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Arts & Sciences Electronic Theses and Dissertations

2017

Dorsolateral prefrontal cortex

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Emotion Dysregulation And Functional Connectivity In Children With And Without A History Of Major Depressive Disorder, Katherine Lopez Aug 2017

Emotion Dysregulation And Functional Connectivity In Children With And Without A History Of Major Depressive Disorder, Katherine Lopez

Arts & Sciences Electronic Theses and Dissertations

Recent interest has emerged in understanding the neural mechanisms by which deficits in emotion regulation (ER) may relate to the development of depression. Cortico-limbic alterations reported in emotion dysregulation and depression may be one possible link. We examined the relationships between emotion dysregulation in school age, corticolimbic resting state functional connectivity (rs-FC) in preadolescence, and depressive symptoms in adolescence. Participants were 143 children from a longitudinal preschool onset depression study who completed the Children Sadness Management Scale (CSMS), Child Depression Inventory (CDI), and two resting state MRI scans. We examined rs-FC between four primary regions of interest (ROIs; bilateral dorsolateral …