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Full-Text Articles in Psychology
Role Of Dorsostriatal D1 And D2 Receptors In Modulating The Kappa Opioid-Mediated Locomotor Activity Of Preweanling Rats: Importance Of Synergistic Activation, Sergios Charntikov
Role Of Dorsostriatal D1 And D2 Receptors In Modulating The Kappa Opioid-Mediated Locomotor Activity Of Preweanling Rats: Importance Of Synergistic Activation, Sergios Charntikov
Theses Digitization Project
Infusions of the nonselective dopamine agonist R( - ) propylnorapomorphine (NPA) into the dorsal striatum of preweanling rats atteuates kappa opioid-mediated locomotor activity. The purpose of this thesis was to ascertain which dopamine receptor subtype (D1 or D2) is responsible for this effect. It was hypothsized that a) D1, but not D2, receptors in the dorsal striatum underlie NPA's ability to attenuate the kappa opioid-mediated locomotor activity of preweanling rats, and b) microinjectng SKF38393 (a D1 agonist), and not quinpirole (a D2 agonist), would attenuate kappa opioid-mediated locomotion.
Modulation Of Memory Formation Following Violations Of Conditioned Expectations, Dennis Antonio Amodeo
Modulation Of Memory Formation Following Violations Of Conditioned Expectations, Dennis Antonio Amodeo
Theses Digitization Project
Increment in attention to the conditioned stimulus (CS) leads to an increased rate of acquisition of new associations involving CS. While the neuroanatomical basis of the phenomenon is largely understood, little is known about the synaptic mechanisms underlying memory formation for prediction error. The current experiment tests the overall hypothesis that this specific form of memory depends on N-methyl-D-aspartate (NMDA) receptor activation.