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California State University, San Bernardino

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Impact Of Subjective Cognitive Complaints On Mci Diagnostic Criteria In Alzheimer’S Disease, Rhiannon Rivas Aug 2023

Impact Of Subjective Cognitive Complaints On Mci Diagnostic Criteria In Alzheimer’S Disease, Rhiannon Rivas

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Alzheimer’s disease (AD) is the most commonly occurring neurodegenerative disease characterized by deficits in patient cognition. Mild cognitive impairment (MCI) is defined as an intermediate stage between cognitively normal (CN) and dementia in which the individual experiences some impairment but can function independently. Gold standard MCI criteria requires a subjective cognitive complaint (SCC) in which a patient acknowledges a decline in cognitive ability, however past findings on its validity as a measure of objective impairment have been inconsistent. Biomarkers found in cerebrospinal fluid (CSF) and indicative of neurodegeneration are also used to examine AD progression. Our study investigates if inclusion …