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Full-Text Articles in Psychology
Zonulin As A Mediator Of Psychological Stress And Periodontal Disease, Casey D. Wright
Zonulin As A Mediator Of Psychological Stress And Periodontal Disease, Casey D. Wright
Graduate Theses, Dissertations, and Problem Reports
The prevalence of chronic inflammatory diseases is on the rise. Some have posited the permeability of tight junctions in gastrointestinal epithelium tissues as a potential mechanism for precipitating inflammatory processes throughout the body. Zonulin is the only known modulator of tight junction permeability and has been implicated in numerous chronic inflammatory processes (e.g., proinflammatory cytokine production) and diseases, more generally. The role of zonulin in oral inflammation, however, has yet to be explored. Periodontal disease is the most common oral inflammatory condition and primary perpetrator of tooth loss. Periodontal disease also is associated with a number of other health problems …
The Role Of High-Fat Diets In Exacerbating Cognitive Deficits After Traumatic Brain Injury, Michelle A. Frankot
The Role Of High-Fat Diets In Exacerbating Cognitive Deficits After Traumatic Brain Injury, Michelle A. Frankot
Graduate Theses, Dissertations, and Problem Reports
Traumatic brain injury (TBI) can cause chronic psychiatric-like impairments that may be driven by inflammation in the brain. In the current study, inflammation was upregulated using a high-fat diet (HFD) to assess the role of inflammation in TBI-induced deficits. Rats were randomly assigned to receive an HFD or calorie-matched low-fat diet (LFD) for the duration of the experiment. After two weeks of free access to their respective diets, rats began behavioral training on the Rodent Gambling Task (RGT), during which they were allowed to freely choose to nosepoke in one of four holes in a standard operant chamber. Responses in …