Psychology Commons^™

The Effects Of Two Types Of Frontal Lesions On Reversal Learning And Activity Level In Rats, Meredith Ann Davison

University of the Pacific Theses and Dissertations

The purpose of this experiment was to compare traditional frontal pole lesions (FP) with lesions of the median dorsal nucleus projection (MDNP) described by Leonard. First, a comparison was made on the retention of spatial discrimination learning and the new learning of spatial discrimination reversals between these two groups of frontally lesioned rats. It was hypothesized that the most severe deficits in spatial reversal learning would be shown in rats receiving MDNP lesions since this area of the rat cortex appears to be homologous to the frontal cortex of higher species according to Leonard’s results. Second, activity was measured on …