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Full-Text Articles in Psychology
Genomic Contributors To Individual Differences In Reward-Related Neural Activity, Lindsay Jane Michalski
Genomic Contributors To Individual Differences In Reward-Related Neural Activity, Lindsay Jane Michalski
Arts & Sciences Electronic Theses and Dissertations
Aberrant reward-related behavior, including impulsive and risk-taking behaviors, is a common feature of externalizing psychopathology (e.g., attention deficit hyperactivity disorder, antisocial personality disorder, and substance-use disorders). Through imaging studies, these behaviors have been linked to dysregulated reactivity within a diffuse reward-related corticostriatal neural network, including the striatum, frontal regions (namely orbital, ventromedial, and dorsolateral cortices), the insula, and the hippocampus. Because variability in risk-taking behavior and related psychopathology is moderately-to-largely heritable (i.e., with estimates ranging from 40 – 80%), a genetically-informed approach is well-positioned to provide valuable insight into the etiology of reward-related neural and behavioral phenotypes that characterize externalizing …
Effort, Avolition And Motivational Experience In Schizophrenia: Analysis Of Behavioral And Neuroimaging Data With Relationships To Daily Motivational Experience, Adam Culbreth
Arts & Sciences Electronic Theses and Dissertations
Recent research has suggested an association between motivational impairment in those with schizophrenia and reduced willingness to expend effort on experimental tasks. However, few studies have examined the neural correlates of effort-based decision-making in those with schizophrenia. In the current study, we aimed to examine willingness to expend effort, the associated neural circuitry of effort-based decision-making, and the impact of experimentally-defined effort-based decision-making on daily motivational experience in schizophrenia. We recruited 28 individuals with schizophrenia and 30 healthy controls to perform an effort-based decision-making task while undergoing fMRI scanning. In order to assess whether willingness to expend effort was associated …
Effort, Avolition And Motivational Experience In Schizophrenia: Analysis Of Behavioral And Neuroimaging Data With Relationships To Daily Motivational Experience, Adam Culbreth
Arts & Sciences Electronic Theses and Dissertations
Recent research has suggested an association between motivational impairment in those with schizophrenia and reduced willingness to expend effort on experimental tasks. However, few studies have examined the neural correlates of effort-based decision-making in those with schizophrenia. In the current study, we aimed to examine willingness to expend effort, the associated neural circuitry of effort-based decision-making, and the impact of experimentally-defined effort-based decision-making on daily motivational experience in schizophrenia. We recruited 28 individuals with schizophrenia and 30 healthy controls to perform an effort-based decision-making task while undergoing fMRI scanning. In order to assess whether willingness to expend effort was associated …