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Articles 1 - 18 of 18
Full-Text Articles in Psychology
Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki
Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki
Legacy Theses & Dissertations (2009 - 2024)
AbstractFear is an evolutionarily conserved mechanism that allows an organism to discern potential harm and act accordingly by engaging in defensive behaviors. While fear is an adaptive response, dysregulation of fear by means of a traumatic event can lead to psychiatric conditions such as post-traumatic stress disorder (PTSD). Animal research using rodents in Pavlovian context fear conditioning experiments allows for the ability to study the underlying neural circuitry of threat-appropriate and aberrant fear learning and memory that may contribute to PTSD. However, despite reports that women are more than two times more likely to develop PTSD compared to men, the …
Behavioral, Endocrine, And Neural Responses To Stress In Postpartum And Nulliparous Rats : Potential Mechanisms Of Postpartum Stress Resilience, Joanna Medina
Legacy Theses & Dissertations (2009 - 2024)
Major depressive disorder is one of the most pervasive psychiatric illnesses in the United States. Women are at greater risk for developing depression, particularly during their childbearing years. Approximately 17% of new mothers develop postpartum depression within 4 weeks after parturition. The risk for postpartum depression is even greater in women who do not breastfeed or stop breastfeeding early. Major depressive disorder and postpartum depression share the same symptomology and common etiological bases. Dysregulated stress responses, dopamine activity, and neuroinflammation are recognized mechanisms for depression. The transition to motherhood encompasses physiological and behavioral adaptations in the brain essential for ensuring …
The Effects Of Parental Factors And Personal Attributes On Birth Control Use Under The Genetic Influences Of 5-Httlpr Among Adolescents, Hyun-Jin Cho
Legacy Theses & Dissertations (2009 - 2024)
The purpose of this study was (a) to examine relationships between parental influences and personal attributes on birth control use and (b) to identify genetic influences on such relationships by comparing the frequencies of common genetic variants—short allele vs. long allele—in 5-HTTLPR among adolescents (N = 5,852). Data from the Wave 1 and Wave 4 of the National Longitudinal Study of Adolescent Health were used to examine the birth control use of adolescents who were in 7th through 12th grade in 1994–1995. Multi-group Structural Equation Modeling analyses were used to identify the relationship among factors. Results did not find significant …
The Role Of Progesterone Receptor In The Developing Medial Preoptic Nucleus, Diana Lalitsasivimol
The Role Of Progesterone Receptor In The Developing Medial Preoptic Nucleus, Diana Lalitsasivimol
Legacy Theses & Dissertations (2009 - 2024)
Numerous neurodevelopmental and neuropsychiatric diseases have a distinct sex bias in
Characterization Of A Novel, Stress-Responsive Sexually Dimorphic Corticotropin-Releasing Factor Receptor 1 (Crfr1) Nucleus In The Rostral Anteroventral Periventricular Nucleus Of The Mouse, Zachary Julius Rosinger
Characterization Of A Novel, Stress-Responsive Sexually Dimorphic Corticotropin-Releasing Factor Receptor 1 (Crfr1) Nucleus In The Rostral Anteroventral Periventricular Nucleus Of The Mouse, Zachary Julius Rosinger
Legacy Theses & Dissertations (2009 - 2024)
Within the United States, women are at double the risk of men to develop a stress-related mood disorder (e.g., anxiety or depression) during their reproductive years (Kornstein et al., 2000; Kessler et al., 2005). Many factors contribute to the potential sex difference in such disorders, including gonadal hormones (hypothalamic-pituitary-gonadal axis; HPG) and how they interact with the stress response system, or hypothalamic-pituitary-adrenal (HPA) axis. Corticotropin-releasing factor (CRF) signals through binding the GS-coupled receptor, CRF receptor 1 (CRFR1), and activity between CRF/CRFR1 regulates the hormonal and behavioral stress response (Chen et al., 1993; Bale and Vale, 2004; Heinrichs et al., 1995; …
An Investigation Of Implicit And Explicit Memory In The Survival Memory Paradigm, Allison M. Wilck
An Investigation Of Implicit And Explicit Memory In The Survival Memory Paradigm, Allison M. Wilck
Legacy Theses & Dissertations (2009 - 2024)
Robust support has been found for a survival processing effect on memory when information is encoded for its fitness-relevance (Nairne, Thompson, & Pandeirada, 2007). However, support for this effect has been limited to forms of memory that require intentional, explicit retrieval processes. Thus far, the literature has failed to identify the effect in implicit, automatic memory using conceptual and perceptual production tasks (McBride, Thomas, & Zimmerman, 2013; Tse & Altarriba, 2010). In the current study, an alternative implicit memory test that employs different memory processes was employed in a further attempt to examine the survival processing effect in implicit memory. …
The Effects Of Pre-Pregnancy Tobacco Use On Food Cravings And Weight Gain In Pregnancy, Lauren E. Blau
The Effects Of Pre-Pregnancy Tobacco Use On Food Cravings And Weight Gain In Pregnancy, Lauren E. Blau
Legacy Theses & Dissertations (2009 - 2024)
Smoking cessation is associated with greater frequency of food cravings, even when controlling for body mass index. Recent studies have indicated similarities between obese women and women who smoke tobacco in mood states and food craving frequency. This is consistent with the common substrate hypothesis, which postulates that shared neural pathways mediate craving across multiple domains, and could explain why it is common for women attempting to quit smoking to gain weight. Smoking cessation prior to pregnancy is strongly encouraged due to the adverse effects of tobacco use on the developing fetus. Studies have shown that women who quit smoking …
A "Default Option" While Online Grocery Shopping To Enhance Nutrition Within A Food Insecure Population, Jaime Ashley Coffino
A "Default Option" While Online Grocery Shopping To Enhance Nutrition Within A Food Insecure Population, Jaime Ashley Coffino
Legacy Theses & Dissertations (2009 - 2024)
There is a need for sustainable interventions that improve diet-related health within the food insecure community. We examined if use of a “default” prefilled online grocery shopping cart, compared to nutrition education, would result in the purchase of healthier food items. Fifty participants (M age = 46.4 ± 12.46 years; M body mass index = 28.59 ± 6.48 kg/m2; 74.0% male) were randomized to: (1) read a brochure containing nutrition information (n = 23) or (2) be presented with a “default” prefilled online shopping cart containing groceries that meet nutritional guidelines to which they could freely make changes before completing …
Reduced Conscious Recollection And Its Detection In Three Performance Validity Tests : A Dual Task Interference Investigation, Graham Michael Silk-Eglit
Reduced Conscious Recollection And Its Detection In Three Performance Validity Tests : A Dual Task Interference Investigation, Graham Michael Silk-Eglit
Legacy Theses & Dissertations (2009 - 2024)
Performance validity is an essential component of neuropsychological assessment. Research suggests that examinees with specific neurological conditions cannot successfully complete certain performance validity tests (PVTs). However, very little basic research has explored the information processing underlying performance on PVTs that might explain why these examinees fail certain PVTs. The current study used a dual task interference paradigm to isolate the impact of reducing conscious recollection on the performance of three PVTs, the Test of Memory Malingering (TOMM), Victoria Symptom Validity Test (VSVT), and Word Memory Test (WMT). One-hundred-and-twenty-six non-clinical undergraduate research participants were administered these three PVTs as part of …
What's In A Kiss? : The Role Of Kissing In Romantic Relationships, Kristina N. Spaulding
What's In A Kiss? : The Role Of Kissing In Romantic Relationships, Kristina N. Spaulding
Legacy Theses & Dissertations (2009 - 2024)
A strong understanding of the role of kissing has important theoretical implications; however little research has been done on kissing in romantic relationships. This study aimed to examine the role of kissing in (a) mate assessment, (b) initiating arousal and (c) maintenance of an emotional bond. Data were collected by surveying college students at a public university in the northeast. The first survey (n = 121) examined the memory of the first kiss compared to other sexual “firsts” as well as the relationship between the first kiss and relationship outcome. Memories of the first kiss were weaker than memories of …
Mediation Of Recurrent Hypoglycemia's Physiological And Behavioral Effects In The Hippocampus By Glucocorticoids, Danielle Osborne
Mediation Of Recurrent Hypoglycemia's Physiological And Behavioral Effects In The Hippocampus By Glucocorticoids, Danielle Osborne
Legacy Theses & Dissertations (2009 - 2024)
Recurrent hypoglycemia (RH) occurs with the over administration of insulin resulting in severe hypoglycemia on a repetitive basis. This occurs most commonly among Type I Diabetics who rely on exogenous insulin replacement for management of their disease; however it is becoming increasingly common among Type II Diabetics. Although cognitive deficits are reported during hypoglycemia, the period following restoration of euglycemia has been denoted by improved hippocampally-mediated short-term and working memory in humans and rodents, respectively. RH is also associated with an altered glucocorticoid secretion profile in response to hypoglycemia. In vitro and in vivo approaches were utilized with the goal …
The Role Of Igf-Ii In Memory Enhancement : Implications For Autism Spectrum Disorders, Amy S. Kohtz
The Role Of Igf-Ii In Memory Enhancement : Implications For Autism Spectrum Disorders, Amy S. Kohtz
Legacy Theses & Dissertations (2009 - 2024)
Cognitive and memory impairments significantly affect multiple domains in life and play major roles in disease. Identifying critical mechanisms and factors that mediate memory consolidation and enhancement may represent an important approach for increasing cognition in normal adults and preventing or treating cognitive impairments. The expression of the C/EBP- target gene insulin-like growth factor 2, (IGF-II) is required for memory consolidation; furthermore, IGF-II administration during memory consolidation produces memory enhancement, increased memory persistence and prevents forgetting. In this thesis, I investigated the therapeutic potential of IGF-II to promote memory consolidation when administered systemically. In addition, I investigated one particularly interesting …
The Role Of Progestogen Neurosteroids In Behaviors Relevant For Autism Spectrum Disorders, Danielle Christine Llaneza
The Role Of Progestogen Neurosteroids In Behaviors Relevant For Autism Spectrum Disorders, Danielle Christine Llaneza
Legacy Theses & Dissertations (2009 - 2024)
Autism spectrum disorder (ASD) affects children across the U.S. and is characterized by deficits in social communication and restrictive/repetitive behaviors, for which few therapeutic interventions have been successful. Steroid hormones, such as progesterone (P4) and its metabolite, 5α-pregnan-3α-ol-20-one (3α,5α-THP), can exert neuroprotective effects, influence synaptic morphology, mediate behavioral outcomes, and influence stress-responding. In this thesis, the behaviors and baseline levels of the stress hormone, corticosterone, P4, and 3α,5α-THP are investigated in BTBR T+ Itpr3tf/J (BTBR) mice, a proposed ASD model. It was hypothesized that BTBR mice would show abnormalities in behaviors and in levels of steroids and neuroendocrine factors. Results …
Physiology Of Yawning : Proximate Mechanisms Supporting An Ultimate Function, Melanie Lee Shoup-Knox
Physiology Of Yawning : Proximate Mechanisms Supporting An Ultimate Function, Melanie Lee Shoup-Knox
Legacy Theses & Dissertations (2009 - 2024)
Recent research suggests that yawning functions to cool the brain during periods of mild hyperthermia. Evidence for this hypothesis is largely behavioral, and includes reports of increased yawning during increases in ambient temperature and times of stress as well as an amelioration of yawning upon nasal breathing and forehead cooling. Little research has been published on the physiological mechanisms supporting a brain cooling function, however. The current set of studies explores human and animal physiological parameters in search of evidence of brain cooling during yawning. In humans, heart rate, skin temperature, and skin conductance findings suggest that yawning involves an …
The Differential Effects Of Genetic And Dietary Alterations In Folate Status On Prefrontal Cortical Functions, Jessica Amanda Ash
The Differential Effects Of Genetic And Dietary Alterations In Folate Status On Prefrontal Cortical Functions, Jessica Amanda Ash
Legacy Theses & Dissertations (2009 - 2024)
Folate status plays an essential role in embryogenesis and brain development; however, its importance in supporting cognitive functioning throughout adulthood is less clear. The present study was interested in examining the effects of genetic and dietary alterations in folate status on prefrontal cortical functions in mice, modeling a common polymorphism in the MTHFD1 gene in folate metabolism. A factorial design was used crossing two genotypes (mice with a gene trap insertion in the Mthfd1 gene exhibiting 50% decreased Mthfd1 expression: Mthfd1gt/+ mice or wildtype mice) with two levels of dietary folate (folate sufficient or folate deficient). The mice were tested …
Darwin's Other Idea : Sexual Selection, Gender And Violence, Robert Samuel Moschgat
Darwin's Other Idea : Sexual Selection, Gender And Violence, Robert Samuel Moschgat
Legacy Theses & Dissertations (2009 - 2024)
This dissertation provides an empirical exploration of Darwin's theory of sexual selection, which views the male propensity to engage in short term mating strategies--sexual promiscuity and violence--as the result of sexual selection. Within an environmental context, biological father and mother household presence are expected to inhibit the initiation of short-term mating strategies and increase parental investment--paternal and maternal attachments, supervision, and protection. Whereas, structural disadvantage--living in poverty and in dangerous neighborhoods--is predicted to increase the initiation of a short-term mating strategies and compromise the parents' ability to protect their children and by weakening paternal and maternal attachments, thereby increasing the …
The Role Of Androstane Neurosteroids In Alcohol-Mediated Social Behavior, Jason J. Paris
The Role Of Androstane Neurosteroids In Alcohol-Mediated Social Behavior, Jason J. Paris
Legacy Theses & Dissertations (2009 - 2024)
Androgenic steroids, such as testosterone, may influence the propensity for aggression in both people and animals. Some of testosterone's effects on aggression may be due, in part, to its metabolic products that are 5á-reduced and 3á-hydroxylated to form, 3á-androstanediol (3á-diol), which can also enhance aggression in mice. Notably, alcohol (EtOH) consumption facilitates aggression in people and animals, particularly among those predisposed to act aggressively. In rats, EtOH can increase 3á-diol in prefrontal cortex, which may facilitate aggression. The present work aimed to elucidate the role of 3á-diol for EtOH-enhanced aggression. We hypothesized that EtOH would enhance inter-male aggression, social dominance, …
Effects Of Early Developmental Stress On Adult Physiology And Behavior, Michael James Frederick
Effects Of Early Developmental Stress On Adult Physiology And Behavior, Michael James Frederick
Legacy Theses & Dissertations (2009 - 2024)
Events during early development can have long-term effects on physiology and behavior. While extreme developmental stress is known to be associated with a variety of behavioral problems, it is less well understood how milder stress may affect behavior, personality, and reproductive success. This research project assessed a variety of behavioral dimensions in a college age sample, while assessing early development using size at birth, fluctuating asymmetry, and retrospective surveys. Maternal stress during pregnancy was found to reduce adolescent growth spurts and adult handgrip strength in the offspring. In males, lower birth weights were associated with higher scores of impulsivity and …