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Association Between Exposure To Air Pollution And Hippocampal Volume In Adults In The Uk Biobank, Dawson W. Hedges, Lance D. Erickson, Jackie Kunzelman, Bruce L. Brown, Shawn D. Gale
Association Between Exposure To Air Pollution And Hippocampal Volume In Adults In The Uk Biobank, Dawson W. Hedges, Lance D. Erickson, Jackie Kunzelman, Bruce L. Brown, Shawn D. Gale
Faculty Publications
Background: The hippocampus is important for memory processing. Several neuropsychiatric diseases including Alzheimer’s disease are associated with reduced hippocampal volume, and further the hippocampus appears vulnerable to environmental insult. Air pollution has been associated with cardiovascular disease, abnormal brain structure, and cognitive deficits.
Objective: Because of hippocampal vulnerability to environmental insults and based on the association between exposure to air pollution and cognitive function and brain structure, we evaluated the association between exposure to toxins in air pollution and left and right hippocampal volume using brain-imaging and air-pollution data from the UK Biobank, a large community-based dataset.
Methods …