Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Psychology
The Impact Of Cannabis Use On Neuropsychological And Neural Biomarkers Of Treatment Response In Schizophrenia Spectrum Disorders, Melanie B. Thies
The Impact Of Cannabis Use On Neuropsychological And Neural Biomarkers Of Treatment Response In Schizophrenia Spectrum Disorders, Melanie B. Thies
Dissertations, Theses, and Capstone Projects
Cannabis use among patients with schizophrenia-spectrum disorders (SSD) is at significantly greater levels than in healthy populations but the impact of cannabis on neural mechanisms of clinical improvement is poorly understood. Cognitive functioning and neural connectivity are disrupted as a result of both SSD and cannabis use, and research indicates that neuropsychological capacity and connectivity of the striatum, a region involved in salience and reward processing, may be integral to effective antipsychotic drug (AP) treatment response. Despite this overlap, no previous research has investigated the effect of cannabis on the brain functions implicated in AP treatment response. The present study …
Serial Position Effect Profiles And Their Neuroanatomical Correlates: Predictors Of Conversion To Alzheimer's Disease, Isabelle K. Avildsen
Serial Position Effect Profiles And Their Neuroanatomical Correlates: Predictors Of Conversion To Alzheimer's Disease, Isabelle K. Avildsen
Dissertations, Theses, and Capstone Projects
The current study was designed to determine whether targeted, premorbid, neuropsychological measures of the serial position effect (SPE) can detect and explain risk for later development of Alzheimer’s disease (AD). The study tested the utility of SPE measures in healthy controls (HC) and individuals already diagnosed with mild cognitive impairment (MCI) or AD. Aim 1 was to determine whether these sensitive, valid neuropsychological measures can explain disease risk. SPE of list-learning are highly sensitive cognitive markers that capture important elements of both linguistic and amnestic mechanisms of encoding, learning, and retrieval. Using the Rey Auditory Verbal Learning Test (RAVLT), we …