Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Animals (1)
- Antibiotics, Antitubercular (pharmacology) (1)
- Antimicrobials (1)
- Antimycobacterial Inhibitors (1)
- Benzamides (pharmacology) (1)
-
- Cell Growth Processes (drug effects) (1)
- Cells, Cultured (1)
- Coping (1)
- DecaprenylPhosphoribose (1)
- Dose-Response Relationship, Drug (1)
- Drug Discovery (methods) (1)
- Elder abuse (1)
- Elder mistreatment (1)
- Elder neglect (1)
- Humans (1)
- Institutional responses (1)
- Kidney (1)
- Long-term care (1)
- Macrophages (microbiology) (1)
- Mice (1)
- Microbial Sensitivity Tests (1)
- Microscopy, Confocal (methods) (1)
- Microscopy, Fluorescence (methods) (1)
- Mycobacterium tuberculosis (drug effects, enzymology) (1)
- Nephrology (1)
- Nursing homes (1)
- Prevention (1)
- Principal Component Analysis (1)
- Racemases and Epimerases (antagonists & inhibitors) (1)
- Renal Disease (1)
Articles 1 - 4 of 4
Full-Text Articles in Social Work
High Content Screening Identifies Decaprenyl-Phosphoribose 2’ Epimerase As A Target For Intracellular Antimycobacterial Inhibitors, Thierry Christophe, Mary Jackson, Hee Kyoung Jeon, Denis Fenistein, Monica Contreras-Dominguez, Jaeseung Kim, Auguste Genovesio, Jean-Philippe Carralot, Fanny Ewann, Eun Hye Kim, Sae Yeon Lee, Sunhee Kang, Min Jung Seo, Eun Jung Park, Henrieta Skovierová, Ha Pham, Giovanna Riccardi, Ji Youn Nam, Laurent Marsollier, Marie Kempf, Marie-Laure Joly-Guillou, Taegwon Oh, Won Kyung Shin, Zaesung No, Ulf Nehrbass, Roland Brosch, Stewart T. Cole
High Content Screening Identifies Decaprenyl-Phosphoribose 2’ Epimerase As A Target For Intracellular Antimycobacterial Inhibitors, Thierry Christophe, Mary Jackson, Hee Kyoung Jeon, Denis Fenistein, Monica Contreras-Dominguez, Jaeseung Kim, Auguste Genovesio, Jean-Philippe Carralot, Fanny Ewann, Eun Hye Kim, Sae Yeon Lee, Sunhee Kang, Min Jung Seo, Eun Jung Park, Henrieta Skovierová, Ha Pham, Giovanna Riccardi, Ji Youn Nam, Laurent Marsollier, Marie Kempf, Marie-Laure Joly-Guillou, Taegwon Oh, Won Kyung Shin, Zaesung No, Ulf Nehrbass, Roland Brosch, Stewart T. Cole
Faculty and Staff Publications
A critical feature of Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB), is its ability to survive and multiply within macrophages, making these host cells an ideal niche for persisting microbes. Killing the intracellular tubercle bacilli is a key requirement for efficient tuberculosis treatment, yet identifying potent inhibitors has been hampered by labor-intensive techniques and lack of validated targets. Here, we present the development of a phenotypic cell-based assay that uses automated confocal fluorescence microscopy for high throughput screening of chemicals that interfere with the replication of M. tuberculosis within macrophages. Screening a library of 57,000 small molecules led …
Institutional Responses To Self-Injurious Behavior Among Inmates, Dana D. Dehart, Hayden P. Smith, Robert J. Kaminski
Institutional Responses To Self-Injurious Behavior Among Inmates, Dana D. Dehart, Hayden P. Smith, Robert J. Kaminski
Faculty and Staff Publications
To date, little research has systematically investigated perceptions of mental health professionals regarding perceived motivations for self-injury among prison inmates. To help fill this gap, descriptive techniques were used to examine self-injurious behavior among inmates from the perspective of correctional mental health professionals. A quantitative survey was used to assess perceptions of mental health staff regarding etiology, motivations, and manifestations of self-injury. A qualitative interview component was used to explicate responses from the survey. Findings indicate that inmate cutting, scratching, opening old wounds, and inserting objects were the most commonly witnessed behaviors. There were indications that self-injury occurred regularly and …
Prevention Of Elder Mistreatment In Nursing Homes: Competencies For Direct-Care Staff, Dana Dehart, Jennifer Webb, Carol Cornman
Prevention Of Elder Mistreatment In Nursing Homes: Competencies For Direct-Care Staff, Dana Dehart, Jennifer Webb, Carol Cornman
Faculty and Staff Publications
Existing training on elder mistreatment in nursing homes focuses on detection and reporting of abuse, with little training specifically targeted toward prevention of mistreatment before it occurs. We used qualitative interviews with nursing home staff, policymakers, and related professionals to identify training needs. Based on participant accounts, we drafted a number of competencies essential for caregiver training to prevent mistreatment in nursing homes. Competencies include those dealing with: definitions and policies; risks for mistreatment; communication and respect; and development of a cooperative working environment. Competencies are discussed along with illustrative examples, and implications for practice and policy are addressed.
Emotional Exhaustion And Workload Demands Of Kidney Transplant Social Workers, Joseph R. Merighi, Teri Browne, Sarah Keenan
Emotional Exhaustion And Workload Demands Of Kidney Transplant Social Workers, Joseph R. Merighi, Teri Browne, Sarah Keenan
Faculty and Staff Publications
This exploratory study examined training issues, emotional exhaustion and workload demands in U.S. kidney transplant socialworkers. Online survey data were obtained from 91 respondents who represented all 18 End-Stage Renal Disease networks.Findings indicated that the majority of the respondents’ employers provided resources for educational training and paid timeoff associated with these trainings. With regard to hours per week spent on specific job tasks, respondents indicated that pretransplantactivities were the most time-consuming, followed by post-transplant and inpatient work. Generally, emotionalexhaustion and workload demands were slightly lower than reported for dialysis social workers. Implications for social workpractice and research are discussed.