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Full-Text Articles in Psychology
The Role Of Septal Vasopressin Innervation In Paternal Behavior In Prairie Voles (Microtus Ochrogaster), Geert De Vries, Z. X. Wang, C. F. Ferris
The Role Of Septal Vasopressin Innervation In Paternal Behavior In Prairie Voles (Microtus Ochrogaster), Geert De Vries, Z. X. Wang, C. F. Ferris
Geert De Vries
After being paired with females, male prairie voles show major changes in their social behaviors among which is an increase in paternal responsiveness. These changes are accompanied by fluctuations in the density of the [Arg8]vasopressin-immunoreactive (AVP-ir) fibers in the lateral septum, suggesting that septal AVP might be involved in these changes. To explore a possible involvement of septal AVP in paternal responsiveness, we tested whether injections of saline, AVP, or the V1a receptor antagonist [1-(beta-mercapto-beta, beta-cyclopentamethylenepropionic acid),2-(O-methyltyrosine]AVP [d(CH2)5Tyr(Me)AVP] into the lateral septum influenced the four most prominent paternal activities displayed by male prairie voles; grooming, crouching over, contacting, and retrieving …
Sex Differences In The Effects Of Testosterone And Its Metabolites On Vasopressin Messenger Rna Levels In The Bed Nucleus Of The Stria Terminalis Of Rats, Geert De Vries, Z. X. Wang, N. A. Bullock, S. Numan
Sex Differences In The Effects Of Testosterone And Its Metabolites On Vasopressin Messenger Rna Levels In The Bed Nucleus Of The Stria Terminalis Of Rats, Geert De Vries, Z. X. Wang, N. A. Bullock, S. Numan
Geert De Vries
Male rats have about two times as many steroid-responsive vasopressin- immunoreactive (AVP-ir) neurons in the bed nucleus of the stria terminalis (BST) as female rats. This sex difference does not depend on differences in circulating hormone levels, since it persists in males and females that are treated with similar levels of testosterone. To analyze the cellular basis of this sex difference, we compared the effects of testosterone and its metabolites on AVP mRNA expression in the BST of males and females that were gonadectomized at 3 months of age. When rats received implants of Silastic tubing filled with testosterone, males …
Distribution Of Androgen Receptor Immunoreactivity In Vasopressin- Immunoreactive And Oxytocin-Immunoreactive Neurons In The Male Rat Brain, Geert De Vries, L Zhou, J. D. Blaustein
Distribution Of Androgen Receptor Immunoreactivity In Vasopressin- Immunoreactive And Oxytocin-Immunoreactive Neurons In The Male Rat Brain, Geert De Vries, L Zhou, J. D. Blaustein
Geert De Vries
Arginine vasopressin-immunoreactive (AVP-ir) neurons in the bed nucleus of stria terminalis (BST) and medial amygdaloid nucleus are very responsive to gonadal hormones. After gonadectomy, these neurons lose their AVP immunoreactivity and stop expressing AVP mRNA. Testosterone treatment reverses these changes, acting via androgen as well as estrogen receptor-mediated mechanisms. Although AVP-ir neurons contain estrogen receptor immunoreactivity, it is not known whether they also contain androgen receptor immunoreactivity. To answer this question, brains of male rats were stained immunocytochemically for AVP as well as for androgen receptors. In the BST and medial amygdaloid nucleus, respectively, 90.5% and 91.2% of the AVP-ir …