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Mediation And Moderation Of Intergenerational Epigenetic Effects Of Trauma, Stefanie Renee Pilkay Dec 2017

Mediation And Moderation Of Intergenerational Epigenetic Effects Of Trauma, Stefanie Renee Pilkay

Doctoral Dissertations

Trauma and early-life stress have been linked to poor mental and physical health outcomes. In fact, research has identified trauma and stress can influence epigenetic marks on genes that can alter gene activity. It is suspected that epigenetically altered gene activity is involved in behavior and mental health. This may help explain why some individuals don’t experience great benefit from treatment for the effects of stress, and severe mental health symptoms can be chronic for decades or a lifetime. Moreover, some trauma-related mental health symptoms have shown generational patterns that appear linked to epigenetic marks. Therefore, this study sought to …


Developing A Platform For Integrating Disability Issues Into City Municipality Decisions; Case Study: City Of Knoxville, Sravanthi Pamu Dec 2017

Developing A Platform For Integrating Disability Issues Into City Municipality Decisions; Case Study: City Of Knoxville, Sravanthi Pamu

Masters Theses

The People with Disabilities (PWD) & Senior Citizen (SC) are isolated from the mainstream society, and they face several barriers in everyday life. There is no communication platform for them to express their concerns, in turn, participate in the city municipality policy decisions related to PWD- & SC-friendly city development. The purpose of this research is to integrate disability and senior citizen issues in the city of Knoxville to the city council decisions. The comprehensive literature search is done to identify the frequently mentioned disability and age-friendly city factors. An effective survey was designed to identify the issues in collaboration …


Preparing The Workforce For Integrated Healthcare, Denise Ratliff Black Aug 2017

Preparing The Workforce For Integrated Healthcare, Denise Ratliff Black

Doctoral Dissertations

Integrated healthcare is recommended to deliver care to individuals with co-occurring medical and mental health conditions. Identifying the knowledge necessary for behavioral health providers to practice in integrated settings, and determining whether a computer application is an effective strategy to disseminate this knowledge, are essential steps to transitioning these individuals to integrated healthcare delivery systems. A literature review of U.S. based publications from 1999 to 2015 identified 68 articles that met inclusion criteria and identified specific knowledge for integrated healthcare settings. A survey completed by 154 behavioral health providers working in integrated healthcare settings examined the extent to which respondents …


Distress During Cancer Treatment And Its Relation To Posttraumatic Stress Symptoms, Matthew Robert Moore Aug 2017

Distress During Cancer Treatment And Its Relation To Posttraumatic Stress Symptoms, Matthew Robert Moore

Doctoral Dissertations

This dissertation focuses on the psychological response to stress in cancer patients. Specifically, it examines the factors which increase the likelihood of experiencing distress and posttraumatic stress (PTSS), as well as the relationship between distress and PTSS. The dissertation is composed of three manuscripts, the first of which presents a review of the current literature on distress and PTSS in adult cancer patient populations. It indicates that distress is prevalent in cancer patient populations, and that increased levels of distress may be related to PTSS. Furthermore, risk and protective factors are identified, including older age and social support, which may …