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Identifying Component-Processes Of Executive Functioning That Serve As Risk Factors For Alcohol-Related Aggression, Aaron John Godlaski
Identifying Component-Processes Of Executive Functioning That Serve As Risk Factors For Alcohol-Related Aggression, Aaron John Godlaski
University of Kentucky Doctoral Dissertations
The present investigation determined how different component-processes of executive functioning (EF) acted as risk factors for intoxicated aggression. Participants were 512 (246 men and 266 women) healthy social drinkers between 21 and 35 years of age. EF was measured using the Behavior Rating Inventory of Executive Functioning – Adult Version (BRIEF-A; Roth, Isquith, & Gioia, 2005) that assesses nine EF components. Following the consumption of either an alcohol or a placebo beverage, participants were tested on a modified version of the Taylor Aggression Paradigm (Taylor, 1967) in which mild electric shocks were received from, and administered to, a …
Polyamine Modulation In Alcoholism: Examination Using A Novel Screening Procedure Designed To Predict Anti-Relapse And Neuroprotective Efficacy, J. Ben Lewis
University of Kentucky Doctoral Dissertations
Alcohol dependence is a major public health concern. Despite the FDA’s approval of multiple anti-relapse drugs, relapse rates remain unacceptably high. Furthermore, cognitive deficits among chronic drinkers are evident and are suggested to contribute to relapse risk. Current evidence suggests that several critical features of alcoholism and alcohol-associated neurodegeneration are mechanistically linked to glutamatergic actions; specifically, they appear positively affected by glutamatergic inhibition, particularly inhibition via polyamine modulation of a subpopulation of n-methyl-d-aspartate receptors. The current project was designed to evaluate the performance of two putative polyamine modulators (JR-220 and CP-101,606) in a variety of screens designed …
Manipulation Of Positive Emotion And Its Effects On Negative Outcomes Of Gambling Behaviors And Alcohol Consumption: The Role Of Positive Urgency, Melissa A. Cyders
Manipulation Of Positive Emotion And Its Effects On Negative Outcomes Of Gambling Behaviors And Alcohol Consumption: The Role Of Positive Urgency, Melissa A. Cyders
University of Kentucky Doctoral Dissertations
The current pair of experimental studies sought to further validate the role of positive urgency (acting rashly when in an extreme positive emotional state) as a risk factor for impulsive and maladaptive behavior. Previous research has supported the use of emotion-based dispositions to rash action in predicting a wide range of maladaptive acts. However, that research relied on self-reported behavior, thus lacking (1) tight experimental controls and (2) direct observation of risky behaviors. In the two experimental studies described here, I found that, among college students, (1) previous cross-sectional relationships between risk and positive urgency were supported (n = 104), …