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Dissertations

University of Missouri, St. Louis

Cortisol

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Full-Text Articles in Psychology

Cortisol Administration Normalizes Aberrant Functional Connectivity In Women With Depression, Adam C. Runyan Jul 2022

Cortisol Administration Normalizes Aberrant Functional Connectivity In Women With Depression, Adam C. Runyan

Dissertations

Previous resting-state functional connectivity (rsFC) research has identified aberrant connectivity in several large brain networks in depression, including the default mode (DMN), frontoparietal (FPN), and salience networks (SN). Connectivity of these networks is also related to depressive symptom severity and is affected by cortisol levels. To our knowledge, this is the first study to investigate the effects of acute cortisol administration on rsFC of DMN, FPN, and SN in individuals varying in depression history and severity. We collected resting-state fMRI scans for 74 women with and without a history of depressive disorder after administration of cortisol and placebo using a …


More Than Just Words On A Screen: A Biopsychosocial Approach To Understanding Effects Of Race-Related Media, Melinda Kittleman Mar 2020

More Than Just Words On A Screen: A Biopsychosocial Approach To Understanding Effects Of Race-Related Media, Melinda Kittleman

Dissertations

Racial disparities in physical and mental health are ongoing and well-documented problems in the United States. Black Americans, compared to White Americans, have higher risk of obesity, heart disease, cancer, depression, and substance abuse. Research suggests prejudice and discrimination play a role in racial health disparities. Everyday discrimination is considered a chronic, psychosocial stressor that impacts the health of Black Americans. A biopsychosocial approach states there are various factors that contribute to the pathway from discrimination to disease and proposes complex relationships that explain effects of racial discrimination on health. The current study examined social factors (race-related media), biological factors …