Psychology Commons^™

Examining Sucrose Subjective Response Among Individuals With Opioid Use Disorder, Taylor Anne Ochalek

Graduate College Dissertations and Theses

Aims: Opioid use disorder (OUD) is associated with significant morbidity and mortality, and opioid agonist treatment (OAT) with methadone or buprenorphine represents the most efficacious treatment. However, data suggest that chronic administration of opioids may be associated with significant weight gain, possibly by altering an organism’s perception of and preference for sweet foods. The primary aim of this laboratory study was to rigorously examine sucrose subjective response among adults receiving OAT and a comparison sample without OUD. As secondary outcomes, we also sought to compare the groups on additional baseline characteristics that may influence subjective sucrose response and weight gain …

Cost-Effectiveness Analysis Of Two Contraceptive Services Interventions For Women Receiving Medication For Opioid Use Disorder And At Risk Of Unintended Pregnancy, Heidi S. Melbostad

Graduate College Dissertations and Theses

Background: In the BCII randomized clinical trial, women receiving medication for opioid use disorder (OUD) and at risk of unintended pregnancy who received contraceptive services interventions co-located with an OUD treatment facility had significantly higher rates of prescription contraceptive use than those who received usual care. To support informed decision-making about using these interventions in community-based settings, I conducted a cost-effectiveness analysis to determine the costs and health benefits associated with these interventions.

Methods: I used the standard practice of calculating incremental cost effectiveness ratios (ICERs) between the trial conditions (i.e., usual care, contraceptive services, and contraceptive services + incentives) …