Psychology Commons^™

Prediction-Based Learning And Processing Of Event Knowledge., Ken Mcrae, Kevin S Brown, Jeffrey L Elman

Psychology Publications

Knowledge of common events is central to many aspects of cognition. Intuitively, it seems as though events are linear chains of the activities of which they are comprised. In line with this intuition, a number of theories of the temporal structure of event knowledge have posited mental representations (data structures) consisting of linear chains of activities. Competing theories focus on the hierarchical nature of event knowledge, with representations comprising ordered scenes, and chains of activities within those scenes. We present evidence that the temporal structure of events typically is not well-defined, but it is much richer and more variable both …

Exploring Cognitive Maps Through Sketching, Melissa M. Nantais

Electronic Thesis and Dissertation Repository

Abstract

Periodic testing has been found to improve the accuracy of participants’ cognitive maps when an onscreen map is provided, however, it is unclear whether the same results would occur without the onscreen map. The current study investigated whether drawing a map periodically while exploring the virtual environment Silcton would improve cognitive map accuracy. Participants explored Silcton and were stopped every 4 minutes to either sketch a map of Silcton, identify items seen in Silcton, or colour an unrelated picture, and a baseline group was not stopped. All groups drew a final sketch map and completed a direction estimation task. …

Examining The Self-Schema Within A Cognitive Vulnerability-Stress Framework Of Mania, Nadia Maiolino

Electronic Thesis and Dissertation Repository

This dissertation aimed to inform a cognitive vulnerability-stress theory of mania, which addresses both the content and structure of the self-schema, along with the conditions under which these self-relevant cognitions are activated. Extant research on mania has primarily considered self-schema content, or an individual’s actual beliefs (e.g., “I am incompetent”). Although these investigations have successfully identified maladaptive self-beliefs associated with bipolar disorder, this research has been prone to inconsistencies and limited in distinguishing between mania and related forms of psychopathology (e.g., unipolar depression). Furthermore, very little research on mania has considered the organization of self-schema beliefs, referred to here as …

Child And Adolescent Sleep Disturbances And Psychopathology In A Mental Health Clinic Sample, Aviva Blacher

Electronic Thesis and Dissertation Repository

Sleep disturbances in children and adolescents (hereafter children) are associated with significant short-term and long-term impairments including more severe psychopathology, reduced cognitive functioning, and poorer general health. We know that children being treated in specialty mental health services are more likely to have sleep disturbances than community samples. We also know that relationships exist between sleep and psychopathology in children with specific disorders (e.g. ADHD, depression, etc.). However, few studies have investigated the relationship between sleep and psychopathology in a broad sample of children seen at mental health agencies. Both child factors and family factors may influence both sleep and …

A Macaque Connectome For Large-Scale Network Simulations In Thevirtualbrain, Kelly Shen, Gleb Bezgin, Michael Schirner, Petra Ritter, Stefan Everling, Anthony R. Mcintosh

Brain and Mind Institute Researchers' Publications

© 2019, The Author(s). Models of large-scale brain networks that are informed by the underlying anatomical connectivity contribute to our understanding of the mapping between the structure of the brain and its dynamical function. Connectome-based modelling is a promising approach to a more comprehensive understanding of brain function across spatial and temporal scales, but it must be constrained by multi-scale empirical data from animal models. Here we describe the construction of a macaque (Macaca mulatta and Macaca fascicularis) connectome for whole-cortex simulations in TheVirtualBrain, an open-source simulation platform. We take advantage of available axonal tract-tracing datasets and enhance the existing …

Predator-Induced Fear Causes Ptsd-Like Changes In The Brains And Behaviour Of Wild Animals, Liana Y. Zanette, Emma C. Hobbs, Lauren E. Witterick, Scott A. Macdougall-Shackleton, Michael Clinchy

Brain and Mind Institute Researchers' Publications

© 2019, The Author(s). Predator-induced fear is both, one of the most common stressors employed in animal model studies of post-traumatic stress disorder (PTSD), and a major focus of research in ecology. There has been a growing discourse between these disciplines but no direct empirical linkage. We endeavoured to provide this empirical linkage by conducting experiments drawing upon the strengths of both disciplines. Exposure to a natural cue of predator danger (predator vocalizations), had enduring effects of at least 7 days duration involving both, a heightened sensitivity to predator danger (indicative of an enduring memory of fear), and elevated neuronal …

Consciousness-Specific Dynamic Interactions Of Brain Integration And Functional Diversity, Andrea I. Luppi, Michael M. Craig, Ioannis Pappas, Paola Finoia, Guy B. Williams, Judith Allanson, John D. Pickard, Adrian M. Owen, Lorina Naci, David K. Menon, Emmanuel A. Stamatakis

Brain and Mind Institute Researchers' Publications

Prominent theories of consciousness emphasise different aspects of neurobiology, such as the integration and diversity of information processing within the brain. Here, we combine graph theory and dynamic functional connectivity to compare resting-state functional MRI data from awake volunteers, propofol-anaesthetised volunteers, and patients with disorders of consciousness, in order to identify consciousness-specific patterns of brain function. We demonstrate that cortical networks are especially affected by loss of consciousness during temporal states of high integration, exhibiting reduced functional diversity and compromised informational capacity, whereas thalamo-cortical functional disconnections emerge during states of higher segregation. Spatially, posterior regions of the brain’s default mode …

Altered Motor, Anxiety-Related And Attentional Task Performance At Baseline Associate With Multiple Gene Copies Of The Vesicular Acetylcholine Transporter And Related Protein Overexpression In Chat::Cre+ Rats, Craig P. Mantanona, Johan Alsiö, Joanna L. Elson, Beth M. Fisher, Jeffrey W. Dalley, Timothy Bussey, Ilse S. Pienaar

Brain and Mind Institute Researchers' Publications

© 2019, The Author(s). Transgenic rodents expressing Cre recombinase cell specifically are used for exploring mechanisms regulating behavior, including those mediated by cholinergic signaling. However, it was recently reported that transgenic mice overexpressing a bacterial artificial chromosome containing choline acetyltransferase (ChAT) gene, for synthesizing the neurotransmitter acetylcholine, present with multiple vesicular acetylcholine transporter (VAChT) gene copies, resulting in altered cholinergic tone and accompanying behavioral abnormalities. Since ChAT::Cre+ rats, used increasingly for understanding the biological basis of CNS disorders, utilize the mouse ChAT promotor to control Cre recombinase expression, we assessed for similar genotypical and phenotypical differences in such rats compared …

Are Specific Learning Disorders Truly Specific, And Are They Disorders?, Lien Peters, Daniel Ansari

Brain and Mind Institute Researchers' Publications

© 2019 The Authors Specific learning disorders, such as dyslexia and dyscalculia, are frequently studied to inform our understanding of cognitive development, genetic mechanisms and brain function. In this Opinion Paper, we discuss limitations of this research approach, including the use of arbitrary criteria to select groups of children, heterogeneity within groups and overlap between domains of learning. By drawing on evidence from cognitive science, neuroscience and genetics, we propose an alternative, dimensional framework. We argue that we need to overcome the problems associated with a categorical approach by taking into account interacting factors at multiple levels of analysis that …

Should It Stay Or Should It Go? Smartphone Dependency, Kira Foreman-Tran, Karina Schnurr, Ana C. Ruiz Pardo, John Paul Minda

Psychology Publications

As smartphones grow in use and popularity, it is important to understand the possible effects that varying levels of smartphone use may have on human cognition. Although smartphones provide many advantages for daily activities, one must also recognize the potential disadvantages. For example, smartphone use may lead to nomophobia, which is defined as the modern fear of not being able to access your smartphone or the internet (Yildirim & Correia, 2015). The present study used a pilot and main study to examine the effects smartphones have on human cognition. The pilot study was conducted to measure nomophobia, mobile phone involvement, …

Exploring The Links Between Social Anxiety And Depression In The Maintenance Of Romantic Relationships, Christian M. Hahn

Electronic Thesis and Dissertation Repository

Social anxiety is characterized by fear and avoidance of social encounters and has recently been associated with a variety of difficulties in romantic relationships. Complicating further investigation of these associations is the high degree of comorbidity between social anxiety and depressive symptomatology, which share several similarities in expression despite disparate underlying causes. The present thesis examines the unique influences of social anxiety and depression on a number of central aspects of relationship functioning and provide the first longitudinal investigation of the impacts of actor and partner social anxiety and depression on relationship quality and functioning. In Study 1, three independent …

Baseline And Stress-Induced Cognitive Control Deficits And Pro-Inflammatory Cytokines In Currently, Remitted, And Never Depressed Individuals, Katerina Rnic

Electronic Thesis and Dissertation Repository

Background: Cognitive theories posit that cognitive control deficits promote depression by reducing ability to self-regulate under stress. When activated by stress and accessible to working memory, negative cognitive content and structure (i.e., schemas), may interfere with cognitive control abilities, resulting in even greater declines in executive functioning. Moreover, burgeoning evidence indicates that social stress upregulates inflammation, resulting in a pro-inflammatory phenotype that drives depression pathogenesis. However, cognitive mechanisms underlying this process are not well understood. An objective of this study was to examine depression-related deficits in cognitive control and their association with poor self-regulation. Another purpose was to evaluate the …

A Developmental And Symptom-Level Approach To Comorbid Mental Health Disorders In Children, Elizabeth Thornley

Electronic Thesis and Dissertation Repository

This dissertation addresses current issues in the conceptualization and classification of childhood mental health issues (e.g., impact of sex/age on symptoms, comorbidity, limits of traditional models). In contrast to traditional models, the importance and value of utilizing individual symptoms as primary variables of interest is presented. This first study consisted of 9565 participants (M = 12.06, SD = 3.57, 58% males). Results for youth with no history of trauma indicated sex differences in symptom expression consistent with what has been previously shown in the literature; however, a complex presentation of attention-related symptoms was identified for females. Similar sex differences …

The Role Of Social Disconnection In The Relationship Between Perfectionism And Psychological Distress, Samantha Chen

Electronic Thesis and Dissertation Repository

This dissertation investigated the interpersonal mechanisms through which various aspects of perfectionism confer risk for psychological outcomes. Three studies were conducted based on the Perfectionism Social Disconnection Model (Hewitt, Flett, & Mikail, 2017), which proposes that individuals with higher levels of perfectionism may experience significant social disconnection, which then lead to a variety of maladaptive outcomes. Study 1 examined the longitudinal impacts of trait perfectionism and sense of relatedness on the variance in change in psychological outcomes. Findings showed that negative perceptions of relatedness partially mediated the link between socially prescribed perfectionism and psychological distress three months later; however, this …

Functional Localization Of The Frontal Eye Fields In The Common Marmoset Using Microstimulation, Janahan Selvanayagam, Kevin D. Johnston, David J. Schaeffer, Lauren K. Hayrynen, Stefan Everling

Brain and Mind Institute Researchers' Publications

Copyright © 2019 the authors. The frontal eye field (FEF) is a critical region for the deployment of overt and covert spatial attention. Although investigations in the macaque continue to provide insight into the neural underpinnings of the FEF, due to its location within a sulcus, the macaque FEF is virtually inaccessible to electrophysiological techniques such as high-density and laminar recordings. With a largely lissencephalic cortex, the common marmoset (Callithrix jacchus) is a promising alternative primate model for studying FEF microcircuitry. Putative homologies have been established with the macaque FEF on the basis of cytoarchitecture and connectivity; however, physiological investigation …

Sign And Speech Share Partially Overlapping Conceptual Representations, Samuel Evans, Cathy J. Price, Jörn Diedrichsen, Eva Gutierrez-Sigut, Mairéad Macsweeney

Brain and Mind Institute Researchers' Publications

© 2019 The Author(s) Conceptual knowledge is fundamental to human cognition. Yet, the extent to which it is influenced by language is unclear. Studies of semantic processing show that similar neural patterns are evoked by the same concepts presented in different modalities (e.g., spoken words and pictures or text) [1–3]. This suggests that conceptual representations are “modality independent.” However, an alternative possibility is that the similarity reflects retrieval of common spoken language representations. Indeed, in hearing spoken language users, text and spoken language are co-dependent [4, 5], and pictures are encoded via visual and verbal routes [6]. A parallel approach …

Adaptation To Conflict Frequency: Non-Conflict Learning Is Not The Whole Story, Giacomo Spinelli

Electronic Thesis and Dissertation Repository

In the Stroop task, smaller congruency effects (i.e., the color-naming difference between incongruent items, e.g., the word RED in the color blue, and congruent items, e.g., RED in red) are found in conditions in which incongruent items are frequent vs. infrequent. Although the traditional explanation for these “Proportion-Congruent effects” is that attention to task-relevant information is more focused in frequently-conflicting conditions (a process involving adaptation to conflict frequency), Proportion-Congruent paradigms typically have not controlled for the impact of more general learning processes, particularly 1) learning of word-response contingencies (contingency learning), 2) learning about the predictive nature of the stimuli (stimulus …

Variational Representational Similarity Analysis, Karl J. Friston, Jörn Diedrichsen, Emma Holmes, Peter Zeidman

Brain and Mind Institute Researchers' Publications

© 2019 The Authors This technical note describes a variational or Bayesian implementation of representational similarity analysis (RSA) and pattern component modelling (PCM). It considers RSA and PCM as Bayesian model comparison procedures that assess the evidence for stimulus or condition-specific patterns of responses distributed over voxels or channels. On this view, one can use standard variational inference procedures to quantify the contributions of particular patterns to the data, by evaluating second-order parameters or hyperparameters. Crucially, this allows one to use parametric empirical Bayes (PEB) to infer which patterns are consistent among subjects. At the between-subject level, one can then …

Cognitive Change In Cognitive-Behavioural Therapy, Leanne Quigley, David J A Dozois, R Michael Bagby, Daniela S S Lobo, Lakshmi Ravindran, Lena C Quilty

Psychology Publications

BACKGROUND: Although cognitive-behavioural therapy (CBT) is a well-established treatment for adult depression, its efficacy and efficiency may be enhanced by better understanding its mechanism(s) of action. According to the theoretical model of CBT, symptom improvement occurs via reductions in maladaptive cognition. However, previous research has not established clear evidence for this cognitive mediation model.

METHODS: The present study investigated the cognitive mediation model of CBT in the context of a randomized controlled trial of CBT v. antidepressant medication (ADM) for adult depression. Participants with major depressive disorder were randomized to receive 16 weeks of CBT (n = 54) or ADM …

A Sound-Sensitive Source Of Alpha Oscillations In Human Non-Primary Auditory Cortex, Alexander J. Billig, Björn Herrmann, Ariane E. Rhone, Phillip E. Gander, Kirill V. Nourski, Beau F. Snoad, Christopher K. Kovach, Hiroto Kawasaki, Matthew A. Howard, Ingrid S. Johnsrude

Brain and Mind Institute Researchers' Publications

Copyright © 2019 Billig, Herrmann et al. The functional organization of human auditory cortex can be probed by characterizing responses to various classes of sound at different anatomical locations. Along with histological studies this approach has revealed a primary field in posteromedial Heschl's gyrus (HG) with pronounced induced high-frequency (70-150 Hz) activity and short-latency responses that phase-lock to rapid transient sounds. Low-frequency neural oscillations are also relevant to stimulus processing and information flow, however, their distribution within auditory cortex has not been established. Alpha activity (7-14 Hz) in particular has been associated with processes that may differentially engage earlier versus …

Death Of The Clinic: Trans-Informing The Clinical Gaze To Counter Epistemic Violence, Diana E. Kuhl

Electronic Thesis and Dissertation Repository

This case study research (Patton, 2002, 2014; Flyvberg, 2006) has grown out of an awareness of deep resistance from the psy disciplines to trans-informed epistemologies as a source of legitimate knowledge (Tosh, 2015, 2016; Winters, 2008). It focuses on examining how the closure of The Gender Identity Clinic (GIC) for Children and Youth at the Centre for Addiction and Mental Health (CAMH) in Toronto, Ontario, Canada, signaled a paradigm shift from the ‘treatment model’ to the ‘affirmative model’ with respect to clinical approaches for supporting trans and gender diverse children and youth. As such the case study involved tracing the …

An Accurate Registration Of The Bigbrain Dataset With The Mni Pd25 And Icbm152 Atlases., Yiming Xiao, Jonathan C Lau, Taylor Anderson, Jordan Dekraker, D Louis Collins, Terry Peters, Ali R Khan

Brain and Mind Institute Researchers' Publications

Brain atlases that encompass detailed anatomical or physiological features are instrumental in the research and surgical planning of various neurological conditions. Magnetic resonance imaging (MRI) has played important roles in neuro-image analysis while histological data remain crucial as a gold standard to guide and validate such analyses. With cellular-scale resolution, the BigBrain atlas offers 3D histology of a complete human brain, and is highly valuable to the research and clinical community. To bridge the insights at macro- and micro-levels, accurate mapping of BigBrain and established MRI brain atlases is necessary, but the existing registration is unsatisfactory. The described dataset includes …

In Search Of Psychiatric Kinds: Natural Kinds And Natural Classification In Psychiatry, Nicholas Slothouber

Electronic Thesis and Dissertation Repository

In recent years both philosophers and scientists have asked whether or not our current kinds of mental disorder—e.g., schizophrenia, depression, bipolar disorder—are natural kinds; and, moreover, whether or not the search for natural kinds of mental disorder is a realistic desideratum for psychiatry. In this dissertation I clarify the sense in which a kind can be said to be “natural” or “real” and argue that, despite a few notable exceptions, kinds of mental disorder cannot be considered natural kinds. Furthermore, I contend that psychopathological phenomena do not cluster together into kinds in the way that paradigmatic natural kinds (e.g., chemical …

Promoting Mentally Healthy Classrooms: Evaluation Of Online Mental Health Literacy Instruction In Pre-Service Teacher Education, E. Robyn Masters

Electronic Thesis and Dissertation Repository

To better understand how to prepare large numbers of pre-service teachers for their role in creating and leading mentally healthy classrooms, this program evaluation explores outcomes related to an online mental health literacy course at a large central Canadian university. The course was delivered to 275 teacher education students simultaneously over 10-weeks and 20-hours of online instruction and professional reflection. Results indicated significant improvement in self-reported levels of mental health literacy, stigma toward mental illness, and self-efficacy for teaching students with diverse challenges. Qualitative reviews of participant feedback identified the most valuable aspects of the course and the ways in …

How Do Humans Process Magnitudes? An Examination Of The Neural And Cognitive Underpinnings Of Symbols, Quantities, And Size In Adults And Children, Helen Moriah Sokolowski

Electronic Thesis and Dissertation Repository

A striking way that humans differ from other species is our unique ability to represent and manipulate symbols. This ability to process numerical magnitudes symbolically (e.g., ‘three’, ‘3’) is widely thought to be supported by an ancient system that evolved to process nonsymbolic numerical magnitudes (i.e., quantities). In this thesis, I present four empirical studies to uncover whether symbolic representations are indeed supported by the system that evolved to process quantities, or if symbolic representations are sub-served by a similar but ultimately distinct system.

In experiments 1 and 2, I investigate how the adult brain processes symbols and quantities using …

How Does The Brain Represent Digits? Investigating The Neural Correlates Of Symbolic Number Representation Using Fmri-Adaptation, Celia Goffin

Electronic Thesis and Dissertation Repository

How does the brain represent numerical symbols (e.g., Arabic digits)? Activity in left parietal regions correlates with symbolic number processing. Research with functional resonance imaging adaptation (fMRI-A) indicates that the intraparietal sulcus (IPS) exhibits a rebound (increase in activation) effect when a repeatedly presented number is followed by a new number. Importantly, this rebound effect is modulated by numerical ratio as well as the difference between presented numbers (distance). This ratio-dependent rebound effect could reflect a link between symbolic numerical representation and an approximate number system (ANS). In this doctoral dissertation, fMRI-A is used to investigate mechanisms underlying symbolic number …

Adolescents’ Perceptions And Responses To Peer Mental Health Challenges And Problematic Behaviours Following A Social-Emotional Learning Program, Jessica Sommers

Electronic Thesis and Dissertation Repository

Vulnerable youth may be more susceptible to developing problematic behaviours and mental health challenges, including anxious and depressive symptoms, suicidal ideation, substance misuse, and unhealthy relationships. Social-emotional learning programs like The Healthy Relationships Plus Program (HRPP) can foster positive youth development by including training on mental health literacy, developing skills in help-seeking, and providing opportunities to practice difficult conversations. This study explored youth’s responses to hypothetical challenges faced by peers with a group of sixty-three adolescents who had participated in the HRPP. Responses to four distinct scenarios were collected to examine youths’ perceptions of various challenges and problematic behaviours, including …

A Framework For Evaluating Correspondence Between Brain Images Using Anatomical Fiducials., Jonathan C Lau, Andrew G Parrent, John Demarco, Geetika Gupta, Jason Kai, Olivia W Stanley, Tristan Kuehn, Patrick J Park, Kayla Ferko, Ali R Khan, Terry M Peters

Brain and Mind Institute Researchers' Publications

Accurate spatial correspondence between template and subject images is a crucial step in neuroimaging studies and clinical applications like stereotactic neurosurgery. In the absence of a robust quantitative approach, we sought to propose and validate a set of point landmarks, anatomical fiducials (AFIDs), that could be quickly, accurately, and reliably placed on magnetic resonance images of the human brain. Using several publicly available brain templates and individual participant datasets, novice users could be trained to place a set of 32 AFIDs with millimetric accuracy. Furthermore, the utility of the AFIDs protocol is demonstrated for evaluating subject-to-template and template-to-template registration. Specifically, …

The Impact Of Statistical Learning On Language And Social Competency In Asd And Adhd: Divergent Findings, Kaitlyn M.A Parks

Electronic Thesis and Dissertation Repository

Statistical learning is a process that allows individuals to extract regularities from the environment and plays an important role in language acquisition, speech segmentation, and aspects of social behaviour. Little is known about the contribution of statistical learning impairments on Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) related traits. The current study examined whether impairments in auditory and visual statistical learning are related to ASD and ADHD traits, language, and social competency. Decreased auditory, but not visual statistical learning abilities was related to increased autism traits and visual statistical learning and social competency abilities were mediated by language comprehension. …

Ceos Don't Wear Afros: Exploring The Justification-Suppression Of Prejudice Against Black Women In The Workplace, Bukun F. Adegbembo

Electronic Thesis and Dissertation Repository

There have been numerous cases where Black women have been disparaged for wearing their natural hair or Afrocentric hairstyles in the workplace. While some have argued that such mistreatment was due to racism, others have stated that it was a case of not adhering to a professional dress code. In line with the justification-suppression model of prejudice, this research investigated whether prejudice against Black women in the workplace is expressed when they wear Afrocentric hairstyles as this allows the bias to be justified under the guise of normative standards of professionalism. Our pilot and main study showed that the Black …