Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Biology

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 15781 - 15810 of 20428

Full-Text Articles in Entire DC Network

Evolution Of Craniofacial Architecture And Lateralization In Perissodini Scale-Eaters, Thomas A. Stewart May 2009

Evolution Of Craniofacial Architecture And Lateralization In Perissodini Scale-Eaters, Thomas A. Stewart

Renée Crown University Honors Thesis Projects - All

To understand the evolution of craniofacial asymmetry within the Perissodini tribe, a group of scale-eating fish found in Lake Tanganyika, we performed shape analysis on their craniofacial architecture, and applied a simple lever model to measure asymmetry in lower-jaw mechanics. We found that craniofacial asymmetries were the consequence of sided differences in size and shape of craniofacial elements, and that sided differences in shape predict the lateralization of force and speed of the lower jaw in derived species. Quantitative Trait Locus analysis in Lake Malawi cichlids identified a single locus of major effect for jaw laterality, the first genetic marker …


The Evolution Of Skull Form And Function Among The East African Cichlids Of Lakes Malawi, Victoria, And Tanganyika, Alyssa Mcintyre May 2009

The Evolution Of Skull Form And Function Among The East African Cichlids Of Lakes Malawi, Victoria, And Tanganyika, Alyssa Mcintyre

Renée Crown University Honors Thesis Projects - All

An animal’s skeletal and muscular structures form a biological machine capable of interacting with its environment. When anatomical form changes the resulting modification in biomechanical function can allow it to occupy a new ecological niche. The cichlid fishes of the major East African Rift Lakes have been frequently regarded as one of the best know examples of adaptive radiations that have produced a large variety of skull shapes in an unusually short span of evolutionary time that has permitted the use of an extremely wide variety of feeding niches. I studied the anatomical diversity of this incredible lineage by dissecting …


The Geographic Distribution Of Polyploidy In A Pacific Northwest Plant, Megan A. Larson May 2009

The Geographic Distribution Of Polyploidy In A Pacific Northwest Plant, Megan A. Larson

Renée Crown University Honors Thesis Projects - All

Polyploidy is an important evolutionary mechanism of speciation in plants. Because polyploids may evolve cryptically, there can be several levels of ploidy in a species. The distribution of polyploid species is the first step in understanding the role of polyploidy in plant speciation. I examined the geographic distribution of polyploidy in Heuchera cylindrica (Saxifragaceae) by using flow cytometry to determine the ploidy level of 595 individuals from 39 populations spread across the geographic range of the species. Only single cytotype populations of diploids or tetraploids were found, and no triploids were observed. In contrast to other studies of polyploid distribution, …


Characterization Of The Human Mixed Lineage Leukemia Protein Homolog Set1 In Saccharomyces Cerevisiae, Illona Savich May 2009

Characterization Of The Human Mixed Lineage Leukemia Protein Homolog Set1 In Saccharomyces Cerevisiae, Illona Savich

Renée Crown University Honors Thesis Projects - All

Abstract not Included


A Community Ecology And Stable Isotope Study Of Plankton, Macroinvertebrate, And Fish Communities Surrounding Groundwater Vents In Lake Huron, Michigan, Thomas Garrison Sanders Jr. May 2009

A Community Ecology And Stable Isotope Study Of Plankton, Macroinvertebrate, And Fish Communities Surrounding Groundwater Vents In Lake Huron, Michigan, Thomas Garrison Sanders Jr.

Masters Theses

Extreme environments can create ecotones with uncharacteristic physicochemical conditions and ecological communities. Recently, several submerged sinkholes were discovered in Lake Huron where hypoxic groundwater that is rich with dissolved ions intrudes into surrounding lake water. Researchers have documented large growths of cyanobacteria and chemosynthetic bacteria surrounding these groundwater vents, but little is known if this production is utilized by upper trophic level organisms and how the environmental conditions affect local community density and diversity. My objectives were threefold: (1) I wanted to confirm the presence and describe the nature and extent of chemical and physical gradients in the sublacustrine sinkhole …


Ecological Facilitation May Drive Major Evolutionary Transitions, Zaal Kikvidze, Ragan M. Callaway May 2009

Ecological Facilitation May Drive Major Evolutionary Transitions, Zaal Kikvidze, Ragan M. Callaway

Biological Sciences Faculty Publications

There is a growing consensus among ecologists that ecological facilitation comprises a historically overlooked but crucial suite of biotic interactions. Awareness of such positive interactions has recently led to substantial modifications in ecological theory. In this article we suggest how facilitation may be included in evolutionary theory. Natural selection based on competition provides a conceptually complete paradigm for speciation, but not for major evolutionary transitions-the emergence of new and more complex biological structures such as cells, organisms, and eusocial populations. We find that the successful theories developed to solve these specific problematic transitions show a consistent pattern: they focus on …


Naive Prey Versus Nonnative Predators: A Role For Behavior In Endangered Species Conservation, Stephanie A. Kraft May 2009

Naive Prey Versus Nonnative Predators: A Role For Behavior In Endangered Species Conservation, Stephanie A. Kraft

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Fish are one of the most imperiled groups of vertebrates worldwide. Threats to fish fall into one of four general categories: physical habitat loss or degradation, chemical pollution, overfishing, and nonnative species introductions. Nonnative predatory fish often have a devastating impact on native prey, especially with endemic fish, whose restricted distribution and often limited evolutionary history with predators make them particularly susceptible to nonnative predators. One reason nonnative fish are often so efficient predators is that the native fish do not recognize the predator as a threat. Although many studies have examined the role of predator odor recognition, no fish …


My Two Boots ... A Walk Through The Wetlands. An Annual Outing For 700 Middle School Students, Julie Cwikla, Mark Lasalle, Sybil Wilner May 2009

My Two Boots ... A Walk Through The Wetlands. An Annual Outing For 700 Middle School Students, Julie Cwikla, Mark Lasalle, Sybil Wilner

Faculty Publications

No abstract provided.


Seed Predation On Slickspot Peppergrass By The Owyhee Harvester Ant, Joshua P. White May 2009

Seed Predation On Slickspot Peppergrass By The Owyhee Harvester Ant, Joshua P. White

Boise State University Theses and Dissertations

  1. (1) Seed predation can significantly restrict the reproductive output and individual fitness of plants, particular those plants that are rare or endangered. In some cases the total seed loss can reach 100%. Owyhee harvester ants, Pogonomyrmex salinus, actively remove the fruits and seeds of slickspot peppergrass, Lepidium papilliferum, a rare mustard endemic to southwest Idaho.
  2. (2) Several experiments were conducted to quantify seed predation on L. papilliferum located within the foraging distance of P. salinus. Individuals exposed to harvester ants experienced a direct loss of fruits and seeds ( > 40%), whereas plants shielded from ants suffered almost …


The Effects Of Prenatal Exposure Of Valproic Acid On Cranial Nerve Nuclei: A Rat Model For An Autistic Phenotype, Shannon Pickup May 2009

The Effects Of Prenatal Exposure Of Valproic Acid On Cranial Nerve Nuclei: A Rat Model For An Autistic Phenotype, Shannon Pickup

Renée Crown University Honors Thesis Projects - All

Autistic spectrum disorder is a term referring to five pervasive developmental disorders characterized by impairment in social interaction, deficits in verbal and non-verbal communication and stereotyped repetitive behaviors and interests. The underlying brain injury that leads to autism is also unknown. The cause is also unknown but appears to be a combination of genetic and environmental factors. A study on prenatal thalidomide exposure found patients exposure on days 20-24 of gestation lead to a 1/3 rate of autism, a huge increase from the 1/150 rate of the general population. The thalidomide data suggests the initial injury leading to autism occurs …


Generation Of An Fsh Inducible Inh-[Alpha]-Flag-Gg-Icer I[Gamma] Ovarian Specific Gene Construct, Goce Bogdanoski May 2009

Generation Of An Fsh Inducible Inh-[Alpha]-Flag-Gg-Icer I[Gamma] Ovarian Specific Gene Construct, Goce Bogdanoski

Theses, Dissertations and Culminating Projects

Avian animal models have led to many essential discoveries in molecular biology and biochemistry, including the discovery of vitamins, the chemistry behind vision and the development of transgenic hens as natural bioreactors for pharmaceutically relevant proteins. Hyperovulation in domesticated hens is considered a highly desirable genetic trait, a feature that has been explored in multiple studies and remains the focus of many biotech companies. Unlocking the molecular mechanism that controls ovulation may provide a basis for development in new reproductive technologies.

Previous research done on rodents provided data and identified a single transcription factor, the Inducible cAMP Early Repressor (ICER), …


Endurance And Exercise Physiology In Urosaurus Ornatus: Sex And Morph Differences?, Elizabeth Christine Foulkes May 2009

Endurance And Exercise Physiology In Urosaurus Ornatus: Sex And Morph Differences?, Elizabeth Christine Foulkes

All-Inclusive List of Electronic Theses and Dissertations

Locomotory performance has been the focus of many ecological and evolutionary studies, and lizards have been a model system. While several studies have demonstrated interspecific differences in performance, few have examined intraspeciflc variation in performance and the suites of underlying physiological traits in tree lizards ( Uro.,·aurns ornatus) a species with alternative reproductive tactics that show variation in spatial use patterns. To assess the functional ecology of movement behaviors of male morphs and or females, I examined variation in exertion, plasma metabolites, plasma steroid hormones, and muscle fiber types in ornate tree lizards ( Urosaurus ornalus). In my study population, …


Evolutionary Analysis Of Host Proteins Cd4, Cxcr4 And Ccr5, And Hiv/Siv Gp12, Lana Bunning May 2009

Evolutionary Analysis Of Host Proteins Cd4, Cxcr4 And Ccr5, And Hiv/Siv Gp12, Lana Bunning

Biological Sciences

The acquired immune deficiency syndrome, AIDS, is a growing epidemic in the United States and the world. Since its discovery in 1981, the virus that causes AIDS, human immunodeficiency virus (HIV), has escalated. .Certain African ape (i.e., chimpanzees and gorillas) and monkey species are known to harbor forms of the virus termed SIV (simian immunodeficiency virus). Chimpanzees are the natural hosts of the SIV strains from which HIV-I evolved, but do not rapidly progress to AIDS, unlike their human relatives. In the wild, gorillas have been observed to harbor SIV, but this species' disease progression is currently unknown. As the …


Cognitive Inference And Resulting Behaviors In Response To Ambiguous Threat In The Coyote, Canis Latrans, Sarah Shawnee Dawson May 2009

Cognitive Inference And Resulting Behaviors In Response To Ambiguous Threat In The Coyote, Canis Latrans, Sarah Shawnee Dawson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

While antipredator strategies have been a focus of behavioral research for decades, scientists generally study the responses of prey toward overt, explicit threat. However, risk can also be significant when a threat is covert, such as when an ambush predator may be nearby or a secondary threat remains after a predator's departure. Little is known about the mechanism that prey use to assess risk in a predator's absence. Tests were conducted to determine the manner in which coyotes respond to these ambiguous threats. Specifically, I tested whether coyotes respond to prior anthropogenic activity that has occurred near their only food …


Effects Of Targeted Grazing And Prescribed Burning On Fire Behavior And Community Dynamics Of A Cheatgrass (Bromus Tectorum)-Dominated Landscape, Joel M. Diamond May 2009

Effects Of Targeted Grazing And Prescribed Burning On Fire Behavior And Community Dynamics Of A Cheatgrass (Bromus Tectorum)-Dominated Landscape, Joel M. Diamond

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Studies were conducted to determine the effectiveness of using targeted grazing and prescribed burning as tools to reduce fire hazards and cheatgrass (Bromus tectorum) dominance on rangelands in the northern Great Basin. A field study, with four grazing-burning treatments (graze and no-burn, graze and burn, no-graze and burn, and no-graze and no-burn), was conducted on a B. tectorum-dominated site near McDermitt, Nevada from 2005-2007. Cattle removed 80-90% of standing biomass in grazed plots in May 2005 and 2006 when B. tectorum was in the boot (phenological) stage. Grazed and ungrazed plots were burned in October 2005 and …


Characterization Of The Substrate Specificity And Mechanism Of Protein Arginine Methyltransferase 1, Whitney Lyn Wooderchak May 2009

Characterization Of The Substrate Specificity And Mechanism Of Protein Arginine Methyltransferase 1, Whitney Lyn Wooderchak

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Protein arginine methyltransferases (PRMTs) posttranslationally modify protein arginine residues. Type I PRMTs catalyze the formation of monomethylarginine (MMA) and asymmetric dimethylarginine (ADMA) via methyl group transfer from S-adenosyl methionine onto protein arginine residues. Type II PRMTs generate MMA and symmetric dimethylarginine. PRMT-methylation affects many biological processes. Although PRMTs are vital to normal development and function, PRMT-methylation is also linked to cardiovascular disease, stroke, multiple sclerosis, and cancer.

Thus far, nine human PRMT isoforms have been identified with orthologues present in yeast, plants, and fish. PRMT1 predominates, performing an estimated 85% of all protein arginine methylation in vivo. Yet, the substrate …


A Study On The Mechanisms Of Mercury Tolerance In The Cyanobacterium, Synechococcus Sp. Iu 625, Winder Bienvenido Perez May 2009

A Study On The Mechanisms Of Mercury Tolerance In The Cyanobacterium, Synechococcus Sp. Iu 625, Winder Bienvenido Perez

Theses, Dissertations and Culminating Projects

Synechococcus sp. IU 625 (Anacystis nidulans) is a freshwater unicellular cyanobacterium and an obligate photoautotroph that readily harbors plasmids. This organism has been used in many studies to assess the effect of heavy metal toxicity as an environmental pollutant. In one of the few studies for strain IU 625, Simon isolated 4.7- MDa and 37-MDa plasmids in 1978. The relationship between these plasmids and the 7.6-kb and 46.6-kb plasmids of strain PCC 7942 is unknown. Primers designed based on the sequence of 46.6-kb plasmid pANL of PCC 7942 exhibited positive priming with isolated plasmid DNA from Syn. …


Spermiogenesis And In Vitro Culture Of Spermatogenic Cysts In Drosophila Pseudoobscura, Monicah Njogu May 2009

Spermiogenesis And In Vitro Culture Of Spermatogenic Cysts In Drosophila Pseudoobscura, Monicah Njogu

Seton Hall University Dissertations and Theses (ETDs)

Spennatogenesis is a complex process that involves differentiation and morphological changes of diploid stem cells into highly specialized, haploid, motile germ cells. Many of the transformative processes involved in mammalian spermatogenesis are conserved in flies, and their study would be facilitated by the availability of a reliable in vitro culture system. Culture of Drosophila melanogaster spermatogenic cysts is limited in usefulness because of early degeneration of cysts, low yield of elongated spermatozoa, and rare occurrences of motile sperm. We have developed a culture system for studying fly spermatogenesis using isolated spermatogenic cysts from the testes of Drosophila pseudoobscura. This species …


Distribution And Site Selection Of Le Conte's And Crissal Thrashers In The Mojave Desert: A Multi-Model Approach, Dawn Marie Fletcher May 2009

Distribution And Site Selection Of Le Conte's And Crissal Thrashers In The Mojave Desert: A Multi-Model Approach, Dawn Marie Fletcher

UNLV Theses, Dissertations, Professional Papers, and Capstones

Information on the distribution and habitat requirements of a species are critical components to the development of meaningful conservation plans. Such knowledge, however, is particularly difficult to obtain for species that are elusive and occur at low densities, such as the Le Conte's ( Toxostoma lecontei ) and Crissal (Toxostoma crissale ) thrashers. In association with a regional conservation plan, I evaluated the distribution and habitat selection of these thrashers within Clark County, Nevada in the eastern Mojave Desert. I used a call-broadcast approach to sample 432 stratified random locations, detecting Le Conte's thrashers at 45 locations and Crissal …


Arid Climate Decomposition And Decay: A Taphonomic Study Using Swine, James William Munkres May 2009

Arid Climate Decomposition And Decay: A Taphonomic Study Using Swine, James William Munkres

UNLV Theses, Dissertations, Professional Papers, and Capstones

The present project analyzes the taphonomic processes and variables involved in the decomposition and desiccation of animal remains in an arid/hyper-arid environment. The study and the derived data will assist in determining postmortem intervals for remains in modern contexts, inform judgments made regarding mortuary habits and techniques in archaeological contexts, and will improve our knowledge regarding taphonomic processes. Manner of deposition, the depositional surface/medium and arid-climate specific variables (temperature, water, insect activity, weathering, pH levels, and soil characteristics) were examined in this study. Reported observations are limited to the first ten months following death from early December through early October …


Stress Responses To Salinity In A Native Fresh Water Snake (Nerodia Rhombifer), Joana A. Cordoba May 2009

Stress Responses To Salinity In A Native Fresh Water Snake (Nerodia Rhombifer), Joana A. Cordoba

Theses and Dissertations - UTB/UTPA

Salinity stress at 0 ppt, 9 ppt, 18 ppt, and 27 ppt was investigated in Nerodia rhombifer, a fresh water snake. The purpose of this study was to establish if exposure to salinity could elicit a hormonal response in the form of corticosterone. Salinity treatment 27 ppt was lethal for 50% of the snakes. Factors such as population and gender differences were not significant, p=0.748 and p=0.135, respectively. Exposure to the different salinities did not significantly affect the overall mass of the animal, p=0.951. A significant increase in circulating corticosterone was noted in salinity treatments 0 ppt and 18 ppt, …


Predator And Abiotic Effects On Hatching Phenotype And Survival Of Arboreal Frog Eggs With Implications For Phytoplankton, Jessica Hite May 2009

Predator And Abiotic Effects On Hatching Phenotype And Survival Of Arboreal Frog Eggs With Implications For Phytoplankton, Jessica Hite

Theses and Dissertations

Historically studies have focused on either the terrestrial or aquatic environments independently. However, these systems are inherently linked through numerous pathways including organisms with complex life cycles. Both abiotic factors and predators of these organisms can influence connections by changing the number of prey moving across habitat boundaries and by changing the phenotype of prey. When the focal organisms are primary consumers, these effects may have important implications for ecosystem processes. My study investigated how terrestrial predators and abiotic factors affect the number and phenotype of herbivorous tadpole inputs into a tropical forest pond. I found that predators and abiotic …


Transcriptomic Analysis Of The Entomopathogenic Nematode Heterorhabditis Bacteriophora Tto1, Byron J. Adams, Xiaodong Bai, Todd A. Ciche, Sandra Clifton, Randy Gaugler, Parwinder S. Grewal, Saskia A. Hogenhout, John Spieth, Paul W. Sternberg, Richard K. Wilson Apr 2009

Transcriptomic Analysis Of The Entomopathogenic Nematode Heterorhabditis Bacteriophora Tto1, Byron J. Adams, Xiaodong Bai, Todd A. Ciche, Sandra Clifton, Randy Gaugler, Parwinder S. Grewal, Saskia A. Hogenhout, John Spieth, Paul W. Sternberg, Richard K. Wilson

Faculty Publications

Background: The entomopathogenic nematode Heterorhabditis bacteriophora and its symbiotic bacterium, Photorhabdus luminescens, are important biological control agents of insect pests. This nematode-bacterium-insect association represents an emerging tripartite model for research on mutualistic and parasitic symbioses. Elucidation of mechanisms underlying these biological processes may serve as a foundation for improving the biological control potential of the nematode-bacterium complex. This large-scale expressed sequence tag (EST) analysis effort enables gene discovery and development of microsatellite markers. These ESTs will also aid in the annotation of the upcoming complete genome sequence of H. bacteriophora. Results: A total of 31,485 high quality ESTs were generated …


Analyzing The Interconnectedness Between Space, Place, And Human Interaction With The Natural Environment: "Ecological Reawakening: Organic Dna And Evolution", Sarah Moos Apr 2009

Analyzing The Interconnectedness Between Space, Place, And Human Interaction With The Natural Environment: "Ecological Reawakening: Organic Dna And Evolution", Sarah Moos

Scripps Senior Theses

I have organized this paper into four chapters: "The Environmental Situation," "Space and Place," "Art and the Natural Environment," and "Creating Work of My Own." Chapter 1 explains human beings' intrinsic interconnection to the natural environment, outlining why humans should be concerned about the current degraded state of the natural world. Chapter 2 discusses the concepts of space and place. It analyzes how human beings interact with and experience spaces, developing their sense of place - within physical, theoretical, and spiritual realms. It finally illustrates the importance that spaces and places have in humans' lives. Chapter 3 describes the Land …


An Analysis Of The Environmental And Hormonal Effects On The Growth And Development Of The Moss Ceratodon Purpureus, Megan Knight Apr 2009

An Analysis Of The Environmental And Hormonal Effects On The Growth And Development Of The Moss Ceratodon Purpureus, Megan Knight

Undergraduate Honors Thesis Collection

Ceratodon has not been documented in scientific literature as thoroughly as other species of moss such as Funaria or Tortula. Commonly known as fire moss or purple horned moss, Ceratodon is often reddish or yellow-brown and the spore capsules are usually purple (Crum, 1983). A picture of the species growing in its natural habitat is shown in Figure 4. Ceratodon often grows in tufts and is considered a weed, often thriving in polluted or disturbed areas and frequently invading after a fire (Crum 1983). Ceratodon belongs to the class Bryopsida, which also contains the previously mentioned Funaria and Tortula species. …


Lead Bullet Fragments In Venison From Rifle-Killed Deer: Potential For Human Dietary Exposure, W. Grainger Hunt, Richard T. Watson, J. Lindsay Oaks, Chris N. Parish, Kurt K. Burnham, Russell L. Tucker, James R. Belthoff, Garret Hart Apr 2009

Lead Bullet Fragments In Venison From Rifle-Killed Deer: Potential For Human Dietary Exposure, W. Grainger Hunt, Richard T. Watson, J. Lindsay Oaks, Chris N. Parish, Kurt K. Burnham, Russell L. Tucker, James R. Belthoff, Garret Hart

Biology Faculty Publications and Presentations

Human consumers of wildlife killed with lead ammunition may be exposed to health risks associated with lead ingestion. This hypothesis is based on published studies showing elevated blood lead concentrations in subsistence hunter populations, retention of ammunition residues in the tissues of hunter-killed animals, and systemic, cognitive, and behavioral disorders associated with human lead body burdens once considered safe. Our objective was to determine the incidence and bioavailability of lead bullet fragments in hunter-killed venison, a widely-eaten food among hunters and their families. We radiographed 30 eviscerated carcasses of White-tailed Deer (Odocoileus virginianus) shot by hunters with standard …


Developmental Changes In Zebrafish Embryos Exposed To Bisphenol A Leeched From Commonly Used Plastics, David L. Ortiz Apr 2009

Developmental Changes In Zebrafish Embryos Exposed To Bisphenol A Leeched From Commonly Used Plastics, David L. Ortiz

Senior Honors Theses

Bisphenol A, an estrogen mimicker, is found in the commonly used plastic, polycarbonate. Zebrafish embryos were raised in water that had been heated in polycarbonate water bottles by either microwaving for 5 minutes, or boiling for one hour. Near total mortality was seen in 7 days for the embryos growing in bottle-microwaved water, and 9 days for those raised in bottle-boiled water. Zebrafish embryos were also grown in the following known concentrations of BPA: 2mg/l, 14mg/l, 16mg/l, 50mg/l, 135mg/l, and 235mg/l. A stepwise relationship between concentration of BPA and embryo lifespan was seen, and the lowest observed adverse effect level …


The Presence Of Amphibian Ranavirus In Virginia Warm Water Fish Hatchery Ponds, Elizabeth Nelson Apr 2009

The Presence Of Amphibian Ranavirus In Virginia Warm Water Fish Hatchery Ponds, Elizabeth Nelson

Theses and Dissertations

Amphibian declines have been occurring world wide over the past several decades. Infectious disease and environmental changes have been implicated as the causative agents in these declines. Fish stocking from hatcheries provides a unique opportunity for organisms, including infectious diseases, to travel over long distances. Ranavirus was previously found in two ponds at Harrison Lake National Fish Hatchery in Charles City County, Virginia. Therefore, the primary objective of this study was to determine if ranavirus is present in tadpoles from four warm water fish hatcheries in Virginia. A secondary objective of this study was to determine if there are relationships …


From In-Vitro To In-Vivo: Corporate Development And Efficacy Of A Topical Hair Growth Agent Derived From Natural Extracts, Kelly Michael Glynn Apr 2009

From In-Vitro To In-Vivo: Corporate Development And Efficacy Of A Topical Hair Growth Agent Derived From Natural Extracts, Kelly Michael Glynn

Masters Theses

Androgenetic alopecia (male pattern baldness) affects up to 50% of the world’s population, propelling the development for a possible treatment. The hair follicle is influenced by several genetic and physiologic factors, which, when gone awry, lead to androgenetic alopecia. Vascular endothelial and keratinocyte growth factors are believed to be promoters of hair growth, as is inhibition of the proteasome complex. The cytokine IL-1α is also known to regulate follicle dynamics. The research objective described herein was an attempt to develop a botanical blend, which could mediate the above biomarkers, be successfully incorporated into a safe topical product and be evaluated …


Molecular Systematics Of Spiny Pocket Mice (Subfamily Heteromyinae) Inferred From Mitochondrial And Nuclear Sequence Data, Melina Crystal Williamson Apr 2009

Molecular Systematics Of Spiny Pocket Mice (Subfamily Heteromyinae) Inferred From Mitochondrial And Nuclear Sequence Data, Melina Crystal Williamson

Theses and Dissertations

This study aims to determine species-level relationships within the genus Heteromys, as well as generic-level relationships among members of the subfamily Heteromyinae using a phylogenetic framework. Molecular sequence data were generated from two mitochondrial genes (cytochrome b and cytochrome oxidase I) and three nuclear gene segments (β-fibrinogen, engrailed protein II, and myosin heavy chain II), and analyzed under maximum parsimony, maximum likelihood, and Bayesian optimality criteria to infer relationships. Chapter 1 focuses on the phylogenetic and taxonomic implications for Heteromys from the analyses of sequence data. Phylogenies also provided a framework for delimiting species boundaries within the wide-ranging Heteromys desmarestianus …