (Aß) and neurofibrillary tangles (NFTs) consisting of modified tau. Although Aß deposition is thought to precede the formation of NFTs in AD, the molecular steps connecting these two pathologies is not known. Previous studies have suggested that caspase activation plays an important role in promoting the pathology associated with AD. To further understand the contribution of caspases in disease progression, a triple transgenic Alzheimer’s mouse model overexpressing the anti-apoptotic protein Bcl-2 was generated. Here we show that overexpression of Bcl-2 limited caspase-9 activation and reduced the caspase cleavage …


Dimethylsulfoniopropionate As A Foraging Cue For Reef Fishes, Jennifer L. Debose, Sean C. Lema, Gabrielle A. Nevitt Mar 2008

Dimethylsulfoniopropionate As A Foraging Cue For Reef Fishes, Jennifer L. Debose, Sean C. Lema, Gabrielle A. Nevitt

Biological Sciences

No abstract provided.


Double-Stranded Rna-Activated Protein Kinase Pkr Of Fishes And Amphibians: Varying The Number Of Double-Stranded Rna Binding Domains And Lineage-Specific Duplications, Loubna Tazi, Stefan Rothenburg, Nikolaus Deigendesch, Madhusudan Dey, Thomas E. Dever Mar 2008

Double-Stranded Rna-Activated Protein Kinase Pkr Of Fishes And Amphibians: Varying The Number Of Double-Stranded Rna Binding Domains And Lineage-Specific Duplications, Loubna Tazi, Stefan Rothenburg, Nikolaus Deigendesch, Madhusudan Dey, Thomas E. Dever

Faculty Publications

Double-stranded (ds) RNA, generated during viral infection, binds and activates the mammalian anti-viral protein kinase PKR, which phosphorylates the translation initiation factor eIF2alpha leading to the general inhibition of protein synthesis. Although PKR-like activity has been described in fish cells, the responsible enzymes eluded molecular characterization until the recent discovery of goldfish and zebrafish PKZ, which contain Z-DNA-binding domains instead of dsRNA-binding domains (dsRBDs). Fish and amphibian PKR genes have not been described so far. Results- Here we report the cloning and identification of 13 PKR genes from 8 teleost fish and amphibian species, including zebrafish, demonstrating the coexistence of …


Rotation Of Visual Landmark Cues Influences The Spatial Response Profile Of Hippocampal Neurons In Freely-Moving Homing Pigeons, Gerald E. Hough, Vernon P. Bingman Mar 2008

Rotation Of Visual Landmark Cues Influences The Spatial Response Profile Of Hippocampal Neurons In Freely-Moving Homing Pigeons, Gerald E. Hough, Vernon P. Bingman

College of Science & Mathematics Departmental Research

Pigeon hippocampal neurons display two spatial response profiles: location fields frequently at goals, and path fields connecting goals. We recorded from 15 location and six path cells, with color cues positioned near four goal locations. Following color cue rotation, most location cells (12/15) shifted their response fields; path cells (5/6) lost their fields. Therefore, local visual cues can independently define a reference frame for location cells, but path cells may be more broadly tuned to context or alternative reference frames.


Obestatin Inhibits Vasopressin Secretion: Evidence For A Physiological Action In The Control Of Fluid Homeostasis, Willis K. Samson, Gina L.C. Yosten, Jaw Kang Chang, Alastair V. Ferguson, Meghan M. White Mar 2008

Obestatin Inhibits Vasopressin Secretion: Evidence For A Physiological Action In The Control Of Fluid Homeostasis, Willis K. Samson, Gina L.C. Yosten, Jaw Kang Chang, Alastair V. Ferguson, Meghan M. White

Biological Sciences Faculty Research & Creative Works

Obestatin, a product of post-translational processing of the ghrelin prohormone, has been reported to act in the brain to inhibit thirst. We extended our initial studies on water drinking by examining the effects of obestatin on hypovolemia-induced water and saline drinking and vasopressin release in male rats. Intracerebroventricular administration of obestatin significantly inhibited water, but not saline (0-3 M NaCl) drinking in response to a hypovolemic challenge. Obestatin also inhibited, in a dose-related fashion, dehydration-induced vasopressin secretion without affecting plasma oxytocin levels. Vasopressin release induced by central angiotensin II administration was attenuated significantly by prior administration of obestatin. Finally, central …


Phospholipase Dα3 Is Involved In The Hyperosmotic Response In Arabidopsis, Xuemin Wang, Yueyun Hong, Xiangqing Pan, Ruth Welti Mar 2008

Phospholipase Dα3 Is Involved In The Hyperosmotic Response In Arabidopsis, Xuemin Wang, Yueyun Hong, Xiangqing Pan, Ruth Welti

Biology Department Faculty Works

Rapid activation of phospholipase D (PLD), which hydrolyzes membrane lipids to generate phosphatidic acid (PA), occurs under various hyperosmotic conditions, including salinity and water deficiency. The Arabidopsis thaliana PLD family has 12 members, and the function of PLD activation in hyperosmotic stress responses has remained elusive. Here, we show that knockout (KO) and overexpression (OE) of previously uncharacterized PLDα3 alter plant response to salinity and water deficit. PLDα3 uses multiple phospholipids as substrates with distinguishable preferences, and alterations of PLDα3 result in changes in PA level and membrane lipid composition. PLDα3-KO plants display increased sensitivities to salinity and water deficiency …


Indirect Effects And Traditional Trophic Cascades: A Test Involving Wolves, Coyotes, And Pronghorn, Kim Murray Berger, Eric M. Gese, Joel Berger Mar 2008

Indirect Effects And Traditional Trophic Cascades: A Test Involving Wolves, Coyotes, And Pronghorn, Kim Murray Berger, Eric M. Gese, Joel Berger

Biological Sciences Faculty Publications

The traditional trophic cascades model is based on consumer - resource interactions at each link in a food chain. However, trophic-level interactions, such as mesocarnivore release resulting from intraguild predation, may also be important mediators of cascades. From September 2001 to August 2004, we used spatial and seasonal heterogeneity in wolf distribution and abundance in the southern Greater Yellowstone Ecosystem to evaluate whether mesopredator release of coyotes ( Canis latrans), resulting from the extirpation of wolves ( Canis lupus), accounts for high rates of coyote predation on pronghorn ( Antilocapra americana) fawns observed in some areas. Results of this ecological …


Riding The Wave: Reconciling The Roles Of Disease And Climate Change In Amphibian Declines, Michael W. Sears, Karen R. Lips, Jay Diffendorfer, Joseph R. Mendelson Mar 2008

Riding The Wave: Reconciling The Roles Of Disease And Climate Change In Amphibian Declines, Michael W. Sears, Karen R. Lips, Jay Diffendorfer, Joseph R. Mendelson

Publications

Once introduced, diseases may spread quickly through new areas, infecting naive host populations, such as has been documented in Ebola virus in African primates or rabies in North American mammals. What drives the spread of the pathogenic fungus Batrachochytrium dendrobatidis (Bd), which causes chytridiomycosis, is of particular concern because it has contributed to the global
decline of amphibians. We modeled the spatiotemporal pattern of the loss of upland amphibian populations in Central and South America as a proxy for the arrival of Bd and found that amphibian declines in Central and South America are best explained by Bd spreading through …


Arabidopsis Trithorax1 Dynamically Regulates Flowering Locus C Activation Via Histone 3 Lysine 4 Trimethylation, Stephane Pien, Delphine Fleury, Joshua S. Mylne, Pedro Crevillen, Dirk Inze, Zoya Avramova, Caroline Dean, Ueli Grossniklaus Mar 2008

Arabidopsis Trithorax1 Dynamically Regulates Flowering Locus C Activation Via Histone 3 Lysine 4 Trimethylation, Stephane Pien, Delphine Fleury, Joshua S. Mylne, Pedro Crevillen, Dirk Inze, Zoya Avramova, Caroline Dean, Ueli Grossniklaus

School of Biological Sciences: Faculty Publications

Trithorax function is essential for epigenetic maintenance of gene expression in animals, but little is known about trithorax homologs in plants. ARABIDOPSIS TRITHORAX1 (ATX1) was shown to be required for the expression of homeotic genes involved in flower organogenesis. Here, we report a novel function of ATX1, namely, the epigenetic regulation of the floral repressor FLOWERING LOCUS C (FLC). Downregulation of FLC accelerates the transition from vegetative to reproductive development in Arabidopsis thaliana. In the atx1 mutant, FLC levels are reduced and the FLC chromatin is depleted of trimethylated, but not dimethylated, histone 3 lysine 4, suggesting a specific …


A Songbird Forebrain Area Potentially Involved In Auditory Discrimination And Memory Formation, Raphael Pinaud, Thomas A. Terleph Mar 2008

A Songbird Forebrain Area Potentially Involved In Auditory Discrimination And Memory Formation, Raphael Pinaud, Thomas A. Terleph

Biology Faculty Publications

Songbirds rely on auditory processing of natural communication signals for a number of social behaviors, including mate selection, individual recognition and the rare behavior of vocal learning - the ability to learn vocalizations through imitation of an adult model, rather than by instinct. Like mammals, songbirds possess a set of interconnected ascending and descending auditory brain pathways that process acoustic information and that are presumably involved in the perceptual processing of vocal communication signals. Most auditory areas studied to date are located in the caudomedial forebrain of the songbird and include the thalamo-recipient field L (subfields L1, L2 and L3), …


Broadly Sampled Multigene Trees Of Eukaryotes, Hwan Su Yoon, Jessica Grant, Yonas I. Tekle, Min Wu, Benjamin C. Chaon, Jeffrey C. Cole, John M. Logsdon, David J. Patterson, Debashish Bhattacharya, Laura A. Katz Feb 2008

Broadly Sampled Multigene Trees Of Eukaryotes, Hwan Su Yoon, Jessica Grant, Yonas I. Tekle, Min Wu, Benjamin C. Chaon, Jeffrey C. Cole, John M. Logsdon, David J. Patterson, Debashish Bhattacharya, Laura A. Katz

Biological Sciences: Faculty Publications

Background. Our understanding of the eukaryotic tree of life and the tremendous diversity of microbial eukaryotes is in flux as additional genes and diverse taxa are sampled for molecular analyses. Despite instability in many analyses, there is an increasing trend to classify eukaryotic diversity into six major supergroups: the 'Amoebozoa', 'Chromalveolata', 'Excavata', 'Opisthokonta', 'Plantae', and 'Rhizaria'. Previous molecular analyses have often suffered from either a broad taxon sampling using only single-gene data or have used multigene data with a limited sample of taxa. This study has two major aims: (1) to place taxa represented by 72 sequences, 61 of which …


Variation In Molybdenum Content Across Broadly Distributed Populations Of Arabidopsis Thaliana Is Controlled By A Mitochondrial Molybdenum Transporter (Mot1), Ivan Baxter, Balasubramaniam Muthukumar, Hyeong Cheol Park, Peter Buchner, Brett Lahner, John Danku, Keyan Zhao, Joohyun Lee, Malcolm J. Hawkesford, Mary Lou Guerinot, David E. Salt Feb 2008

Variation In Molybdenum Content Across Broadly Distributed Populations Of Arabidopsis Thaliana Is Controlled By A Mitochondrial Molybdenum Transporter (Mot1), Ivan Baxter, Balasubramaniam Muthukumar, Hyeong Cheol Park, Peter Buchner, Brett Lahner, John Danku, Keyan Zhao, Joohyun Lee, Malcolm J. Hawkesford, Mary Lou Guerinot, David E. Salt

Dartmouth Scholarship

Molybdenum (Mo) is an essential micronutrient for plants, serving as a cofactor for enzymes involved in nitrate assimilation, sulfite detoxification, abscisic acid biosynthesis, and purine degradation. Here we show that natural variation in shoot Mo content across 92 Arabidopsis thaliana accessions is controlled by variation in a mitochondrially localized transporter (Molybdenum Transporter 1 - MOT1) that belongs to the sulfate transporter superfamily. A deletion in the MOT1 promoter is strongly associated with low shoot Mo, occurring in seven of the accessions with the lowest shoot content of Mo. Consistent with the low Mo phenotype, MOT1 expression in low Mo accessions …