Psychology Commons^™

Stability And Change: Stress Responses And The Shaping Of Behavioral Phenotypes Over The Life Span, Michael B. Hennessy, Sylvia Kaiser, Tobias Tiedtke, Norbert Sachser

Psychology Faculty Publications

In mammals, maternal signals conveyed via influences on hypothalamic-pituitary-adrenal (HPA) activity may shape behavior of the young to be better adapted for prevailing environmental conditions. However, the mother's influence extends beyond classic stress response systems. In guinea pigs, several hours (h) of separation from the mother activates not only the HPA axis, but also the innate immune system, which effects immediate behavioral change, as well as modifies behavioral responsiveness in the future. Moreover, the presence of the mother potently suppresses the behavioral consequences of this innate immune activation. These findings raise the possibility that long-term adaptive behavioral change can be …