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Full-Text Articles in Psychology

A Mouse Model Of Toluene Abstinence-Induced Pathology, Sean Callan Jan 2016

A Mouse Model Of Toluene Abstinence-Induced Pathology, Sean Callan

Wayne State University Dissertations

The intentional misuse of volatile solvents is a persistent public health concern. Limited self-report data suggests that chronic inhalant abusers experience withdrawal symptoms including anxiety and seizure symptoms. However, these symptoms have never been explored in a preclinical model and are not considered part of the DSM-V criteria for an Inhalant Use Disorder. For this experiment, 76 young adult male Swiss Webster mice were exposed to either 5,000 ppm toluene vapor or air (0 ppm) for 24 consecutive hours beginning on postnatal day (PND) 30. Following the 24 hour exposure, mice were allowed to recover for 3 hours before behavioral …


Consumer Neuroscience: A Multi-Disciplinary Approach To Marketing Leveraging Advances In Neuroscience, Psychology And Economics, Bridget E. Blum Jan 2016

Consumer Neuroscience: A Multi-Disciplinary Approach To Marketing Leveraging Advances In Neuroscience, Psychology And Economics, Bridget E. Blum

CMC Senior Theses

For decades, neuroscience has greatly contributed to our foundational understanding of human behavior. More recently, the findings and methods of neuroscience have been applied to study the process of decision-making in order to offer advanced insights into the neural mechanisms that influence economic and consumer choices. In this thesis, I will address how customized marketing strategies can be enriched through the integration of consumer neuroscience, an integrative field anchored in the biological, cognitive and affective mechanisms of consumer behavior. By recognizing and utilizing these multidisciplinary interdependencies, marketers can enhance their advertising and promotional mix to elicit desired neural and affective …


Age-Related Changes In Hippocampal Arc Expression Following Minimal Behavioural Induction, Irina V. Odintsova Jan 2016

Age-Related Changes In Hippocampal Arc Expression Following Minimal Behavioural Induction, Irina V. Odintsova

Theses and Dissertations (Comprehensive)

Normal ageing is associated with significant changes in cognitive function, including the decline of some forms of memory. The hippocampal formation is critical to learning and memory function, and plasticity in this region declines with age. Additionally, age-related differences in plasticity are greatest at lower levels of stimulation, thus peri-threshold plasticity may be of the greatest relevance for age-related changes in cognition. Moreover, the hippocampus is prone to changes in the expression of gene products that mediate plasticity with age. The current thesis attempts to link these observations by measuring hippocampal expression of Arc, an immediate-early gene that is critical …