Open Access. Powered by Scholars. Published by Universities.®
Science and Technology Studies Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Science and Technology Studies
A Real-Time In Vivo Dosimetric Verification Method For High-Dose Rate Intracavitary Brachytherapy Of Nasopharyngeal Carcinoma, Zhen-Yu Qi, Xiao-Wu Deng, X Cao, Shao-Min Huang, Michael Lerch, Anatoly Rosenfeld
A Real-Time In Vivo Dosimetric Verification Method For High-Dose Rate Intracavitary Brachytherapy Of Nasopharyngeal Carcinoma, Zhen-Yu Qi, Xiao-Wu Deng, X Cao, Shao-Min Huang, Michael Lerch, Anatoly Rosenfeld
Michael L.F. Lerch
Purpose: A real-time in vivo dosimetric verification method using metal-oxide-semiconductor field effect transistor (MOSFET) dosimeters has been developed for patient dosimetry in high-dose rate (HDR) intracavitary brachytherapy of nasopharyngeal carcinoma (NPC). Methods: The necessary calibration and correction factors for MOSFET measurements in 192Iridium source were determined in a water phantom. With the detector placed inside a custom-made nasopharyngeal applicator, the actual dose delivered to the tumor was measured in vivo and compared to the calculated values using a commercial brachytherapy planning system. Results: Five MOSFETs were independently calibrated with the HDR source, yielding calibration factors of 0.48 ± 0.007 cGymV. …