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Incident Tuberculosis Diagnoses In Children At High Risk For Disease, Milagros Wong, Julia M. Coit, Milagros Mendoza, Silvia S. Chiang, Helen Marin, Jerome T. Galea, Leonid Lecca, Molly F. Franke

Social Work Faculty Publications

We followed 35 children meeting a research definition for unconfirmed tuberculosis (TB) but in whom a pediatric pulmonologist did not diagnose or treat TB. After a median follow-up of 16.4 months, most children were not diagnosed with TB following a comprehensive evaluation. However, 2 were diagnosed with TB, demonstrating high TB risk (6%; exact 95% CI, 1%–19%). In some contexts, researchers may wish to supplement these research definitions with clinical decision data and longitudinal follow-up in order to improve specificity.