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Full-Text Articles in Psychology
Análisis Molecular Del Gen Gabrb3 En Pacientes Con Autismo: Estudio Exploratorio [Molecular Analysis Of The Gabrb3 Gene In Autistic Patients: An Exploratory Study], Ernesto Solís-Añez, Wilmer Delgado-Luengo, Lisbeth Borjas-Fuentes, William Zabala, Nailet Arráiz, Lennie Pineda, María Gabriela Portillo, Sandra González-Ferrer, José Antonio Chacín, Joaquín A. Peña, Cecilia Montiel-Nava
Análisis Molecular Del Gen Gabrb3 En Pacientes Con Autismo: Estudio Exploratorio [Molecular Analysis Of The Gabrb3 Gene In Autistic Patients: An Exploratory Study], Ernesto Solís-Añez, Wilmer Delgado-Luengo, Lisbeth Borjas-Fuentes, William Zabala, Nailet Arráiz, Lennie Pineda, María Gabriela Portillo, Sandra González-Ferrer, José Antonio Chacín, Joaquín A. Peña, Cecilia Montiel-Nava
Psychological Science Faculty Publications and Presentations
Autism is a complex neurodevelopmental disorder characterized by impairment of social interaction, language, communication, and stereotyped, repetitive behavior. Genetic predisposition to Autism has been demonstrated in families and twin studies. There is evidence (linkage and genetic association, biochemical, neuropathological, functional and cytogenetic) that the gamma-amino-butyric acid receptor beta 3 subunit gene (GABRB3) at 15q11-q13 is a susceptibility candidate gene for Autism. The aim of this exploratory study was to identify new variants of this gene. We performed the molecular analysis (SSCP/Sequencing) of 10 exons and its intronic flanking regions of GABRB3, using a candidate gene screening approach in 18 idiopathic …