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Rule-Based Categorization Deficits In Focal Basal Ganglia Lesion And Parkinson’S Disease Patients, Shawn W. Ell, Andrea Weinstein, Richard Ivry Jun 2010

Rule-Based Categorization Deficits In Focal Basal Ganglia Lesion And Parkinson’S Disease Patients, Shawn W. Ell, Andrea Weinstein, Richard Ivry

Psychology Faculty Scholarship

Patients with basal ganglia (BG) pathology are consistently found to be impaired on rule-based category learning tasks in which learning is thought to depend upon the use of an explicit, hypothesis-guided strategy. The factors that influence this impairment remain unclear. Moreover, it remains unknown if the impairments observed in patients with degenerative disorders such as Parkinson’s disease (PD) are also observed in those with focal BG lesions. In the present study, we tested patients with either focal BG lesions or PD on two categorization tasks that varied in terms of their demands on selective attention and working memory. Individuals with …


Cerebellar Pathology Does Not Impair Performance On Identification Or Categorization Tasks, Shawn Ell, Richard B. Ivry Sep 2008

Cerebellar Pathology Does Not Impair Performance On Identification Or Categorization Tasks, Shawn Ell, Richard B. Ivry

Psychology Faculty Scholarship

In comparison to the basal ganglia, prefrontal cortex, and medial temporal lobes, the cerebellum has been absent from recent research on the neural substrates of categorization and identification, two prominent tasks in the learning and memory literature. To investigate the contribution of the cerebellum to these tasks, we tested patients with cerebellar pathology (seven with bilateral degeneration, six with unilateral lesions, and two with midline damage) on rule-based and information-integration categorization tasks and an identification task. In rule-based tasks, it is assumed that participants learn the categories through an explicit reasoning process. In information-integration tasks, optimal performance requires the integration …