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Articles 1 - 5 of 5
Full-Text Articles in Science and Technology Studies
Nanoscale Characterization Of Ion Tracks: Mc Simulations Versus Analytical Approach, M U. Bug, E Surdutovich, H Rabus, Anatoly B. Rosenfeld, A V. Solov'yov
Nanoscale Characterization Of Ion Tracks: Mc Simulations Versus Analytical Approach, M U. Bug, E Surdutovich, H Rabus, Anatoly B. Rosenfeld, A V. Solov'yov
Anatoly Rozenfeld
The goal of this work was to investigate the agreement of physical parameters related to the particle track structure on the nanometer scale, obtained by means of a detailed track structure simulation (PTra) as well as by a rapid analytical approach. Parameters describing the tracks of secondary electrons produced by 0.3 MeV/u C6+-ions were of particular interest as those particles are densely ionizing. For this purpose, the target volume in form of a nanometric water cylinder was positioned at different radial distances from the ion trajectory and track structure parameters were determined as function of the radial distance. While the …
Advanced Semiconductor Dosimetry In Radiation Therapy, Anatoly B. Rosenfeld
Advanced Semiconductor Dosimetry In Radiation Therapy, Anatoly B. Rosenfeld
Anatoly Rozenfeld
Modern radiation therapy is very conformal, resulting in a complexity of delivery that leads to many small radiation fields with steep dose gradients, increasing error probability. Quality assurance in delivery of such radiation fields is paramount and requires real time and high spatial resolution dosimetry. Semiconductor radiation detectors due to their small size, ability to operate in passive and active modes and easy real time multichannel readout satisfy many aspects of in vivo and in a phantom quality assurance in modern radiation therapy. Update on the recent developments and improvements in semiconductor radiation detectors and their application for quality assurance …
A Real-Time In Vivo Dosimetric Verification Method For High-Dose Rate Intracavitary Brachytherapy Of Nasopharyngeal Carcinoma, Zhen-Yu Qi, Xiao-Wu Deng, X Cao, Shao-Min Huang, Michael L. Lerch, Anatoly B. Rosenfeld
A Real-Time In Vivo Dosimetric Verification Method For High-Dose Rate Intracavitary Brachytherapy Of Nasopharyngeal Carcinoma, Zhen-Yu Qi, Xiao-Wu Deng, X Cao, Shao-Min Huang, Michael L. Lerch, Anatoly B. Rosenfeld
Anatoly Rozenfeld
Purpose: A real-time in vivo dosimetric verification method using metal-oxide-semiconductor field effect transistor (MOSFET) dosimeters has been developed for patient dosimetry in high-dose rate (HDR) intracavitary brachytherapy of nasopharyngeal carcinoma (NPC). Methods: The necessary calibration and correction factors for MOSFET measurements in 192Iridium source were determined in a water phantom. With the detector placed inside a custom-made nasopharyngeal applicator, the actual dose delivered to the tumor was measured in vivo and compared to the calculated values using a commercial brachytherapy planning system. Results: Five MOSFETs were independently calibrated with the HDR source, yielding calibration factors of 0.48 ± 0.007 cGymV. …
Improvements In Dose Calculation Accuracy For Small Off-Axis Targets In High Dose Per Fraction Tomotherapy, Nicholas Hardcastle, Adam Bayliss, Jeannie Wong, Anatoly B. Rosenfeld, Wolfgang A. Tome
Improvements In Dose Calculation Accuracy For Small Off-Axis Targets In High Dose Per Fraction Tomotherapy, Nicholas Hardcastle, Adam Bayliss, Jeannie Wong, Anatoly B. Rosenfeld, Wolfgang A. Tome
Anatoly Rozenfeld
Purpose: A recent field safety notice from TomoTherapy detailed the underdosing of small, off-axis targets when receiving high doses per fraction. This is due to angular undersampling in the dose calculation gantry angles. This study evaluates a correction method to reduce the underdosing, to be implemented in the current version (v4.1) of the TomoTherapy treatment planning software. Methods: The correction method, termed "Super Sampling" involved the tripling of the number of gantry angles from which the dose is calculated during optimization and dose calculation. Radiochromic film was used to measure the dose to small targets at various off-axis distances receiving …
X-Tream: A Novel Dosimetry System For Synchrotron Microbeam Radiation Therapy, M Petasecca, A Cullen, I Fuduli, A Espinoza, C Porumb, C Stanton, A H. Aldosari, E Brauer-Krisch, H Requardt, A Bravin, V Perevertaylo, Anatoly B. Rosenfeld, M L. F Lerch
X-Tream: A Novel Dosimetry System For Synchrotron Microbeam Radiation Therapy, M Petasecca, A Cullen, I Fuduli, A Espinoza, C Porumb, C Stanton, A H. Aldosari, E Brauer-Krisch, H Requardt, A Bravin, V Perevertaylo, Anatoly B. Rosenfeld, M L. F Lerch
Anatoly Rozenfeld
Microbeam Radiation Therapy (MRT) is a radiation treatment technique under development for inoperable brain tumors. MRT is based on the use of a synchrotron generated X-ray beam with an extremely high dose rate ( ~ 20 kGy/sec), striated into an array of X-ray micro-blades. In order to advance to clinical trials, a real-time dosimeter with excellent spatial resolution must be developed for absolute dosimetry. The design of a real-time dosimeter for such a radiation scenario represents a significant challenge due to the high photon flux and vertically striated radiation field, leading to very steep lateral dose gradients. This article analyses …