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The Synergistic Effects Of Methylphenidate On The Behavioral Effects Of Nicotine, Kristen K. Leedy
The Synergistic Effects Of Methylphenidate On The Behavioral Effects Of Nicotine, Kristen K. Leedy
Undergraduate Honors Theses
One of the most common childhood disorders, attention-deficit hyperactivity disorder (ADHD) places individuals at a higher risk for nicotine (NIC) dependence. Approximately 37.2% of individuals with ADHD currently smoke compared to the 18.3% of individuals with no record of mental illness. Methylphenidate (MPH; Trade name Ritalin) is the most commonly prescribed treatment for ADHD. Research regarding the synergistic effects of MPH and NIC, however, is divided. Some research indicates that MPH may enhance susceptibility to NIC effects, whereas other studies report that MPH may inhibit sensitization to NIC. The present study examines the effects of pre-exposure to MPH (1.0 mg/kg) …