Psychology Commons^™

Cortisol Administration Normalizes Aberrant Functional Connectivity In Women With Depression, Adam C. Runyan

Dissertations

Previous resting-state functional connectivity (rsFC) research has identified aberrant connectivity in several large brain networks in depression, including the default mode (DMN), frontoparietal (FPN), and salience networks (SN). Connectivity of these networks is also related to depressive symptom severity and is affected by cortisol levels. To our knowledge, this is the first study to investigate the effects of acute cortisol administration on rsFC of DMN, FPN, and SN in individuals varying in depression history and severity. We collected resting-state fMRI scans for 74 women with and without a history of depressive disorder after administration of cortisol and placebo using a …

Assessing A Cognitive Model Of Trauma-Related Sleep Disturbance, Rebecca Chesher

Dissertations

Sleep disturbance is a symptom of many mental health disorders that may negatively affect cognition and mood. Trauma-related sleep disturbance is a core reaction of traumatic stress and PTSD, similar to symptoms experienced by individuals with insomnia or other sleep-wake disorders. Although the cause and symptom progression of trauma-related sleep disturbance may be very different, research and clinical practice assess and treat it with measures and interventions designed for general insomnia. Using a cognitive model of insomnia modified for trauma-related sleep disturbance, the current study assessed the relations between select trauma and sleep variables within the proposed constructs of: 1) …

Understanding Comorbid Depression In The Context Of Ptsd Through Underlying Dimensions, Melissa Turkel

Dissertations

Depression co-occurs with Posttraumatic Stress Disorder at a high rate, resulting in numerous complications for pathology and treatment. More research is needed regarding variables that may explain this common comorbidity. One possible variable is that of underlying dimensions, latent factors that give rise to these manifestations of psychopathology. This study explored potential underlying mechanisms of comorbid PTSD and depression, including negative affect, rumination, emotion dysregulation, neuroticism, and behavioral inhibition. While previous studies have investigated these dimensions individually, there is a dearth of research that simultaneously investigates multiple dimensions or determines the relative contributions of underlying dimensions to psychopathology. Thus, the …

The Influence Of Stressful Life Events On The Development Of Type 2 Diabetes, Joshua Minks

Dissertations

This study examined the relationship between distress and the development of Type 2 diabetes mellitus (T2DM) in the presence of established risk factors. Distress secondary to mental health disparities, stressful life events, and work conditions has been shown to promote insulin resistance and the development of T2DM.

Subjects (N=79) diagnosed with T2DM within the previous six months were recruited from SSM Health Centers and VA Medical Centers in the greater St. Louis area. They completed the Recent Life Changes Questionnaire, ENRICHD Social Support Instrument, and a demographic survey and analyses were conducted to determine differences between the veteran …

The Relation Of Anxiety, Depression, And Stress To Binge Eating Behavior, Diane L. Rosenbaum

Dissertations

Binge eating is an impairing and prevalent problem. Theories of binge eating suggest negative affect is of primary importance in the development and maintenance of binge eating behavior. To date, investigations of binge eating have often examined depression, however relatively little is known about other psychological factors. The current study aimed to extend the literature by examining several psychological factors in relation to binge eating behavior. Specifically, the relation between binge eating behavior and three psychological factors, depression, anxiety and stress, were examined. Data were collected via online surveys from a community sample of men and women of diverse backgrounds. …

Structural Models Of Comorbid Anxiety And Depression In A Primary-Care Older Adult Sample: Effect Of Medical Illness Severity, Threat, Chronicity, And Progressiveness On Model Fit, William Michael Palmer

Dissertations

Recent research suggests that anxiety disorders may be more common in later life than previously thought. Among other factors, the presence of comorbid mood disorders and medical illness confounds accurate assessment and diagnosis of these conditions in the elderly. There have been few studies, however, examining the structural relationships between anxiety and depression with older-adult samples, and even fewer have considered the effect of medical illness on these relationships. This study examined three established structural models of anxiety and depression, using a clinical sample of older adults seeking treatment in a primary-care setting (N = 2,163). It was hypothesized that …

The Effects Of Rumination On Problem-Solving Self-Efficacy And Self-Efficacy For Controlling Upsetting Thoughts In The Context Of Depressive Symptoms, Christina Marcia Gilliam

Dissertations

Two cognitive variables that are of interest in their role in depression are self-efficacy and rumination. Self-efficacy refers to individuals¿ own appraisal of their ability to successfully accomplish a domain of tasks (Bandura, 1977). Rumination, as defined by Response Styles Theory (Nolen-Hoeksema, 1991), refers to the process of repetitively and passively thinking about negative emotions, consequences, and symptoms of distress. Although the relationship between these two constructs and depression has been examined in both experimental and correlational studies, there has been minimal research on the relationship between self-efficacy and rumination among depressed individuals. The present study was intended to replicate …