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Full-Text Articles in Psychology
Early Negative Affect In Males And Females With Fragile X Syndrome: Implications For Anxiety And Autism, Carla A. Will, Abigail L. Hogan, Elizabeth A. Will, Samuel Mcquillin, Bridgette L. Kelleher, Jane E. Roberts
Early Negative Affect In Males And Females With Fragile X Syndrome: Implications For Anxiety And Autism, Carla A. Will, Abigail L. Hogan, Elizabeth A. Will, Samuel Mcquillin, Bridgette L. Kelleher, Jane E. Roberts
Faculty Publications
Background Fragile X syndrome (FXS) is a genetic disorder that is highly comorbid with anxiety and autism spectrum disorder (ASD). Elevated negative affect in young children has been associated with increased risk for both anxiety and ASD; however, these relations remain poorly understood in FXS.
Methods The present prospective longitudinal study examined the trajectory of negative affect from infancy through preschool in males and females with FXS and typical development and its relation to anxiety and ASD.
Results Results indicate a complex association reflecting group, developmental, and sex effects. Specifically, the group with FXS displayed a trajectory of increasing negative …