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Neuroimaging Depression Risk In A Sample Of Never-Depressed Children, Matthew R. J. Vandermeer
Neuroimaging Depression Risk In A Sample Of Never-Depressed Children, Matthew R. J. Vandermeer
Electronic Thesis and Dissertation Repository
Children of mothers with a history of depression are at significantly higher risk for developing depression themselves. Although numerous mechanisms explaining this relationship have been proposed (Goodman & Gotlib, 1999), relatively little is known about the neural substrates of never-depressed children’s depression risk. Of the few studies that have used neuroimaging techniques to characterize risk-based differences in children’s neural structure, function, and functional connectivity, most have used samples that include participants with a personal history of depression or older samples (i.e., past the typical age of onset for depressive disorders). These approaches limit what can be determined regarding whether findings …