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X-Tream: A Novel Dosimetry System For Synchrotron Microbeam Radiation Therapy, M Petasecca, A Cullen, I Fuduli, A Espinoza, C Porumb, C Stanton, A H. Aldosari, E Brauer-Krisch, H Requardt, A Bravin, V Perevertaylo, Anatoly B. Rosenfeld, M L. F Lerch

Anthony A Espinoza Mr

Microbeam Radiation Therapy (MRT) is a radiation treatment technique under development for inoperable brain tumors. MRT is based on the use of a synchrotron generated X-ray beam with an extremely high dose rate ( ~ 20 kGy/sec), striated into an array of X-ray micro-blades. In order to advance to clinical trials, a real-time dosimeter with excellent spatial resolution must be developed for absolute dosimetry. The design of a real-time dosimeter for such a radiation scenario represents a significant challenge due to the high photon flux and vertically striated radiation field, leading to very steep lateral dose gradients. This article analyses …