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Full-Text Articles in Psychology
Semantic Memory Functional Mri And Cognitive Function After Exercise Intervention In Mild Cognitive Impairment, J Carson Smith, Kristy A. Nielson, Piero Antuono, Jeri-Annette Lyons, Ryan J. Hanson, Alissa Butts, Nathan Hantke, Matthew D. Verber
Semantic Memory Functional Mri And Cognitive Function After Exercise Intervention In Mild Cognitive Impairment, J Carson Smith, Kristy A. Nielson, Piero Antuono, Jeri-Annette Lyons, Ryan J. Hanson, Alissa Butts, Nathan Hantke, Matthew D. Verber
Psychology Faculty Research and Publications
Mild cognitive impairment (MCI) is associated with early memory loss, Alzheimer's disease (AD) neuropathology, inefficient or ineffective neural processing, and increased risk for AD. Unfortunately, treatments aimed at improving clinical symptoms or markers of brain function generally have been of limited value. Physical exercise is often recommended for people diagnosed with MCI, primarily because of its widely reported cognitive benefits in healthy older adults. However, it is unknown if exercise actually benefits brain function during memory retrieval in MCI. Here, we examined the effects of exercise training on semantic memory activation during functional magnetic resonance imaging (fMRI). Seventeen MCI participants …
Comparison Of Semantic And Episodic Memory Bold Fmri Activation In Predicting Cognitive Decline In Older Adults, Nathan Hantke, Kristy A. Nielson, John L. Woodard, Leslie M. Guidotti Breting, Alissa Butts, Michael Seidenberg, J. Carson Smith, Sally Durgerian, Melissa A. Lancaster, Monica Matthews, Michael Sugarman, Stephen M. Rao
Comparison Of Semantic And Episodic Memory Bold Fmri Activation In Predicting Cognitive Decline In Older Adults, Nathan Hantke, Kristy A. Nielson, John L. Woodard, Leslie M. Guidotti Breting, Alissa Butts, Michael Seidenberg, J. Carson Smith, Sally Durgerian, Melissa A. Lancaster, Monica Matthews, Michael Sugarman, Stephen M. Rao
Psychology Faculty Research and Publications
Previous studies suggest that task-activated functional magnetic resonance imaging (fMRI) can predict future cognitive decline among healthy older adults. The present fMRI study examined the relative sensitivity of semantic memory (SM) versus episodic memory (EM) activation tasks for predicting cognitive decline. Seventy-eight cognitively intact elders underwent neuropsychological testing at entry and after an 18-month interval, with participants classified as cognitively “Stable” or “Declining” based on ≥1.0 SD decline in performance. Baseline fMRI scanning involved SM (famous name discrimination) and EM (name recognition) tasks. SM and EM fMRI activation, along with Apolipoprotein E (APOE) ε4 status, served as predictors of cognitive …