Systems Engineering Commons^™

Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence

Theses and Dissertations

Combining vibrating mesh nebulizers with additional new technologies leads to substantial improvements in pharmaceutical aerosol delivery to the lungs across therapeutic administration methods. In this dissertation, streamlined components, aerosol administration synchronization, and/or Excipient Enhanced Growth (EEG) technologies were utilized to develop and test several novel devices and aerosol delivery systems. The first focus of this work was to improve the poor delivery efficiency, e.g., 3.6% of nominal dose (Dugernier et al. 2017), of aerosolized medication administration to adult human subjects concurrent with high flow nasal cannula (HFNC) therapy, a form of continuous-flow non-invasive ventilation (NIV). The developed Low-Volume Mixer-Heater (LVMH) …

Size And Cost Reduction Of The Antenna 3000, Mario Mignott, Austin Deaver, Josh Madaris

Senior Design Project For Engineers

For our senior design project, we have partnered with Compass Technology Group to improve its Antenna 3000 manufacturing process. The Antenna we are working on is not actually called this, but due to NDA regulations, we will disguise it as the Antenna 3000. This will include finding a way to minimize material costs and labor hours involved to assemble this product together. Our minimum success criteria will be to reduce both the manufacturing time and materials' cost by 20%. Our primary approach to solving this problem will be to implement Lean Six Sigma practices such as the DMAIC principle.

Using …

Development Of A Deformation-Based Structural Health System With Contactless Sensors And Machine Learning For Health Characterization And Failure Prediction, Juan Camilo Avendano Arbelaez

Theses and Dissertations

This dissertation presents the design and development of a structural health monitoring (SHM) system specifically tailored for transportation infrastructure components, such as bridges. The proposed system collects data by using contactless sensors and performs health characterization and failure prediction. It is capable of simulating multiple load conditions on structures, identifying possible failure points, and detecting and predicting failure scenarios. Both hardware and software implementations of a model of a bridge were performed as a pilot project in order to validate the proposed system. Computer simulation in ANSYS and the application of gradient boosting neural networks were performed to produce a …

Continuous Integration/Continuous Delivery Pipeline For Air Force Distributed Common Ground System (Af Dcgs), Carolyn W. Fuller

Theses and Dissertations

AF DCGS has a recognized need to improve speed of delivery for modification and sustainment of the weapon system. Given that the program office implemented a Continuous Integration/Continuous Delivery (CI/CD) process for the sole purpose of delivering capability to the field faster, there is a need to measure and report the pipeline throughput. This research conducts an independent evaluation of the newly implemented pipeline within AF DCGS’s existing integration and test laboratories. Actual project data from the agile development work environments is studied and hypothesis tests are conducted to substantiate that the CI/CD pipeline improved the speed of delivery. The …

An Investigation On The Effectiveness Of A Problem Structuring Method In A Group Decision-Making Process, Ying Thaviphoke

Engineering Management & Systems Engineering Theses & Dissertations

There is no shortage of methods to address messy problems. A messy problem is a system of problems with multiple stakeholders who may hold different views of what is feasible or desirable. Decision-makers in a messy problem are prone to committing an error – especially the Type III error. One of the ways to mitigate the chance of committing the error in a messy problem is to reach a group consensus. Problem Structuring Methods (PSM) are the collections of participatory modeling methods that aim to tackle a messy problem. Despite the positive reports, literature indicates some challenges and criticisms of …

A Parametric Evaluation Of Iot Applications To Freight Transportation Using Model-Based Systems Engineering, Paul George Crawford

Theses and Dissertations

Industrial Internet of Things or IIoT consists of computing and communication at the operational edge of a value chain. Applications span manufacturing, energy, and transportation, among others. In the transportation context, IIoT translates to connected vehicle architecture and ITS applications. Current trends in communication allow more applications and devices to contribute to functions traditionally allocated to transportation ITS infrastructure. This poses challenges to design engineers to prototype emerging technologies in the existing transportation context and reduce integration, validation, and time to market. Model-based systems engineering is crucial step for IIoT deployment since it allows for a feature-rich digital representation of …

Using Interacting Multiple Model Filters To Indicate Program Risk, Amy Sunshine Smith-Carroll

Engineering Management & Systems Engineering Theses & Dissertations

Technology development has increased exponentially. Program managers are pushed to accelerate development. There are many resources available to program managers that enable acceleration, such as: additional resources in the form of funding, people and technology. There are also negative impacts to acceleration, such as: inclusion, inexperience program managers, and communication. This research seeks to identify the limit to which a program or project can be accelerated before the program manager begins to accept an unacceptable amount of pre-determined risk.

This research will utilize estimation algorithms used by sensor systems to estimate the current and future state of objects in space. …

Sports Analytics: Putting The Fun Back Into Analytics, Walt Degrange

Operations Management Presentations

With the recent success of sports teams heavily using analytics (Dodgers, Patriots, Capitals, Warriors, Leicester City F.C.), does this mean that analytics has gained a foothold in the sports world? I use a k-means clustering model to determine if performance since 2015 in the four major US sports can support this question. And is there a career path that a high school student can use to become a sports analytics professional? This presentation attempts to answer that question by exploring all the areas of the application of analytics in sports. The final point the brief makes is that by using …

Macroeconomic Aspects Of Maintenance Optimization Of Critical Infrastructures, S. A. Timashev, A. V. Bushinskaya

Engineering Management & Systems Engineering Faculty Publications

The main goal of maintenance is prevention, timely detection and elimination of failures and damage. From the point of view of critical infrastructures (CIs), the main purpose of their maintenance is to increase the safety of CIs and / or to ensure life safety. CIs should be optimal in terms of their purpose, cost, as a source of income and profit at all stages of their life cycle, and also acceptable in terms of possible loss of human lives or injuries. The paper considers the assessment of necessary optimal investments in the maintenance (time interval between subsequent maintenance), to increase …

Black-Swan Type Catastrophes And Antifragility/Supra-Resilience Of Urban Socio-Technical Infrastructures, S. A, Timashev

Engineering Management & Systems Engineering Faculty Publications

This paper may be one of the first attempts dealing with the problem of creating, providing and maintaining antifragility of systems of interdependent urban critical infrastructures (CI) in the wake of black-swan type technological, ecological, economic or social catastrophes occurring in a municipality. A synonym is offered to describe antifragility from a positive psychology perspective, formulating the problem as the supraresilience problem. A brief description is given of the developed innovative approach for creating a supraresilient city/region using black-swan catastrophe and the antifragility concepts. Resilience metrics are formulated as well as methods of assessing damage, interdependence of infrastructures and convergent …

Change Management: Increasing The Odds Of Adoption, Travis Mcneal

Operations Management Presentations

With rapid changes happening all around, organizations are finding themselves in positions where they need their workforce to adapt to new ways of working (technology, structural, process). Organizations develop strategies, programs and projects intended to address these changes. Unfortunately, history is littered with strategies and programs that fail to live deliver on expected results. This has led to the recent rise and proliferation of Change Management as a practice and skill set. Often times, however, Change Management theory is given preeminence over practicality. This webinar will explore practical and actionable ways you can take to immediately increase the odds …

Resilient Design And Crisis Management, Rich Ham

Operations Management Presentations

Explores the techniques to design resilience into systems, business functions, compliance, quality assurance and response to uncertainty. Includes an overview of Federal Emergency Management Agency principles in resilient design and crisis management, including implementation of National Incident Management System processes and industry standards to frame resilient design, procedures and planning documents. Learn to focus on the use of testing, exercises, and implementation of Plan, Do, Check, Act model to continually improve government, business and personal continuity through periods of cascading uncertainty.

Strategic Decision Facilitation: Supporting Critical Assumptions Of The Human In Empirical Modeling Of Pairwise Value Comparisons, Joseph P. Kristbaum, Frank W. Ciarallo

Faculty Publications

Modeling human decision-making is difficult. Decision-makers are typically primed with unique biases that widen the confidence interval of judgment. Therefore, it is important that the human process in the system being modeled is designed to alleviate damaging biases and assumptions in an effort to increase process consistency between decision-makers. In this experiment, it is hypothesized that coupling specific decision-facilitation methods with a specific scale range will affect the consistency between decision-makers. This article presents a multiphase experiment that examines a varying presentation mode as well as scale range to determine how value is determined in subsequent pairwise comparisons of alternatives …

Human Error In Commercial Fishing Vessel Accidents: An Investigation Using The Human Factors Analysis And Classification System, Peter J. Zohorsky

Engineering Management & Systems Engineering Theses & Dissertations

The commercial fishing industry is frequently described as one of the most hazardous occupations in the United States. The objective, to maximize the catch, is routinely challenged by a variety of elements due to the environment, the vessel, the crew, and several external considerations and how they interact with each other. The analysis of fishing vessel accidents can be complicated due to the diverse nature of the industry, including the species caught, the type and size of boat that is employed, how far travelled from their homeport, and the adequacy of the support organizations ensuring safe and uninterrupted operations. This …

Application Of Classification In Machine Learning: An Analysis Of Highway-Rail Grade Crossing Systems Safety, Christopher John Helmer Cox

Theses and Dissertations

Highway-rail grade crossing accidents are the second leading cause of fatalities within the railway transportation industry. Highway-rail grade crossing fatality statistics have failed to improve over the last decade, and in some years have increased. Because of these trends, research has found that considerable Federal funding initiatives exist to support and develop contemporary risk reduction methodologies involving machine learning and artificial intelligence. In accord with these initiatives, this thesis investigates the highway-rail grade crossing safety problem using machine learning to implement an ensemble decision tree-based classification application. The resulting classifier has been validated to achieve a less than three percent …

A Core Reference Hierarchical Primitive Ontology For Electronic Medical Records Semantics Interoperability, Ziniya Zahedi

Engineering Management & Systems Engineering Theses & Dissertations

Currently, electronic medical records (EMR) cannot be exchanged among hospitals, clinics, laboratories, pharmacies, and insurance providers or made available to patients outside of local networks. Hospital, laboratory, pharmacy, and insurance provider legacy databases can share medical data within a respective network and limited data with patients. The lack of interoperability has its roots in the historical development of electronic medical records. Two issues contribute to interoperability failure. The first is that legacy medical record databases and expert systems were designed with semantics that support only internal information exchange. The second is ontological commitment to the semantics of a particular knowledge …

A Framework For Adaptive Capacity In Complex Systems, Abdulrahman Alfaqiri

Engineering Management & Systems Engineering Theses & Dissertations

Complex systems are characterized by their high level of inter-connectivity, ambiguity, and emergence. Therefore, a failure in one element of a system (e.g. cyber layer) due to external or internal disturbances can lead to a cascade effect that may influence all elements of the system. Consequently, the complex system will not be able to perform its functional performance. Threats related to complex systems are very dynamic, fast, complex and damage can be severe. Thus, to respond to the dynamic and unpredictable nature of these threats, complex systems need to be highly adaptive to survive and thrive in the face of …

Cyber-Assets At Risk (Car): Monetary Impact Of Personally Identifiable Information Data Breaches On Companies, Omer Ilker Poyraz

Engineering Management & Systems Engineering Theses & Dissertations

Cyber-systems provide convenience, ubiquity, economic advantage, and higher efficiency to both individuals and organizations. However, vulnerabilities of the cyber domain also offer malicious actors with the opportunities to compromise the most sensitive information. Recent cybersecurity incidents show that a group of hackers can cause a massive data breach, resulting in companies losing competitive advantage, reputation, and money. Governments have since taken some actions in protecting individuals and companies from such crime by authorizing federal agencies and developing regulations. To protect the public from losing their most sensitive records, governments have also been compelling companies to follow cybersecurity regulations. If companies …

Towards A Cyber-Physical Manufacturing Cloud Through Operable Digital Twins And Virtual Production Lines, Md Rakib Shahriar

Graduate Theses and Dissertations

In last decade, the paradigm of Cyber-Physical Systems (CPS) has integrated industrial manufacturing systems with Cloud Computing technologies for Cloud Manufacturing. Up to 2015, there were many CPS-based manufacturing systems that collected real-time machining data to perform remote monitoring, prognostics and health management, and predictive maintenance. However, these CPS-integrated and network ready machines were not directly connected to the elements of Cloud Manufacturing and required human-in-the-loop. Addressing this gap, we introduced a new paradigm of Cyber-Physical Manufacturing Cloud (CPMC) that bridges a gap between physical machines and virtual space in 2017. CPMC virtualizes machine tools in cloud through web services …

All-Metallic Phase Change Thermal Management Systems For Transient Spacecraft Loads, Carl R. Hartsfield, Travis E. Shelton, Brian O. Palmer, Ryan P. O'Hara

Faculty Publications

In this work, we explore the thermal properties of gallium as an effective phase change material for thermal management applications. Thermal storage and dissipation of gallium manufactured heat sinks were compared to conventional phase change heat sinks. The comparison revealed a 50-fold (80 K versus 1.5 K) potential reduction in temperature during the phase change process due to the high density, thermal conductivity, and latent heat of fusion. The gallium creates shallow thermal gradients when transiently heated, producing a nearly isothermal process. Computational estimates using lumped sum parameters were able to provide simple modeling to predict the results. Gallium based …