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Non-24-Hour Sleep-Wake Syndrome Following A Car Accident, D. B. Boivin, F. O. James, Jonathan Bruce Santo, O. Caliyurt, C. Chalk
Non-24-Hour Sleep-Wake Syndrome Following A Car Accident, D. B. Boivin, F. O. James, Jonathan Bruce Santo, O. Caliyurt, C. Chalk
Psychology Faculty Publications
The authors report the case of a 39-year-old sighted woman who displayed non-24-hour sleep–wake cycles following a car accident. The phase relationship between endogenous circadian markers such as plasma melatonin and 6-sulfatoxymelatonin rhythms and self-selected sleep times was abnormal. A laboratory investigation indicated that she was sensitive to bright light as a circadian synchronizer. MRI and brain CT scans were normal, but microscopic brain damage in the vicinity of the suprachiasmatic nucleus or its output pathways is plausible.