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Full-Text Articles in Psychology
Preclinical Behavioral Assessment Of Chronic, Intermittent Low-Dose Psilocybin In Rodent Models Of Depression And Anxiety, Harmony I. Risca
Preclinical Behavioral Assessment Of Chronic, Intermittent Low-Dose Psilocybin In Rodent Models Of Depression And Anxiety, Harmony I. Risca
Dissertations
Recent studies have demonstrated the clinical efficacy of psychedelic-assisted psychotherapy for treatment-resistant depression and anxiety. Amidst the overall success of recent clinical trials using a single high dose of psilocybin, anecdotal reports indicate anxiolytic and antidepressant effects following a repeated low dose regimen. As therapeutic outcomes are often tightly intertwined with the individual’s subjective experience, animal models are used as objective measures to investigate the underlying mechanisms responsible for the putative antidepressant/anxiolytic effects of psychedelics. Three rodent models predictive of anxiolytic or antidepressant effects were used to evaluate effects of chronic intermittent low dose (CILD) psilocybin treatment; the Light/Dark conflict …
Adherence To A Mindfulness App For College Students With Depression: Patterns, Predictors, And Outcomes, Brynn Marie Huguenel
Adherence To A Mindfulness App For College Students With Depression: Patterns, Predictors, And Outcomes, Brynn Marie Huguenel
Dissertations
National trends indicate that mental health concerns, particularly rates of depression, continue to rise on college campuses; however, treatment utilization remains low. Technology-based mental health interventions, such as mental health apps (MHapps), are a promising means of overcoming treatment barriers. MHapps are effective in improving psychological outcomes, but low rates of adherence are a noted limitation. The current study explored patterns of adherence to a MHapp, investigated the bidirectional relation between adherence and depression, and identified motivational predictors of adherence rates. Undergraduate students (N= 66) reporting clinically-elevated depressive symptoms completed a three-month trial using Headspace, a mindfulness MHapp. Patterns of …