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Full-Text Articles in Psychology
Early Exposure To Traumatic Stressors Impairs Emotional Brain Circuitry, Robert H. Paul, Mayuresh S. Korgaonkar, Cassandra Antees, Leanne M. Williams
Early Exposure To Traumatic Stressors Impairs Emotional Brain Circuitry, Robert H. Paul, Mayuresh S. Korgaonkar, Cassandra Antees, Leanne M. Williams
Psychology Faculty Works
Exposure to early life trauma (ELT) is known to have a profound impact on mental development, leading to a higher risk for depression and anxiety. Our aim was to use multiple structural imaging methods to systematically investigate how traumatic stressors early in life impact the emotional brain circuits, typically found impaired with clinical diagnosis of depression and anxiety, across the lifespan in an otherwise healthy cohort. MRI data and self-reported histories of ELT from 352 healthy individuals screened for no psychiatric disorders were analyzed in this study. The volume and cortical thickness of the limbic and cingulate regions were assessed …
Altered Emotional Interference Processing In The Amygdala And Insula In Women With Post-Traumatic Stress Disorder, Steven E. Bruce, Katherine R. Buchholz, Wilson J. Brown, Laura Yan
Altered Emotional Interference Processing In The Amygdala And Insula In Women With Post-Traumatic Stress Disorder, Steven E. Bruce, Katherine R. Buchholz, Wilson J. Brown, Laura Yan
Psychology Faculty Works
Background: Post-Traumatic Stress Disorder (PTSD) is characterized by distinct behavioral and physiological changes. Given the significant impairments related to PTSD, examination of the biological underpinnings is crucial to the development of theoretical models and improved treatments of PTSD. Methods: We used an attentional interference task using emotional distracters to test for top-down versus bottom-up dysfunction in the interaction of cognitive-control circuitry and emotion-processing circuitry. A total of 32 women with PTSD (based on an interpersonal trauma) and 21 matched controls were tested. Event-related functional magnetic resonance imaging was carried out as participants directly attended to, or attempted to ignore, fear-related …
The Relationship Between Early Life Stress And Microstructural Integrity Of The Corpus Callosum In A Non-Clinical Population, Robert H. Paul, Lorrie Henry, Stuart M. Grieve, Thomas J. Guilmette
The Relationship Between Early Life Stress And Microstructural Integrity Of The Corpus Callosum In A Non-Clinical Population, Robert H. Paul, Lorrie Henry, Stuart M. Grieve, Thomas J. Guilmette
Psychology Faculty Works
Background: Previous studies have examined the impact of early life stress (ELS) on the gross morphometry of brain regions, including the corpus callosum. However, studies have not examined the relationship between ELS and the microstructural integrity of the brain. Previous studies have examined the impact of early life stress (ELS) on the gross morphometry of brain regions, including the corpus callosum. However, studies have not examined the relationship between ELS and the microstructural integrity of the brain. Methods: In the present study we evaluated this relationship in healthy non-clinical participants using diffusion tensor imaging (DTI) and self-reported history of ELS. …