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Psychology Commons

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Anxiety

2005

LSU Doctoral Dissertations

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Serotonin And Stress Responding In Animals: Role Of 5-Ht.2a/C Receptors In The Central And Peripheral Nervous Systems, Sarah Mathews Uzelac Jan 2005

Serotonin And Stress Responding In Animals: Role Of 5-Ht.2a/C Receptors In The Central And Peripheral Nervous Systems, Sarah Mathews Uzelac

LSU Doctoral Dissertations

Behavioral responses to stressors can be influenced in different ways by both serotonin (5-HT) agonists and antagonists. Further study, of both different stressors as well as different 5-HT agents, is needed to clarify the place of 5-HT in stress responding. To date, no published report has investigated the influence of centrally and/or peripherally administered 5-HT2A/C agonist DOI or the 5-HT2A/C antagonist ketanserin on behaviors evoked by tail pinch or open field stressors. Five separate, related experiments were conducted to investigate this influence. It was hypothesized that that peripherally (Experiment 1), centrally (Experiment 2), and centrally + peripherally (Experiment 3) injected …