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Novel Phytol-Derived Immunostimulants (Phis-01) For Enhancement Of Vaccine Efficacy: A Comparative Study, Youssef Aachoui Aug 2011

Novel Phytol-Derived Immunostimulants (Phis-01) For Enhancement Of Vaccine Efficacy: A Comparative Study, Youssef Aachoui

All-Inclusive List of Electronic Theses and Dissertations

Adjuvants are used widely in vaccine formulations. However for humans, choices are very limited. Since they are selected empirically, it is not expected that any two adjuvants would influence immune mechanisms the same way. However they all influence host microenvironment, antigen presentation, and retention of immunological memory. This study focuses on new terpenoid adjuvants based on phytol derivatives. We previously observed that phytol and one of its derivatives PHIS-01 (a phytol-based immunostimulant, phytanol) are excellent adjuvants. To gain an understanding of the structural features important for adjuvanticity, we further studied compounds derived from a diterpene Phytol. We designed two new …

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Characterization Of The Serologic Responses To Plasmodium Vivax Dbpii Variants Among Inhabitants Of Pursat Province, Cambodia, Samantha Jones Barnes Jul 2011

Characterization Of The Serologic Responses To Plasmodium Vivax Dbpii Variants Among Inhabitants Of Pursat Province, Cambodia, Samantha Jones Barnes

USF Tampa Graduate Theses and Dissertations

The Plasmodium vivax Duffy Binding Protein (DBP) is the ligand in the major pathway for P. vivax invasion of human reticulocytes, making it an appealing vaccine candidate. Region II of DBP (DBP-RII) is the minimal portion of the ligand that mediates recognition of the Duffy Antigen Receptor for Chemokines (DARC receptor) on the reticulocyte surface and constitutes the primary vaccine target. Analysis of natural variation in the coding sequences of DBP-RII revealed signature evidence for selective pressure driving variation in the residues of the putative receptor-binding site. We hypothesize that anti-DBP immunity in P. vivax infections is strain-specific and hindered …

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Nursing Students’ Attitudes Toward People With Mental Illness: Do They Change After Instruction And Clinical Exposure?, Rachel Morrison Jul 2011

Nursing Students’ Attitudes Toward People With Mental Illness: Do They Change After Instruction And Clinical Exposure?, Rachel Morrison

Honors Thesis and Capstone Projects

People with mental illness are among the most stigmatized groups of patients in the healthcare setting (Putnam, 2008). Nurses comprise roughly 15.3 percent of the healthcare team (U.S. Bureau of Labor Statistics, 2010) and have frequent direct interactions with patients. As one of the larger groups of healthcare providers, nurses can potentially influence this stigma, either by contributing to the prevalent negative attitudes, or by confronting expressions of stigma. A requirement for licensure is to take a course in Mental Health. One of the goals of this course is to decrease stigma toward people with mental illness (American Association of …

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Transylvania Medical Alumni Who Served In The Union And Confederate Armies, Charles T. Ambrose Jul 2011

Transylvania Medical Alumni Who Served In The Union And Confederate Armies, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

No abstract provided.

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Ada News - 05/16/2011, American Dental Association, Publishing Division May 2011

Ada News - 05/16/2011, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

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Inflammatory Gene Variants In The Tsimane, An Indigenous Bolivian Population With A High Infectious Load, Sarinnapha Vasunilashorn, Caleb E. Finch, Eileen M. Crimmins, Suvi A. Vikman, Jonathan Stieglitz, Michael Gurven, Hillard Kaplan, Hooman Allayee May 2011

Inflammatory Gene Variants In The Tsimane, An Indigenous Bolivian Population With A High Infectious Load, Sarinnapha Vasunilashorn, Caleb E. Finch, Eileen M. Crimmins, Suvi A. Vikman, Jonathan Stieglitz, Michael Gurven, Hillard Kaplan, Hooman Allayee

ESI Publications

The Tsimane of lowland Bolivia are an indigenous forager-farmer population living under conditions resembling pre-industrial European populations, with high infectious morbidity, high infection and inflammation, and shortened life expectancy. Analysis of 917 persons ages 5 to 60+ showed that allele frequencies of 9 SNPs examined in the apolipoprotein E (apoE), C-reactive protein (CRP), and interleukin-6 (IL-6) genes differed from some European, African, and north Asian-derived populations. The apoE2 allele was absent, whereas four SNPs related to CRP and IL-6 were monomorphic: CRP (rs1800947, rs3093061, and rs3093062) and IL-6 (rs1800795). No significant differences in apoE, CRP, and IL-6 variants across age …

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Crusader, May 6, 2011, College Of The Holy Cross May 2011

Crusader, May 6, 2011, College Of The Holy Cross

Student Newspapers

The student newspaper for the College of the Holy Cross in Worcester, Massachusetts. Articles include coverage of campus events and issues, sports, editorials and special features.

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Archaeoparasitology Of Chaco Canyon, Rachel Paseka May 2011

Archaeoparasitology Of Chaco Canyon, Rachel Paseka

Department of Environmental Studies: Undergraduate Student Theses

Ancient cultures of the Colorado Plateau have been a focus of archaeoparasitology since its inception, and a vast parasitological history is recorded in coprolites preserved in this arid region. The inhabitants of Chaco Canyon dominated Ancestral Puebloan culture between 1050 and 1120 AD and were responsible for the construction of great towns, road systems, and early agriculture. Analysis of the parasites preserved in fecal remains contributes to an increased knowledge of ancient Chacoan health and culture. Nineteen coprolites from four sites in Chaco Canyon were rehydrated and analyzed microscopically for parasite remains. Rhabditiform and filariform nematode larvae were found from …

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The Knowledge, Attitudes, And Behaviors Of Gay, Lesbian, Bisexual And Transgender University Of South Florida (Usf) Students Concerning Human Papillomavirus (Hpv) And The Hpv Vaccine, Andrea E. Larson May 2011

The Knowledge, Attitudes, And Behaviors Of Gay, Lesbian, Bisexual And Transgender University Of South Florida (Usf) Students Concerning Human Papillomavirus (Hpv) And The Hpv Vaccine, Andrea E. Larson

Honors Thesis and Capstone Projects

Human papillomavirus (HPV) is one of the most common sexually transmitted diseases and can cause several types of cancer, including cervical and anal cancer. The lesbian, gay, bisexual, and transgender (LGBT) population is an often overlooked subgroup at risk for HPV. The purpose of this research was to describe LGBT college students‟ knowledge, attitudes, and behaviors pertaining to HPV and the HPV vaccine. An online survey consisting of 54 items was created and sent to members of an organization consisting primarily of LGBT students at the University of South Florida. A total of 155 students completed the survey. Several major …

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The Rhetorics Of Constructing Hiv/Aids In The United States And China: A Comparative Analysis Of Two Online Discussion Forums, Jingwen Zhang May 2011

The Rhetorics Of Constructing Hiv/Aids In The United States And China: A Comparative Analysis Of Two Online Discussion Forums, Jingwen Zhang

All Theses

This thesis focuses on the cross-cultural comparison of the public rhetorics that construct HIV/AIDS in two online discussion forums from the United States and China. Social constructions of HIV/AIDS have previously been explored in specific countries and cultures; however, comparative studies have rarely been conducted, especially by applying rhetorical cultural analysis focusing on online discourses. Responding to these gaps in research, this study combines two underexplored dimensions -- comparative rhetorical analysis and online discourse -- to show how online communications, metaphors, and topoi identified in discussion forum posts reveal and construct the idea of HIV/AIDS in the public sphere for …

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2011 - The Sixteenth Annual Symposium Of Student Scholars Apr 2011

2011 - The Sixteenth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Sixteenth Annual Symposium of Student Scholars, held on April 26, 2011. Includes abstracts from the presentations and posters.

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Ada News - 04/04/2011, American Dental Association, Publishing Division Apr 2011

Ada News - 04/04/2011, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

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Anti-Malarial Activity Exhibited By Florida Mangrove Endophytes, Jacqueline Lee Salm Apr 2011

Anti-Malarial Activity Exhibited By Florida Mangrove Endophytes, Jacqueline Lee Salm

Honors Thesis and Capstone Projects

Many organisms around the world including plants, marine organisms, and microbes release chemicals used for things such as pigment or defense against other organisms. These chemicals are known as secondary metabolites and have been found to exhibit promising activity against many infectious diseases and cancer. Natural products chemistry is the study of these secondary metabolites with one of the purposes to discover new small organic molecules for potential pharmaceutical use in the future. With parasitic diseases, such as malaria, prominent throughout the poorest regions of the world, there are great opportunities for discovering anti-malarial drugs from natural products. Approximately 250 …

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Secondary Metabolites From Antarctic Marine Invertebrates And Their Potential As Drug Leads, Samantha Landolfa Apr 2011

Secondary Metabolites From Antarctic Marine Invertebrates And Their Potential As Drug Leads, Samantha Landolfa

Honors Thesis and Capstone Projects

The Antarctic region is of particular interest to natural products chemists because it remains relatively unexplored and possesses a wealth of unique biodiversity. Organisms that thrive in this region must produce different chemical defenses to survive in the harsh polar environment, making their secondary metabolites original and potentially useful as drugs for human disease. These compounds often have very complex structures, making their syntheses difficult and impractical. With this knowledge, five Antarctic marine invertebrates were extracted in search of their secondary metabolites. The chemical isolation studies were performed by macroorganism solvent extraction followed by chromatographic separation and purification of metabolites …

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Transylvania Medical Alumni Served Both Sides During The Civil War, Charles T. Ambrose Apr 2011

Transylvania Medical Alumni Served Both Sides During The Civil War, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

No abstract provided.

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Father Death And Adult Success Among The Tsimane: Implications For Marriage And Divorce, Jeffrey Winking, Michael Gurven, Hillard Kaplan Mar 2011

Father Death And Adult Success Among The Tsimane: Implications For Marriage And Divorce, Jeffrey Winking, Michael Gurven, Hillard Kaplan

ESI Publications

Human fathers are heavily involved in the rearing of children around the world. While there is great cross-cultural variation, the father is a recognizable role in all populations. This deviates from the standard mammalian pattern of little paternal investment. A logical explanation offered early by evolutionary theorists is that human fathers evolved the capacity for paternal concern because human children are remarkably needy and impose a great encumbrance on the mother (Lancaster & Lancaster, 1983; Lovejoy, 1981). Thus, fathers have greater opportunity to enhance the wellbeing of child and mother, as there is a deeper well of need to fill. …

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Culture, Dissent, And The State: The Example Of Commonwealth African Marriage Law, Johanna E. Bond Jan 2011

Culture, Dissent, And The State: The Example Of Commonwealth African Marriage Law, Johanna E. Bond

Scholarly Articles

This is an explosive time for those seeking to define the meaning and parameters of marriage. The subject has generated heated debate worldwide. In June 2010, the European Court of Human Rights declined to extend marriage rights to a gay Austrian couple, but the Court carefully laid the foundation for the recognition of such rights when a European consensus on the issue emerges. In July 2010, Argentina extended to same-sex couples the right to marry, joining nine other countries that legally recognize same-sex couples' right to marry. In August 2010, a United States district judge struck down a California ban …

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Visual Rhetoric And The Promotion Of Scientific Ideas: The Strange Case Of The Prion, Carol Reeves Jan 2011

Visual Rhetoric And The Promotion Of Scientific Ideas: The Strange Case Of The Prion, Carol Reeves

Scholarship and Professional Work - LAS

In the field that investigates infectious brain diseases such as mad cow disease, the verbal and visual packaging of scientific visuals associated with identifying the agent, prion, its processes, and structure served the community ritual of establishing belief in a highly unorthodox phenomenon. Visual promotion fed into cultural expectations of single agents and simple processes, even though the actual agency and disease process have proven highly complex and perhaps unknowable.

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Modeling And Surveillance Of Pandemic Influenza Outbreaks, Diana Prieto Jan 2011

Modeling And Surveillance Of Pandemic Influenza Outbreaks, Diana Prieto

USF Tampa Graduate Theses and Dissertations

Pandemic outbreaks are unpredictable as to their virus strain, transmissibility, and impact on our quality of life. Hence, the decision support models for mitigation of pandemic outbreaks must be user-friendly and operational, and also incorporate valid estimates of disease transmissibility and severity. This dissertation research is aimed at 1) reviewing the existing pandemic simulation models to identify their implementation gaps with regard to usability and operability, and suggesting research remedies, 2) increasing operability of simulation models by calibrating them via an epidemiological model that estimates infection probabilities using viral shedding profiles of concurrent pandemic and seasonal influenza, and 3) developing …

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Ada Code Of Ethics (January 2011), American Dental Association Jan 2011

Ada Code Of Ethics (January 2011), American Dental Association

Code of Ethics

The ADA Code of Ethics has three main components: The Principles of Ethics, the Code of Professional Conduct and the Advisory Opinions. Contents may also include: Amendment to ADA Principles of Ethics and Code of Professional Conduct and Insert for the ADA Principles of Ethics and Code of Professional Conduct. The most current issue is available on the ADA’s website.

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Starved: Food Deserts In The Mississippi Delta, Novelette L. Brown Jan 2011

Starved: Food Deserts In The Mississippi Delta, Novelette L. Brown

Electronic Theses and Dissertations

This thesis examines the impact of food deserts on obesity, and builds a case for additional research on rural food deserts independent from urban ones. The Mississippi Delta consistently presents the highest obesity rates within the state, yet both the third unhealthiest county (Quitman) and the healthiest (DeSoto) are located in that region. One of the reasons there is such a large discrepancy between the health rankings of DeSoto and Quitman counties is that DeSoto is contained within the Greater Memphis Metropolitan Area, but Quitman is entirely rural. Previous research has focused on the prevalence of urban food deserts and …

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Women War Survivors Of The 1989-2003 Conflict In Liberia: The Impact Of Sexual And Gender-Based Violence, Helen Liebling-Kalifani, Victoria Mwaka, Ruth Ojiambo-Ochieng, Juliet Were-Oguttu, Eugene Kinyanda, Deddeh Kwekwe, Lindora Howard, Cecilia Danuweli Jan 2011

Women War Survivors Of The 1989-2003 Conflict In Liberia: The Impact Of Sexual And Gender-Based Violence, Helen Liebling-Kalifani, Victoria Mwaka, Ruth Ojiambo-Ochieng, Juliet Were-Oguttu, Eugene Kinyanda, Deddeh Kwekwe, Lindora Howard, Cecilia Danuweli

Journal of International Women's Studies

This article presents a summary of the qualitative data from research carried out in post-conflict Liberia by Isis-WICCE, a women’s international non-government organisation, in conjunction with the Ministry of Gender and Development of Liberia and Women in Peace-building Network, WIPNET. Analysis of research findings detail women’s experiences of conflict and the serious effects of sexual violence and torture on their physical and psychological health. The paper also describes the omission of women from justice and rehabilitation processes. In support of women participants’ views, the author’s recommend that funding is urgently required for the provision of holistic and sustainable, gender-sensitive services. …

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Risk Factors For Homelessness And Sex Trade Among Incarcerated Women: A Structural Equation Model, Seijeoung Kim, Timothy P. Johnson, Samir Goswami, Michael Puisis Jan 2011

Risk Factors For Homelessness And Sex Trade Among Incarcerated Women: A Structural Equation Model, Seijeoung Kim, Timothy P. Johnson, Samir Goswami, Michael Puisis

Journal of International Women's Studies

Incarcerated women are among the most vulnerable and perhaps the least studied populations in the US. Significant proportions of female inmates are substance users, and many living in unstable housing conditions or being homeless. Female inmates are often at high risk of engaging in sex exchange for drugs or housing needs. While a disproportionate number of incarcerated women have experienced childhood household adversities and maltreatments, the effects of these childhood experiences on psychosocial and behavioral outcomes of this population in later life. We apply a life course perspective to examine these pathways in a sample of incarcerated women in Cook …

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Exploiting Borders: The Political Economy Of Local Backlash Against Undocumented Immigrants, Jamie Longazel, Benjamin Fleury-Steiner Jan 2011

Exploiting Borders: The Political Economy Of Local Backlash Against Undocumented Immigrants, Jamie Longazel, Benjamin Fleury-Steiner

Sociology, Anthropology, and Social Work Faculty Publications

Four years prior to Arizona's passage of one of the most far-reaching pieces of anti-Latino immigrant legislation signed into law in decades,3 demands to "seal off the border"4 were being made thousands of miles from the U.S.-Mexico divide. In 2006, Hazleton, Pennsylvania, passed equally harsh legislation aimed at keeping undocumented immigrants out of their community. During this time, commentators described the local backlash in Hazleton and other small cities across the United States as akin to "the opening of a deep and profound fissure in the American landscape" 5 wherein "all immigration politics is local." 6 Yet, as the so-called …

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A Nutty Approach To Disease Prevention, Amin Esfahani Jan 2011

A Nutty Approach To Disease Prevention, Amin Esfahani

Quill & Scope

Tree nuts are healthy foods with a favourable macro- and micronutrient profile. They are low in sat-urated fats and high in mono- and polyunsaturated fatty acids. They are also good sources of vegeta-ble protein, fiber, phytosterols, polyphenols, vitamins and minerals. Because of this healthy nutrient profile, it has been postulated that tree nuts may play a significant role in health maintenance and disease prevention. The purpose of this paper is 1) to provide a brief overview of the current scien-tific evidence on the role of tree nuts in prevention and management of diabetes and heart disease and 2) to outline …

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Neighborhood Context As A Predictor Of Nursing Home Placement Among Older Adults, David Russell Buys Jan 2011

Neighborhood Context As A Predictor Of Nursing Home Placement Among Older Adults, David Russell Buys

All ETDs from UAB

Persons who are aging face an increased risk of adverse health events and decreased levels of personal competencies, potentially inhibiting their ability to age in place. Sometimes, nursing home placement (NHP) may be imperative, especially if persons experience environmental docility-- an incongruence of their physical capacity with their environment. This study links the neighborhood disadvantage literature with Lawton's environmental press and environmental docility theories to examine how the environment interacts with individual level variables to impact likelihood of NHP. Findings suggest that there is not a direct link between living in a disadvantaged context and likelihood of NHP, but that …

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Disease, Medicine And Health, Diego Armus, A. López Denis Jan 2011

Disease, Medicine And Health, Diego Armus, A. López Denis

History Faculty Works

This article focuses on three overlapping trends in the historical study of human responses to illness, labeled as “new history of medicine, history of public health, and sociocultural history of disease.” The topics range from colonial epidemiology and pharmacopoeia to twentieth-century public health institutions and urban hygiene. But a consistent focus on the social, cultural, and symbolic components of diseases and cures unifies this historiography and distinguishes it from the narrower scope of the long-established field of the history of medicine.

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The Great Influenza Of 1918 And The Alabama Debacle, Maya J. Orr Jan 2011

The Great Influenza Of 1918 And The Alabama Debacle, Maya J. Orr

Vulcan Historical Review

pp. 70-96

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Adapting Health-Risk Communication To The Specific Cultural Contexts Of Diverse Populations : An Assessment Of Malaria-Treatment Programs In Liberia, Nathaniel Galarea Gbessagee Jan 2011

Adapting Health-Risk Communication To The Specific Cultural Contexts Of Diverse Populations : An Assessment Of Malaria-Treatment Programs In Liberia, Nathaniel Galarea Gbessagee

Dissertations, Master's Theses and Master's Reports - Open

Drawing on theories of technical communication, rhetoric, literacy, language and culture, and medical anthropology, this dissertation explores how local culture and traditions can be incorporated into health-risk-communication-program design and implementation, including the design and dissemination of health-risk messages. In a modern world with increasing global economic partnerships, mounting health and environmental risks, and cross-cultural collaborations, those who interact with people of different cultures have “a moral obligation to take those cultures seriously, including their social organization and values” (Hahn and Inhorn 10). Paradoxically, at the same time as we must carefully adapt health, safety, and environmental-risk messages to diverse cultures …

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The Life And Times Of A Kansas Horse And Buggy Doctor And His Recollections On The Care Of Children, Robert D. Schremmer Md, Jane F. Knapp Md Jan 2011

The Life And Times Of A Kansas Horse And Buggy Doctor And His Recollections On The Care Of Children, Robert D. Schremmer Md, Jane F. Knapp Md

Posters

Describes the career of Arthur Emmanuel Hertzler, MD, 1870-1946, who practiced in Halstead, Kansas.

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