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Alcohol

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Butler University

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Full-Text Articles in Psychology

Remember That Party Last Night? Examining The Effects Of Binge-Like Alcohol On Memory, Anna Thomas Jan 2020

Remember That Party Last Night? Examining The Effects Of Binge-Like Alcohol On Memory, Anna Thomas

Undergraduate Honors Thesis Collection

Alcohol is a widely available drug that is often abused. Studies have shown alcohol-induced memory loss in humans and animals; however, the large amount of alcohol often necessary to observe such loss and use of involuntary drinking paradigms in animals makes translation difficult. The current study was designed to look at voluntary binge-like drinking behavior and memory in rodents. We anticipated decreases in working memory function following consumption of binge-like alcohol in mice and expected a greater deficit in mice experiencing acute withdrawal during the memory task. The present study explored drinking behaviors in adult C57BL/6J mice (18 male, 18 …


Anxiety-Inducing Effects Of Alcohol And Caffeine In C57bl/6j Mice, Melissa Evans Jan 2020

Anxiety-Inducing Effects Of Alcohol And Caffeine In C57bl/6j Mice, Melissa Evans

Undergraduate Honors Thesis Collection

Caffeine and alcohol are two of the most popular and legal drugs around the world. In America, both drugs are easily accessible, which has contributed to frequent use of the drugs in tandem. Previous studies have revealed much about the mechanisms of each drug, but the effects of co-consumption are not yet fully understood. One concern is that caffeine could reduce how intoxicated a person feels, leading to an increase in alcohol consumption or other risky behaviors. Withdrawal is also a concern as it helps maintain the cycle of substance abuse. This study was designed to examine consumption patterns of …


Drinking In The Dark: Voluntary Co-Consumption Of Nicotine And Alcohol For Binge-Like Drinking Behavior In Mice, Katherine Benson Jan 2019

Drinking In The Dark: Voluntary Co-Consumption Of Nicotine And Alcohol For Binge-Like Drinking Behavior In Mice, Katherine Benson

Undergraduate Honors Thesis Collection

Alcohol and nicotine are two of the most commonly abused drugs across the United States. Given the high rates of comorbidity, it remains a pressing public health concern to determine how the two drugs interact within the CNS, and how this impacts addictive behavior. The present study investigated the effect of comorbid abuse of nicotine and alcohol on stress and anxiety-like withdrawal symptoms, as both are associated with increased rates of relapse. A voluntary co­-consumption, two-bottle choice paradigm was used with nicotine and alcohol to induce binge-­like drinking behavior in mice following the drinking in the dark (DID) model of …


“Wide-Awake Drunk”: Observing The Combined Effects Of Alcohol And Caffeine On Somatic Withdrawal Signs In C57bl/6j Mice, Montana Jenkins Jan 2019

“Wide-Awake Drunk”: Observing The Combined Effects Of Alcohol And Caffeine On Somatic Withdrawal Signs In C57bl/6j Mice, Montana Jenkins

Undergraduate Honors Thesis Collection

Caffeine is one of the most widely used psychoactive stimulants in the world and is often used in combination with other substances. The combination of caffeine and alcohol has been shown to induce a stimulated, rather than sedated state, which may result in increased alcohol-attributable accidents (e.g., drunk driving, unprotected sex, and over intoxication). Preclinical research has found mixed results regarding the co-consumption of caffeine and alcohol – some found that caffeine increases alcohol intake while others the opposite. The current study expanded on previous research by testing the effects of combined caffeine and alcohol exposure in a binge-like, mouse …