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Serotonin Transporter (5-Httlpr) Genotype And Childhood Trauma Are Associated With Individual Differences In Decision Making, Scott Stoltenberg
Serotonin Transporter (5-Httlpr) Genotype And Childhood Trauma Are Associated With Individual Differences In Decision Making, Scott Stoltenberg
Scott F. Stoltenberg
The factors that influence individual differences in decision making are not yet fully characterized, but convergent evidence is accumulating that implicates serotonin (5-HT) system function. Therefore, both genes and environments that influence serotonin function are good candidates for association with risky decision making. In the present study we examined associations between common polymorphisms in the serotonin transporter gene (SLC6A4; 5-HTTLPR and rs25531), the experience of childhood trauma and decision making on the Iowa gambling task (IGT) in 391 (64.5% female) healthy Caucasian adults. Homozygosity for the 5-HTTLPR L allele was associated with riskier decision making in the first block of …