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Persistence Of One-Trial Cocaine-Induced Behavioral Sensitization And Conditioned Activity In Preweanling Rats, Anthony Michael Cortez
Persistence Of One-Trial Cocaine-Induced Behavioral Sensitization And Conditioned Activity In Preweanling Rats, Anthony Michael Cortez
Theses Digitization Project
The purpose of this thesis was to determine the persistence of one-shot context-specific and context-independent behavioral sensitization by administering a single pretreatment injection of cocaine or saline in either the home cage or a novel test chamber on PD 19 or PD 79. In order to examine the persistence of conditioned activity, adult rats were given an injection of saline after 1, 3, or 5 abstinence days. Preweanling rats were given an injection of saline after only 1 abstinence day.