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Full-Text Articles in Psychology
Patient Perspectives On Chronic Rhinosinusitis In Cystic Fibrosis: Symptom Prioritization In The Era Of Highly Effective Modulator Therapy, Christine Liu, Ethan J. Han, Jakob L. Fischer, Jess C. Mace, Jose L. Mattos, Karolin Markarian, Jeremiah Alt, Todd Bodner, Naweed I. Chowdhury, Multiple Additional Authors
Patient Perspectives On Chronic Rhinosinusitis In Cystic Fibrosis: Symptom Prioritization In The Era Of Highly Effective Modulator Therapy, Christine Liu, Ethan J. Han, Jakob L. Fischer, Jess C. Mace, Jose L. Mattos, Karolin Markarian, Jeremiah Alt, Todd Bodner, Naweed I. Chowdhury, Multiple Additional Authors
Psychology Faculty Publications and Presentations
Background
Chronic rhinosinusitis (CRS) is common in people with cystic fibrosis (PwCF). Rhinologic symptom prioritization and areas that influence CRS treatment choices, including pursuing endoscopic sinus surgery (ESS), remain understudied.
Methods
Adult PwCF + CRS were enrolled at eight centers into a prospective, observational study (2019–2023). Participants were administered the 22-SinoNasal Outcome Test (SNOT-22) survey and a modified SNOT-22 instrument examining symptom importance. We determined importance rankings for individual symptoms and SNOT-22 symptom importance subdomains in two sets of subgroups—those pursuing ESS versus continuing medical management (CMT), and those on elexacaftor/tezacaftor/ivacaftor (ETI) versus not on ETI.
Results
Among 69 participants, …