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Full-Text Articles in Psychology
Activity In Both Hippocampus And Perirhinal Cortex Predicts The Memory Strength Of Subsequently Remembered Information, Y. Schrager, C. Brock Kirwan, L. R. Squire
Activity In Both Hippocampus And Perirhinal Cortex Predicts The Memory Strength Of Subsequently Remembered Information, Y. Schrager, C. Brock Kirwan, L. R. Squire
Faculty Publications
An influential idea about memory and medial temporal lobe function suggests that hippocampal activity predicts subsequent recognition success only when decisions are based on recollection, whereas perirhinal activity predicts subsequent recognition success when decisions are based on familiarity. An alternative idea is that hippocampal and perirhinal activity are both sensitive to the level of overall memory strength. Using functional magnetic resonance imaging, we have tested the relationship between brain activity during learning and subsequent memory strength. Activity in a number of cortical regions (including regions within what has been termed the default network) was negatively correlated with subsequent memory strength, …
Fmri Evidence Of Group Differences On The Word Memory Test In A Sample Of Traumatic Brain Injury Patients, James Douglas Larsen
Fmri Evidence Of Group Differences On The Word Memory Test In A Sample Of Traumatic Brain Injury Patients, James Douglas Larsen
Theses and Dissertations
The Word Memory Test (WMT) is a popular effort test that requires participants to memorize lists of paired words and repeat them back in a variety of different memory tasks. Four brain injured patients participated in two trials of the delayed recall (DR) portion of the WMT while undergoing fMRI scanning. In the first trial subjects put forth full effort, and during the second trial subjects were instructed to simulate increased memory impairment in order to represent poor effort. fMRI activation from both trials were compared in order to contrast full and simulated poor effort activation patterns during the WMT. …
Clinical Applications Of Fmri: An Adaptation Of A Standard Neuropsychological Battery, Alina K. F. Ichimura
Clinical Applications Of Fmri: An Adaptation Of A Standard Neuropsychological Battery, Alina K. F. Ichimura
Theses and Dissertations
The goal of this study is to advance the utility of functional brain imaging as a tool for the diagnosis and treatment of neurological disorders by creating a statistical database of functional MRI (fMRI) brain activation patterns collected from neurologically and psychiatrically unimpaired subjects. Continuous fMRI scans have been obtained from each subject while s/he performed a variety of cognitive tasks that are commonly found in standard neurological and cognitive assessment batteries. The collected fMRI data has been processed, analyzed, and converted into database which can be used as a reference of reliable indices of normal brain activity patterns for …
Clinical Application Of Standardized Cognitive Assessment Using Fmri. I. Matrix Reasoning, Mark D. Allen, Alina K. Fong
Clinical Application Of Standardized Cognitive Assessment Using Fmri. I. Matrix Reasoning, Mark D. Allen, Alina K. Fong
Faculty Publications
Functional MRI is increasingly recognized for its potential as a powerful new tool in clinical neuropsychology. This is likely due to the fact that, with some degree of innovation, it is possible to convert practically any familiar cognitive test into one that can be performed in the MRI scanning environment. However, like any assessment approach, meaningful interpretation of fMRI data for the purpose of patient evaluation crucially requires normative data derived from a sample of unimpaired persons, against which individual patients may be compared. Currently, no such normative data are available for any fMRI-based cognitive testing protocol. In this paper, …
Clinical Application Of Standardized Cognitive Assessment Using Fmri. Ii. Verbal Fluency, Mark D. Allen, Alina K. Fong
Clinical Application Of Standardized Cognitive Assessment Using Fmri. Ii. Verbal Fluency, Mark D. Allen, Alina K. Fong
Faculty Publications
In this study, we describe an fMRI version of the verbal fluency test. This is the second in a series of fMRI adaptations of classical neuropsychological tests, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that makes individual patient evaluation possible in terms of familiar z-score distributions. This fMRI protocol is shown to have strong convergent validity with the FAS phonemic fluency test and to elicit activation patterns highly consistent with a large body of previous neuroimaging studies of verbal fluency. We also present a case study, in which …