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Anxiety

Honors Scholar Theses

2012

Articles 1 - 2 of 2

Full-Text Articles in Psychology

Habituation Effect In Attention Modification Training For Obsessive-Compulsive Disorder, Olivia E. Bogucki May 2012

Habituation Effect In Attention Modification Training For Obsessive-Compulsive Disorder, Olivia E. Bogucki

Honors Scholar Theses

Attention biases influence the type of information that captures an individual’s attention. Cognitive theories of obsessive-compulsive disorder (OCD) state that attention biases cause an increased amount of attention to personally relevant threatening information. Previous studies support this connection, and have examined attention modification training (AMT) as a means to direct attention away from threatening information for various anxiety disorders, including OCD. Results show that attention biases toward threatening information decrease during a single training session of AMT, which may be a result of habituation to threat. However, there is a lack of longitudinal data investigating the number of AMT sessions …


Adenosine-Dopamine Interactions In The Open Field Arena: Studies Related To Locomotion And Anxiety, Rothem Kovner May 2012

Adenosine-Dopamine Interactions In The Open Field Arena: Studies Related To Locomotion And Anxiety, Rothem Kovner

Honors Scholar Theses

Nucleus accumbens dopamine (DA) is an important regulator of locomotion. The neuromodulator adenosine also has a role in regulating locomotion. The adenosine A2A receptor subtype is colocalized with DA D2 receptors on medium spiny neurons in the striatum and nucleus accumbens. Interactions between adenosine A2A and DA D2 receptor antagonists are significant for regulating various aspects of motor and motivational function. The adenosine A2A antagonist MSX-3 has been shown to reverse the suppression of locomotion induced by the DA D2 antagonist eticlopride. The structure of MSX-3 was modified to produce the prodrug MSX-4 which has high oral …